The efficacy and safety of a coumarin-/troxerutin-combination (SB-LOT) in patients with chronic venous insufficiency: A double blind placebo-controlled randomised study

Vasa - Journal of Vascular Diseases

Volumn 31, Issue 3, 2002, Pages 185-190

  Vanscheidt, Wolfgang ^a   Rabe, E ^a   Naser Hijazi, B ^a   Ramelet, A A ^a   Partsch, H ^a   Diehm, C ^a   Schultz Ehrenburg, U ^a   Spengel, F ^a   Wirsching, M ^a   Gotz V ^a   Schnitker, J ^a   Henneicke Von Zepelin, H H ^a  

^a Clinic for Wound Biology   (Germany)

Author keywords

Compression stockings; Coumarin; Oedema; Troxerutin; Venous insufficiency

Indexed keywords

COUMARIN; MELILOTUS EXTRACT; PLACEBO; TROXERUTIN; COUMARIN DERIVATIVE; DRUG DERIVATIVE; MONOXERUTIN;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CHRONIC VEIN INSUFFICIENCY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG MIXTURE; DRUG SAFETY; FEMALE; HUMAN; LEG COMPRESSION; MAJOR CLINICAL STUDY; MALE; NAUSEA; RANDOMIZED CONTROLLED TRIAL; STOMACH PAIN; TREATMENT OUTCOME; VOMITING; BANDAGE; DELAYED RELEASE FORMULATION; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; EDEMA; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; ORAL DRUG ADMINISTRATION; VEIN INSUFFICIENCY;

ADMINISTRATION, ORAL; ADULT; AGED; BANDAGES; COMBINED MODALITY THERAPY; COUMARINS; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; EDEMA; FEMALE; HUMANS; HYDROXYETHYLRUTOSIDE; MALE; MIDDLE AGED; TREATMENT OUTCOME; VENOUS INSUFFICIENCY;

EID: 77954818134     PISSN: 03011526     EISSN: None     Source Type: Journal    
DOI: 10.1024/0301-1526.31.3.185     Document Type: Article

References (25)

1. Development and validation of a disease specific questionnaire on the quality of life of patients with chronic venous insufficiency
2. Therapie des venösen ödems-effizienz einer medikamentösen therapie zusätzlich zur kompressionsbehandlung
3. Verstärkte wirksamkeit der intermittierenden druckbehandlung durch medikamentöse begleittherapie
4. Therapeutic effect of venotonics in chronic venous insufficiency
5. Management of venous edema: Insight from an international task force
6. The management of chronic venous disorders on the leg: An evidence-based report of an international task force
7. Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency
8. Prevalence of varicose veins and chronic venous insufficiency in men and woman in the general population: Edingburgh Vein Study
9. Leitlinien zur diagnostik und therapie der chronisch venösen insuffizienz (CVI)
10. Behandlung der chronischvenösen insuffizienz
11. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (Stages I-III)
12. Lebensqualität bei chronisch-venöser insuffizienz-ergebnisse einer untersuchung mit dem neu entwickelten tübinger fragebogen zur messung der lebensqualität von CVI-patienten (TLQ-CVI)
13. The behaviour of blood clotting under long term treatment with 5,6-benzo-a-pryon (coumarin). Double blind study
14. Procedures for two-sample comparisons with multiple endpoints controlling the Experimentwise error rate
15. Procedure for comparing samples with multiple endpoints
16. Mode of action of coumarin in the treatment of thermal injuries
17. Reporting standards in venous diseases: An update
18. Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency
19. The German version of the EUROQOL quality of life questionnaire
20. Behandlung des ulcus cruris mit einem benzopyron-präparat
21. Investigation of the efficacy of oxerutins compared to placebo in patients with chronic venous insufficiency treated with compression stockings
22. Socio-economic impact of chronic venous insufficiency
23. Guidelines for testing drugs for chronic venous insufficiency
24. Double-blind trial to the efficacy of troxerutin in chronic venous insufficiency