The post-antifungal effect (PAFE) of amphotericin B, nystatin, ketoconazole and 5-fluorocytosine and its impact on the colonization traits of Candida glabrata

Medical Mycology

Volumn 48, Issue 5, 2010, Pages 725-734

  Samaranayake, Y H ^a   Yau, J Y Y ^a   Thein, Z M ^a   Jayatilake, J A M S ^b   Yeung, K W S ^a   Samaranayake, L P ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF PERADENIYA   (Sri Lanka)

Author keywords

Antifungals; Candida glabrata; Colonization; PAFE; Virulence

Indexed keywords

AMPHOTERICIN B; FLUCYTOSINE; KETOCONAZOLE; NYSTATIN; ANTIFUNGAL AGENT;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOFILM; CANDIDA GLABRATA; CELL SURFACE; CONTROLLED STUDY; EPITHELIUM CELL; EXPOSURE; FUNGAL COLONIZATION; FUNGUS ISOLATION; HYDROPHOBICITY; IN VITRO STUDY; NONHUMAN; BIOMASS; CANDIDIASIS; CELL ADHESION; CELL WALL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; PATHOGENICITY; PHOTOMETRY;

CANDIDA; CANDIDA GLABRATA;

AMPHOTERICIN B; ANTIFUNGAL AGENTS; BIOFILMS; BIOMASS; CANDIDA GLABRATA; CANDIDIASIS; CELL ADHESION; CELL WALL; EPITHELIAL CELLS; FLUCYTOSINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KETOCONAZOLE; NEPHELOMETRY AND TURBIDIMETRY; NYSTATIN;

EID: 77954810938     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693780903496583     Document Type: Article

References (30)

