Ginsenoside-Rg1 inhibits cell apoptosis induced by beta amyloid

National Medical Journal of China

Volumn 88, Issue 25, 2008, Pages 1763-1766

  Wei, Cui Bai ^a   Jia, Jian Ping ^b   Liang, Ping ^b   Guan, Yun Qian ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

Amyloid beta protein; Apoptosis; Caspase 3

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; ANNEXIN; CASPASE 3; GINSENOSIDE RG 1; GINSENOSIDE;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; FEMALE; GENE MUTATION; GENETIC TRANSFECTION; HAMSTER; IMMUNOFLUORESCENCE; INHIBITION KINETICS; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; STAINING; SURVIVAL RATE; WESTERN BLOTTING; WILD TYPE; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; CRICETULUS; DOSE RESPONSE; METABOLISM; MUTATION; RANDOMIZATION; TUMOR CELL LINE;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GINSENOSIDES; MUTATION; RANDOM ALLOCATION;

EID: 77954790023     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Vassar R. Beta-Secretase. APP and Abeta in Alzheimer's disease. Subcell Biochem, 2005,38:79-103.
2. Yun TK. Panax ginseng- a non-organ-specific cancer preventive? Lancet Oncol, 2001,2:49-54.
3. Kawasumi M, Hashimoto Y, Chiba T, et al. Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevent insults. Neurosignals, 2002,11:236-250. (Pubitemid 37494391)
4. Carter J, Lippa CF. Beta-amyloid, neuronal death and Alzheimer's disease. Curr Mol Med, 2001,1:733-737. (Pubitemid 33772946)
5. Terro F, Czech C, Esclaire F, et al. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress. J Neurosci Res, 2002,69:530-539.
6. Mouser PE, Head E, Ha KH, et al. Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain. Am J Pathol, 2006,168:936-946.