Dissolution improvement of electrospun nanofiber-based solid dispersions for acetaminophen

AAPS PharmSciTech

Volumn 11, Issue 2, 2010, Pages 809-817

  Yu, Deng Guang ^a   Branford White, Christopher ^b   White, Kenneth ^b   Li, Xue Lian ^a   Zhu, Li Min ^a  

^a DONGHUA UNIVERSITY   (China)

^b LONDON METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Drug loaded nanofiber; Electrospinning; Microstructural characteristics; Poorly water soluble drug; Solid dispersion

Indexed keywords

NANOFIBER; PARACETAMOL; POLYMER; POVIDONE; ANALGESIC AGENT; DELAYED RELEASE FORMULATION; EMULSION; NANOCAPSULE;

ARTICLE; ARTIFICIAL MEMBRANE; CONTROLLED STUDY; DISPERSION; DISSOLUTION; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPINNING; FREEZE DRYING; HEATING; HYDROPHILICITY; IN VITRO STUDY; PHARMACEUTICAL ENGINEERING; POROSITY; PRIORITY JOURNAL; SOLID DISPERSION; SURFACE PROPERTY; VACUUM DRYING; ADMINISTRATION AND DOSAGE; ADSORPTION; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG FORMULATION; ELECTROCHEMISTRY; EMULSION; PROCEDURES; ROTATION; SYNTHESIS; ULTRASTRUCTURE;

ACETAMINOPHEN; ADSORPTION; ANALGESICS, NON-NARCOTIC; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; ELECTROCHEMISTRY; EMULSIONS; NANOCAPSULES; ROTATION;

EID: 77954814859     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9438-4     Document Type: Article

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