Chronic norovirus infection after kidney transplantation: Molecular evidence for immune-driven viral evolution

Clinical Infectious Diseases

Volumn 51, Issue 3, 2010, Pages 307-314

  Schorn, Robert ^a   Höhne, Marina ^c   Meerbach, Astrid ^b   Bossart, Walter ^b   Wüthrich, Rudolf P ^a   Schreier, Eckart ^c   Müller, Nicolas J ^a   Fehr, Thomas ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AZATHIOPRINE; CALCINEURIN INHIBITOR; CYCLOSPORIN A; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY; VIRUS RNA;

ADULT; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; DIARRHEA; DISEASE COURSE; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FECES ANALYSIS; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; GENE MUTATION; GRAFT RECIPIENT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; MOLECULAR EVOLUTION; NOROVIRUS; NUCLEOTIDE SEQUENCE; OUTPATIENT DEPARTMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VIRAL GASTROENTERITIS; VIRUS CAPSID; VIRUS ISOLATION; VIRUS SHEDDING; VIRUS STRAIN; VIRUS TRANSMISSION; CALICIVIRIDAE INFECTIONS; CLASSIFICATION; CLUSTER ANALYSIS; DNA SEQUENCE; GENETICS; IMMUNOCOMPROMISED PATIENT; IMMUNOLOGY; ISOLATION AND PURIFICATION; MIDDLE AGED; MOLECULAR GENETICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; VIROLOGY;

ADULT; CALICIVIRIDAE INFECTIONS; CHRONIC DISEASE; CLUSTER ANALYSIS; DIARRHEA; EVOLUTION, MOLECULAR; FEMALE; HUMANS; IMMUNOCOMPROMISED HOST; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NOROVIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY;

EID: 77954748230     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/653939     Document Type: Article

References (30)

