Effect of gentamicin-absorbed collagen in wound healing in pilonidal sinus surgery: A prospective randomized study

Journal of International Medical Research

Volumn 38, Issue 3, 2010, Pages 1029-1033

  Yetim, I ^a   Ozkan, O V ^a   Dervisoglu A ^b   Erzurumlu, K ^c   Canbolant, E ^a  

^a MUSTAFA KEMAL UNIVERSITY   (Turkey)

^b Medicalpark Private Hospital   (Turkey)

^c ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Antibiotics; Gentamicin absorbed collagen; Length of hospital stay; Pilonidal surgery; Post operative wound healing

Indexed keywords

CIPROFLOXACIN; COLLAGEN; GENTACOLL; GENTAMICIN; ORNIDAZOLE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; DRUG IMPLANT;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG IMPLANTATION; EXCISION; HEALING IMPAIRMENT; HOSPITALIZATION; HUMAN; LENGTH OF STAY; LOCAL ANESTHESIA; MAJOR CLINICAL STUDY; PILONIDAL SINUS; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; SURGICAL APPROACH; SURGICAL INFECTION; SURGICAL WOUND; WOUND CLOSURE; WOUND HEALING; DRUG IMPLANT; ORAL DRUG ADMINISTRATION; PATHOLOGY; PROSPECTIVE STUDY; SURGICAL SPONGE; SURGICAL WOUND INFECTION; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANTI-BACTERIAL AGENTS; COLLAGEN; DRUG IMPLANTS; GENTAMICINS; HUMANS; LENGTH OF STAY; PILONIDAL SINUS; PROSPECTIVE STUDIES; SURGICAL SPONGES; SURGICAL WOUND INFECTION; TREATMENT OUTCOME; WOUND HEALING;

EID: 77954783717     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800329     Document Type: Article

References (17)

1. Sondenaa K, Andersen E, Nesvik I, et al: Patient characteristics and symptoms in chronic pilonidal sinus disease. Int J Colorectal Dis 1995; 10: 39-42.
2. Allen-Mersh TG: Pilonidal sinus: finding the right track for treatment. Br J Surg 1990; 77: 123-132.
3. Spivak H, Brooks VL, Nussbaum M, et al: Treatment of chronic pilonidal disease. Dis Colon Rectum 1996; 39: 1136-1139.
4. Søndenaa K, Anderson E, Søreide JA: Morbidity and short term results in a randomised trial of open compared to closed treatment of chronic pilonidal sinus. Eur J Surg 1992; 158: 351-355.
5. Chintapatla S, Safarani N, Kumar S, et al: Sacrococcygeal pilonidal sinus: historical review, pathological insight and surgical options. Tech Coloproctol 2003; 7: 3-8.
6. Aydede H, Erhan Y, Sakarya A, et al: Comparison of three methods in surgical treatment of pilonidal disease. Aust NZ J Surg 2001; 71: 362-364.
7. Khaira HS, Brown JH: Excision and primary suture of pilonidal sinus. Ann R Coll Surg Engl 1995; 77: 242-244.
8. Iesalnieks I, Furst A, Rentsch M, et al: Primary midline closure after excision of a pilonidal sinus is associated with a high recurrence rate. Chirurg 2003; 74: 461-468 [in German].
9. Abdul-Ghani AK, Abdul-Ghani AN, Ingham Clark CL: Day-care surgery for pilonidal sinus. Ann R Coll Surg Engl 2006; 88: 656-658.
10. Gado FJ: Effectiveness of collagen-gentamicin implant for treatment of 'dirty' abdominal wounds. World J Surg 1999; 23: 123-126.
11. Rutten HJ, Nijhuis PH: Prevention of wound infection in elective colorectal surgery by local application of a gentamicin containing collagen sponge. Eur J Surg Suppl 1997; 578: 31-35.
12. Rosen HR, Marczell AP, Czerwenka E, et al: Local gentamicin application for perineal wound healing following abdominoperineal rectum excision. Am J Surg 1991; 162: 438-441.
13. Gruessner U, Clemens M, Pahlplatz PV, et al: Improvement of perineal wound healing by local administration of gentamicin-impregnated collagen fleeces after abdominoperineal excision of rectal cancer. Am J Surg 2001; 182: 502-509.
14. Musella M, Guido A, Musella S: Collagen tampons as aminoglycoside carriers to reduce postoperative infection rate in prosthetic repair of groin hernias. Eur J Surg 2001; 167: 130-132.
15. ®) after surgical treatment of a pilonidal sinus. Colorectal Dis 2003; 5: 222-227.
16. Vogel P, Lenz J: Treatment of pilonidal sinus with excision and primary suture using a local, resorbable antibiotic carrier. Results of a prospective randomized study. Chirurg 1992; 63: 748-753 [in German].
17. Friberg O, Svedjeholm R, Söderquist B, et al: Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. Ann Thorac Surg 2005; 79: 153-162.