1. Krcmery V, Barnes AJ. Non-a lbicans Candida spp. causing fungaemia pathogenicity and antifungal resistance. J Hosp Infect 2002; 50 : 243-260.
2. Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 2007; 20 : 133-163.
3. Lichtenstern C, Nguyen TH, Schemmer P, Hoppe-Tichy T, Weigand MA. Efficacy of caspofungin in invasive candidiasis and candidemia - de-escalation strategy. Mycoses 2008; 51 : 35-46.
4. Ruhnke M, Hartwig K, Kofia G. New options for treatment of candidaemia in critically ill patients. Clin Microbiol Infect 2008; 14 : 46-54.
5. Pfaller MA, Messer SA, Boyken L, et al . Geographic variation in the susceptibilities of invasive isolates of Candida glabrata to seven systemically active antifungal agents: a global assessment from the ARTEMIS Antifungal Surveillance Program conducted in 2001 and 2002. J Clin Microbiol 2004; 42 : 3142-3146.
6. Sanguinetti M, Posteraro B, Fiori B, e t al . Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance. Antimicrob Agents Chemother ; 2005; 49 : 668-679.
7. Posteraro B, Sanguinetti M, Fiori B, et al . Caspofungin activity against clinical isolates of azole cross-resistant Candida glabrata overexpressing effl ux pump genes. J Antimicrob Chemother 2006; 58 : 458-461.
8. Ito JI, Hooshmand-Rad R. Treatment of Candida infections with amphotericin B lipid complex. Clin Infect Dis 2005; 40 : 384-391.
9. Ellepola ANB, Samaranayake LP. Oral candidal infections and antimycotics. Crit Rev Oral Biol Med 2000; 11 : 172-198.
10. Turnidge JD, Gudmundsson S, Vogelman B, Craig WA. The postantibiotic effect of antifungal agents against common pathogenic yeasts. J Antimicrob Chemother 1994; 34 : 83-92.
11. Craig WA, Gudmundsson S. The postantibiotic effect. In: Lorian V. (ed). Antibiotics in Laboratory Medicine . Baltimore: Williams & Wilkins, 1996: 403-431.
12. Egusa H, Ellepola ANB, Nikawa H, Hamada T, Samaranayake LP. Sub-therapeutic exposure to polyene antimycotics elicits a postantifungal effect (PAFE) and depresses the cell-surface-hydrophobicity of oral Candida albicans isolates. J Oral Pathol Med 2000; 29 : 206-213.
13. Ellepola ANB, Panagoda GJ, Samaranayake LP. Adhesion of oral Candida species to human buccal epithelial cells following brief exposure to nystatin. Oral Microbiol Immunol 1999; 14 : 358-363.
14. Lyon, JP, Aparecida de Resende M. Evaluation of adhesion to buccal epithelial cells in Candida species obtained from denture wearers after exposure to fl uconazole. Mycoses 2006; 50 : 21-24.
15. Clancy CJ, Huang H, Cheng S, Derendorf H, Nguyen MH. Characterizing the effects of caspofungin on Candida albicans , Candida parapsilosis , and Candida glabrata isolates by simultaneous time-kill and postantifungal-effect experiments. Antimicrob Agents Chemother 2006; 50 : 2569-2572.
16. Silverman Jr S, Migliorati CA, Epstein JB, Samaranayake LP. Laboratory diagnosis of oral candidosis, p. 213-237. In: Samaranayake L. P., MacFarlane T. W. (eds). Oral Candidiasis . London, England: Wright-Butterworth, 1990.
17. McGinnis MR, Rinaldi MG. Antifungal drugs: mechanisms of action, drug resistance, susceptibility testing and assays of activity in biological fl uids, p.176-211. In: Lorian V. (ed) Antibiotics in Laboratory Medicine . Baltimore: Williams & Wilkins, 1996.
18. Löwdin E, Odenholt-Tornqvist I, Bengtsson S, Cars O. A new method to determine postantibiotic effect and effects of subinhibitory antibiotic concentrations. Antimicrob Agents Chemother 1993; 37 : 2200-2205.
19. Kimura LH, Pearsall NN. Adherence of C. albicans to human buccal epithelial cells. Infect Immun 1978; 21 : 64-68.
20. Sweet SP, MacFarlane TW, Samaranayake LP. Determination of the cell-surface-hydrophobicity of oral bacteria using a modified hydrocarbon adherence method. FEMS Microbiol Lett 1987; 48 : 159-163.
21. Samaranayake LP, MacFarlane TW. An i n vitro study of the adherence of C. albicans to acrylic surfaces. Arch Oral Biol 1980; 25 : 603-609.
22. Jin Y, Yip HK, Samaranayake YH, Yau JY, Samaranayake LP. Biofilm forming ability of Candida albicans is unlikely to contribute to high oral yeast carriage in human immunodeficiency virus-infection. J Clin Microbiol 2003; 41 : 2961-2967.
23. Garcia MT, Llorente MT, Minguez F, Prieto J. Infl uence of temperature and concentration on the postantifungal effect and the effects of sub-MIC concentrations of four antifungal agents on previously treated Candida species. Chemotherapy 2000; 46 : 245-252 (Pubitemid 30428838)
24. Dorocka-Bobkowska B, Konopka K, Dügües N. Infl uence of antifungal polyenes on the adhesion of Candida albicans and Candida glabrata to human epithelial cells in vitro . Arch Oral Biol 2003; 48 : 805-814.
25. Samaranayake YH, Wu PC, Samaranayake LP, So M. Relationship between the cell-surface-hydrophobicity and adherence of Candida krusei and Candida albicans to epithelial and denture acrylic surfaces. APMIS 1995; 103 : 707-713
26. Panagoda GJ, Ellepola ANB, Samaranayake LP. Adhesion to denture acrylic surfaces and relative cell-surface-hydrophobicity of C. parapsilosis and C. albicans . APMIS 1998; 106 : 736-742.
27. Luo G, Samaranayake LP. C andida glabrata , an emerging fungal pathogen, exhibits superior relative cell-surface-hydrophobicity and adhesion to denture acrylic surfaces compared with Candida albicans . APMIS 2002; 110 : 601-610.
28. Hazen KC, Hazen BW. Hydrophobic surface protein masking by the opportunistic fungal pathogen C. albicans . Infect Immun 1992; 60 : 1499-1508.
29. Shibl AM, Ramadan MA, Tawfik AF. Post-antibiotic effect of roxithromycin on streptolysin production, hydrophobicity and bactericidal activity of PMNL by Streptococcus pyogenes . Diagn Microbiol Infect Dis 1994; 20 : 7-11.
30. Cross LJ, Bagg J, Aitchison TC. Efficacy of the cyclodextrin liquid preparation of itraconazole in treatment of denture stomatitis: comparison with itraconazole capsules. Antimicrob Agents Chemother 2000; 44 : 425-427.