1. Zheng DP, Ando T, Fankhauser RL, Beard RS, Glass RI, Monroe SS. Norovirus classification and proposed strain nomenclature. Virology 2006; 346(2):312-323.
2. Siebenga JJ, Vennema H, Renckens B, et al. Epochal evolution ofGGII.4 norovirus capsid proteins from 1995 to 2006. J Virol 2007; 81(18): 9932-9941.
3. Lindesmith LC, Donaldson EF, Lobue AD, et al. Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med 2008; 5(2):e31.
4. Lopman B, Vennema H, Kohli E, et al. Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant. Lancet 2004; 363(9410):682-688.
5. Marks PJ, Vipond IB, Regan FM, Wedgwood K, Fey RE, Caul EO. A school outbreak of Norwalk-like virus: evidence for airborne transmission. Epidemiol Infect 2003; 131(1):727-736.
6. Rockx B, De Wit M, Vennema H, et al. Natural history of human calicivirus infection: a prospective cohort study. Clin Infect Dis 2002; 35(3):246-253.
7. Dolin R, Reichman RC, Roessner KD, et al. Detection by immune electron microscopy of the Snow Mountain agent of acute viral gastroenteritis. J Infect Dis 1982; 146(2):184-189.
8. Chan MC, Sung JJ, Lam RK, et al. Fecal viral load and norovirusassociated gastroenteritis. Emerg Infect Dis 2006; 12(8):1278-1280.
9. Atmar RL, Opekun AR, Gilger MA, et al. Norwalk virus shedding after experimental human infection. Emerg Infect Dis 2008; 14(10):1553-1557.
10. Siebenga JJ, Beersma MF, Vennema H, van Biezen P, Hartwig NJ, Koopmans M. High prevalence of prolonged norovirus shedding and illness among hospitalized patients: a model for in vivo molecular evolution. J Infect Dis 2008; 198(7):994-1001.
11. Kaufman SS, Chatterjee NK, Fuschino ME, et al. Calicivirus enteritis in an intestinal transplant recipient. Am J Transplant 2003; 3(6):764-768.
12. Lee BE, Pang XL, Robinson JL, Bigam D, Monroe SS, Preiksaitis JK. Chronic norovirus and adenovirus infection in a solid organ transplant recipient. Pediatr Infect Dis J 2008; 27(4):360-362.
13. Florescu DF, Hill LA, McCartan MA, Grant W. Two cases of Norwalk virus enteritis following small bowel transplantation treated with oral human serum immunoglobulin. Pediatr Transplant 2008; 12(3):372-375.
14. Ludwig A, Adams O, Laws HJ, Schroten H, Tenenbaum T. Quantitative detection of norovirus excretion in pediatric patients with cancer and prolonged gastroenteritis and shedding of norovirus. J Med Virol 2008; 80(8):1461-1467.
15. Nilsson M, Hedlund KO, Thorhagen M, et al. Evolution of human calicivirus RNA in vivo: accumulation of mutations in the protruding P2 domain of the capsid leads to structural changes and possibly a new phenotype. J Virol 2003; 77(24):13117-13124.
16. Westhoff TH, Vergoulidou M, Loddenkemper C, et al. Chronic norovirus infection in renal transplant recipients. Nephrol Dial Transplant 2009; 24(3):1051-1053.
17. Hohne M, Schreier E. Detection and characterization of norovirus outbreaks in Germany: application of a one-tube RT-PCR using a fluorogenic real-time detection system. J Med Virol 2004; 72(2):312-319.
18. Vinje J, Hamidjaja RA, Sobsey MD. Development and application of a capsid VP1 (region D) based reverse transcription PCR assay for genotyping of genogroup I and II noroviruses. J Virol Methods 2004; 116(2):109-117.
19. Oh DY, Gaedicke G, Schreier E. Viral agents of acute gastroenteritis in German children: prevalence and molecular diversity. J Med Virol 2003; 71(1):82-93.
20. Allen DJ, Gray JJ, Gallimore CI, Xerry J, Iturriza-Gomara M. Analysis of amino acid variation in the P2 domain of the GII-4 norovirus VP1 protein reveals putative variant-specific epitopes. PLoS One 2008; 3(1): e1485.
21. Kirkwood CD, Streitberg R. Calicivirus shedding in children after recovery from diarrhoeal disease. J Clin Virol 2008; 43(3):346-348.
22. Davidson MM, Sood VP, Ho-Yen DO. Small round virus excretion in long-stay geriatric patients. J Med Virol 1993; 41(3):256-259.
23. Sato K, Amada N, Sato T, et al. Severe elevations of FK506 blood concentration due to diarrhea in renal transplant recipients. Clin Transplant 2004; 18(5):585-590.
24. Asano T, Nishimoto K, Hayakawa M. Increased tacrolimus trough levels in association with severe diarrhea, a case report. Transplant Proc 2004; 36(7):2096-2097.
25. Wu HM, Fornek M, Schwab KJ, et al. A norovirus outbreak at a longterm- care facility: the role of environmental surface contamination. Infect Control Hosp Epidemiol 2005; 26(10):802-810.
26. Gallimore CI, Taylor C, Gennery AR, et al. Contamination of the hospital environment with gastroenteric viruses: comparison of two pediatric wards over a winter season. Journal of clinical microbiology 2008; 46(9):3112-3115.
27. Xerry J, Gallimore CI, Iturriza-Gomara M, Gray JJ. Tracking the transmission routes of genogroup II noroviruses in suspected food-borne or environmental outbreaks of gastroenteritis through sequence analysis of the P2 domain. J Med Virol 2009; 81(7):1298-1304.
28. Cao S, Lou Z, Tan M, et al. Structural basis for the recognition of blood group trisaccharides by norovirus. J Virol 2007; 81(11):5949-5957.
29. Allen DJ, Noad R, Samuel D, Gray JJ, Roy P, Iturriza-Gomara M. Characterisation of a GII-4 norovirus variant-specific surface-exposed site involved in antibody binding. Virol J 2009; 6:150.
30. Donaldson EF, Lindesmith LC, Lobue AD, Baric RS. Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations. Immunol Rev 2008; 225:190-211.