A novel nonsecosteroidal VDR agonist (CH5036249) exhibits efficacy in a spontaneous benign prostatic hyperplasia beagle model

Journal of Steroid Biochemistry and Molecular Biology

Volumn 121, Issue 1-2, 2010, Pages 204-207

  Taniguchi, K ^a   Katagiri, K ^b   Kashiwagi, H ^a   Harada, S ^a   Sugimoto, Y ^b   Shimizu, Y ^b   Arakawa, H ^b   Ito, T ^b   Yamazaki, M ^a   Watanabe, T ^a   Kato, A ^a   Hoshino, E ^b   Takahashi, T ^a   Esaki, T ^a   Suzuki, M ^a   Takeda, S ^a   Ichikawa, F ^a   Harada, A ^a   Sekiguchi, N ^a   Ishigai, M ^a   Kawata, H ^a   Yoneya, T ^a   Onuma, E ^a   Sudoh, M ^a   Aoki, Y ^a   more..

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b Chugai Research Institute for Medical Science Inc   (Japan)

Author keywords

Nonsecosteroidal vitamin D receptor agonist; Prostate stromal cells; Spontaneous benign prostatic hyperplasia

Indexed keywords

1,25 DIHYDROXYERGOCALCIFEROL; CALCIUM; CH 5036249; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; BENZHYDRYL DERIVATIVE; CALCITRIOL RECEPTOR; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM BLOOD LEVEL; CELL GROWTH; CONTROLLED STUDY; DOG; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG STRUCTURE; HISTOLOGY; HUMAN; HUMAN CELL; MALE; NONHUMAN; PROSTATE HYPERTROPHY; STROMA CELL; AGONISTS; ANIMAL; BIOLOGICAL MODEL; BLOOD; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MICRONUCLEUS TEST; PATHOLOGY; PROSTATE; RAT;

ANIMALS; BENZHYDRYL COMPOUNDS; CALCIUM; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MICRONUCLEUS TESTS; MODELS, BIOLOGICAL; PROSTATE; PROSTATIC HYPERPLASIA; PYRIDINES; RATS; RECEPTORS, CALCITRIOL; STROMAL CELLS;

ANIMALIA; CANIS FAMILIARIS; RATTUS;

EID: 77954757242     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.03.043     Document Type: Article

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