Assessment of diagnostic competence of plasmatic androgens on polycystic ovary syndrome based on receiver operator characteristic curves

Gynecological Endocrinology

Volumn 26, Issue 8, 2010, Pages 600-606

  Villarroel, Claudio ^a   Trejo, León ^a   Muñoz, Alex ^a   Kohen, Paulina ^a   Fuentes, Ariel ^a   Devoto, Luigi ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

androgen levels; hyperandrogenism; Polycystic ovary syndrome; receiver operator characteristic curves

Indexed keywords

AMMONIUM SULFATE; ANDROGEN; ANDROSTENEDIONE; PRASTERONE SULFATE; TESTOSTERONE; BIOLOGICAL MARKER;

ADULT; ANALYTIC METHOD; ARTICLE; COMPETENCE; DIAGNOSTIC ERROR; DIAGNOSTIC VALUE; FEMALE; HORMONAL REGULATION; HUMAN; HYPERANDROGENISM; MAJOR CLINICAL STUDY; OVARY POLYCYSTIC DISEASE; PHENOTYPE; PRECIPITATION; PRIORITY JOURNAL; BLOOD; CASE CONTROL STUDY; COMPARATIVE STUDY; POLYCYSTIC OVARY SYNDROME; RECEIVER OPERATING CHARACTERISTIC;

ADULT; ANDROGENS; ANDROSTENEDIONE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; HUMANS; POLYCYSTIC OVARY SYNDROME; ROC CURVE; TESTOSTERONE;

EID: 77954804074     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513591003686346     Document Type: Article

References (35)

1. Carmina E, Azziz R, Diagnosis, phenotype, and prevalence of polycystic ovary syndrome. Fertil Steril 2006;86(Suppl 1): S7-S8.
2. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro R, Norman RJ, Taylor A, Witchel S. The Androgen excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 2009;91:456-488.
3. Zawasdki JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome: towards a rational approach, In: Dunaif A, Givens JR, Haseltine FP, Merrian GR, editors. Polycystic ovary syndrome. Boston, MA: Blackwell Scientific Publications; 1992. pp 377-384.
4. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004;19:41-47.
5. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro R, Norman RJ, Taylor A, Witchel S. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. J Clin Endocrinol Metab 2006;91:4237-4245.
6. Balen AH, Laven JS, Tan SL, Dewailly D. Ultrasound assessment of the polycystic ovary: international consensus definitions. Hum Reprod Update 2003;9:505-514.
7. Jonard S, Robert Y, Cortet-Rudelli C, Pigny P, Decanter C, Dewailly D. Ultrasound examination of polycystic ovaries: is it worth counting the follicles? Hum Reprod 2003;18:598-603.
8. Jonard S, Dewailly D. The follicular excess in polycystic ovaries, due to intra-ovarian hyperandrogenism, may be the main culprit for the follicular arrest. Hum Reprod Update 2004;10:107-117.
9. Jonard S, Robert Y, Dewailly D. Revisiting the ovarian volume as a diagnostic criterion for polycystic ovaries. Hum Reprod 2005;20:2893-2898.
10. Legro RS, Chiu P, Kunselman AR, Bentley CM, Dodson WC, Dunaif A. Polycystic ovaries are common in women with hyperandrogenic chronic anovulation but do not predict metabolic or reproductive phenotype. J Clin Endocrinol Metab 2005;90:2571-2579. (Pubitemid 40686293)
11. Stein IF, Leventahl ML. Amenorrhea associated with polycystic ovaries. Am J Obstet Gynecol 1935;29:181-191.
12. Azziz, R. Androgen excess is the key element in polycystic ovary syndrome. Fertil Steril 2003;80:252-254.
13. Davison SL, Davis SR. Androgens in women. J Steroid Biochem Mol Biol 2003;85:363-366.
14. Davison SL, Bell R. Androgen physiology. Semin Reprod Med 2006;24:71-77.
15. Dechaud H, Lejeune H, Garoscio-Cholet M, Mallein R, Pugeat M. Radioimmunoassay of testosterone not bound to sex-steroid-binding protein in plasma. Clin Chem 1989;35: 1609-1614.
16. Rosner W. Errors in the measurement of plasma free testosterone. J Clin Endocrinol Metab 1997;82:2014-2015.
17. Stanczyk FZ. Measurement of androgens in women. Semin Reprod Med 2006;24:78-85.
18. Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999;84:3666-3672.
19. Carmina E. Prevalence of idiopathic hirsutism. Eur J Endocrinol 1998;139:421-423.
20. Boots LR, Potter S, Potter D, Azziz R. Measurement of total serum testosterone levels using commercially available kits: high degree of between-kit variability. Fertil Steril 1998;69: 286-292.
21. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998;83:3078-3082.
22. Zweig MH, ROC plots display test accuracy, but are still limited by the study design. Clin Chem 1993;39:1345-1346.
23. Asuncion M, Calvo RM, San Millan JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab 2000;85:2434-2438.
24. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004;89:2745-2749.
25. Zweig MH, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 1993;39:561-577
26. Tremblay RR, Dube JY, Plasma concentrations of free and non-TeBG bound testosterone in women on oral contraceptives. Contraception 1974;10:599-605.
27. Adams J, Polson DW, Franks S. reference (33): Sufi, S.B., Donaldson, A and Jeffcoate. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. BrMed J 1986;293:355-359.
28. Sir-Petermann T, Devoto L, Maliqueo M, Peirano P, Recabarren SE, Wildt L. Resumption of ovarian function during lactational amenorrhoea in breastfeeding women with polycystic ovarian syndrome: endocrine aspects. Hum Reprod 2001;16:1603-1610. (Pubitemid 32761738)
29. DeUgarte CM, Woods KS, Bartolucci AA, Azziz R. Degree of facial and body terminal hair growth in unselected black and white women: toward a populational definition of hirsutism. J Clin Endocrinol Metab 2006;91:1345-1350.
30. Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961;21:1440-1447.
31. Chang PL, Lindheim SR, Lowre C, Ferin M, Gonzalez F, Berglund L, Carmina E, Sauer MV, Lobo RA. Normal ovulatory women with polycystic ovaries have hyperandrogenic pituitary-ovarian responses to gonadotropin-releasing hormone-agonist testing. J Clin Endocrinol Metab 2000;85: 995-1000.
32. Skalba P, Wojtowicz M, Sikora J. Androgen and SHBG serum concentrations in late post-menopause women. Med Sci Monit 2003;9:CR152-CR156.
33. Sufi SB, Donaldson A, Jeffcoate SL. WHO special programme of research, development and training in human reproduction. WHO matched reagent programme steroid radioimmunoassay. 22nd ed. Method Manual. London: World Health Organization; 1998.
34. Cumming DC, Wall SR. Non-sex hormone-binding globulinbound testosterone as a marker for hyperandrogenism. J Clin Endocrinol Metab 1985;61:873-876.
35. Gilling-Smith C, Willis DS, Beard RW, Franks S. Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries. J Clin Endocrinol Metab 1994;79:1158-1165.