Toll-like receptor 4 polymorphisms in German and US patients are not associated with occurrence or severity of acute pancreatitis

Gut

Volumn 59, Issue 8, 2010, Pages 1154-1155

  Guenther, Annett ^a   Aghdassi, Ali ^a   Muddana, Venkata ^b   Rau, Bettina ^c   Schulz, Hans Ulrich ^a   Mayerle, Julia ^a   Kraft, Matthias ^a   Whitcomb, David C ^b   Lerch, Markus M ^a   Weiss, Frank U ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 4;

ACUTE PANCREATITIS; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; ETHNIC DIFFERENCE; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GERMANY; HUMAN; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK ASSESSMENT; UNITED STATES;

ACUTE DISEASE; CASE-CONTROL STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTATION; PANCREATITIS; TOLL-LIKE RECEPTOR 4;

EID: 77954738277     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2009.192492     Document Type: Letter

References (4)

1. Sharif R, Dawra RK, Wasiluk K, et al. Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice. Gut 2009;58:813-19.
2. Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000;25:187-91. (Pubitemid 30394990)
3. Zhang DL, Zheng HM, Zhou YB, et al. TLR and MBL gene polymorphisms in severe acute pancreatitis. Mol Diagn Ther 2008;12:45-50.
4. Hofner P, Balog A, Gyulai Z, et al. Polymorphism in the IL-8 gene, but not in the TLR4 gene, increases the severity of acute pancreatitis. Pancreatology 2006;6:542-8. (Pubitemid 46360712)