Ligand-dependent conformation change reflects steric structure and interactions of a vitamin D receptor/ligand complex: A fragment molecular orbital study

Journal of Steroid Biochemistry and Molecular Biology

Volumn 121, Issue 1-2, 2010, Pages 56-59

  Motoyoshi, Sayaka ^a   Yamagishi, Kenji ^a   Yamada, Sachiko ^a,b   Tokiwa, Hiroaki ^a,b  

^a RIKKYO UNIVERSITY   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

1 ,25 Dihydroxy 19 nor vitamin D3; Conformation changes; Fragment molecular orbital method; Receptor ligand interaction analysis

Indexed keywords

AMINO ACID; COLECALCIFEROL; ISOLEUCINE; LIGAND; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR; PROTEIN BINDING;

ACCURACY; ARTICLE; COMPUTER MODEL; CONFORMATION; CRYSTAL STRUCTURE; ELECTRONICS; FRAGMENT MOLECULAR ORBITAL; HYDROPHILICITY; HYDROPHOBICITY; LIGAND BINDING; METHODOLOGY; MOLECULAR INTERACTION; QUANTUM CHEMISTRY; ALGORITHM; CHEMICAL PHENOMENA; CHEMISTRY; COMPUTER SIMULATION; DRUG DESIGN; HUMAN; MEDICINAL CHEMISTRY; PROCEDURES; STATIC ELECTRICITY; STEREOISOMERISM; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; HYDROPHOBICITY; ISOLEUCINE; LIGANDS; MOLECULAR CONFORMATION; PROTEIN BINDING; RECEPTORS, CALCITRIOL; STATIC ELECTRICITY; STEREOISOMERISM; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;

EID: 77954762856     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.03.024     Document Type: Article

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