-
1
-
-
34247270770
-
Phase III trial comparing doxorubicin plus cyclophosphamide with docetaxel plus cyclophosphamide as adjuvant therapy for operable breast cancer
-
Jones SE, Savin MA, Holmes FA, O'Shaughnessy JA, Blum JL, Vukelja S, et al. Phase III trial comparing doxorubicin plus cyclophosphamide with docetaxel plus cyclophosphamide as adjuvant therapy for operable breast cancer. J Clin Oncol. 2006;24:5381-7.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5381-5387
-
-
Jones, S.E.1
Savin, M.A.2
Holmes, F.A.3
O'Shaughnessy, J.A.4
Blum, J.L.5
Vukelja, S.6
-
2
-
-
0030014783
-
DNA topoisomerases
-
Wang JC. DNA topoisomerases. Annu Rev Biochem. 1996;65:635-92.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 635-692
-
-
Wang, J.C.1
-
3
-
-
0027292407
-
DNA topoisomerase I and II as targets for rational design of new anticancer drugs
-
Cummings J, Smyth JF. DNA topoisomerase I and II as targets for rational design of new anticancer drugs. Ann Oncol. 1993;4:533-43.
-
(1993)
Ann Oncol
, vol.4
, pp. 533-543
-
-
Cummings, J.1
Smyth, J.F.2
-
4
-
-
2942521162
-
Proliferation markers predictive of the pathological response and disease outcome of patients with breast carcinomas treated by anthracycline-based preoperative chemotherapy
-
Vincent-Salomon A, Rousseau A, Jouve M, Beuzeboc P, Sigal- Zafrani B, Freneaux P, et al. Proliferation markers predictive of the pathological response and disease outcome of patients with breast carcinomas treated by anthracycline-based preoperative chemotherapy. Eur J Cancer. 2004;40:1502-8.
-
(2004)
Eur J Cancer
, vol.40
, pp. 1502-1508
-
-
Vincent-Salomon, A.1
Rousseau, A.2
Jouve, M.3
Beuzeboc, P.4
Sigal-, Z.B.5
Freneaux, P.6
-
5
-
-
0033050164
-
Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy
-
Kuerer HM, Newman LA, Smith TL, Ames FC, Hunt KK, Dhingra K, et al. Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy. J Clin Oncol. 1999;17:460-9.
-
(1999)
J Clin Oncol
, vol.17
, pp. 460-469
-
-
Kuerer, H.M.1
Newman, L.A.2
Smith, T.L.3
Ames, F.C.4
Hunt, K.K.5
Dhingra, K.6
-
6
-
-
33745670605
-
Primary systemic therapy of breast cancer
-
Sachelarie I, Grossbard ML, Chadha M, Feldman S, Ghesani M, Blum RH. Primary systemic therapy of breast cancer. Oncologist. 2006;11:574-89.
-
(2006)
Oncologist
, vol.11
, pp. 574-589
-
-
Sachelarie, I.1
Grossbard, M.L.2
Chadha, M.3
Feldman, S.4
Ghesani, M.5
Blum, R.H.6
-
7
-
-
0028023408
-
Expression of P-glycoprotein and in vitro or in vivo resistance to doxorubicin and cisplatin in breast and ovarian cancers
-
Veneroni S, Zaffaroni N, Daidone MG, Benini E, Villa R, Silvestrini R. Expression of P-glycoprotein and in vitro or in vivo resistance to doxorubicin and cisplatin in breast and ovarian cancers. Eur J Cancer. 1994;30A:1002-7.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 1002-1007
-
-
Veneroni, S.1
Zaffaroni, N.2
Daidone, M.G.3
Benini, E.4
Villa, R.5
Silvestrini, R.6
-
8
-
-
0033971806
-
TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients
-
Kandioler-Eckersberger D, Ludwig C, Rudas M, Kappel S, Janschek E, Wenzel C, et al. TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Clin Cancer Res. 2000;6:50-6.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 50-56
-
-
Kandioler-Eckersberger, D.1
Ludwig, C.2
Rudas, M.3
Kappel, S.4
Janschek, E.5
Wenzel, C.6
-
9
-
-
0034662602
-
Deregulated manganese superoxide dismutase expression and resistance to oxidative injury in p53-deficient cells
-
Pani G, Bedogni B, Anzevino R, Colavitti R, Palazzotti B, Borrello S, et al. Deregulated manganese superoxide dismutase expression and resistance to oxidative injury in p53-deficient cells. Cancer Res. 2000;60:4654-60.
-
(2000)
Cancer Res
, vol.60
, pp. 4654-4660
-
-
Pani, G.1
Bedogni, B.2
Anzevino, R.3
Colavitti, R.4
Palazzotti, B.5
Borrello, S.6
-
10
-
-
0043129024
-
Induction chemotherapy for breast carcinoma: Predictive markers and relation with outcome
-
Penault-Llorca F, Cayre A, Bouchet Mishellany F, Amat S, Feillel V, Le Bouedec G, et al. Induction chemotherapy for breast carcinoma: predictive markers and relation with outcome. Int J Oncol. 2003;22:1319-25.
-
(2003)
Int J Oncol
, vol.22
, pp. 1319-1325
-
-
Penault-Llorca, F.1
Cayre, A.2
Bouchet, M.F.3
Amat, S.4
Feillel, V.5
Le Bouedec, G.6
-
11
-
-
0037333625
-
Topoisomerase II-alpha (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy
-
Park K, Kim J, Lim S, Han S. Topoisomerase II-alpha (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy. Eur J Cancer. 2003;39:631-4.
-
(2003)
Eur J Cancer
, vol.39
, pp. 631-634
-
-
Park, K.1
Kim, J.2
Lim, S.3
Han, S.4
-
12
-
-
33646681444
-
National cancer institute of Canada clinical trials group. HER2 and responsiveness of breast cancer to adjuvant chemotherapy
-
Pritchard KI, Shepherd LE, O'Malley FP, Andrulis IL, Tu D, Bramwell VH, et al. National cancer institute of Canada clinical trials group. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med. 2006;354:2103-11.
-
(2006)
N Engl J Med
, vol.354
, pp. 2103-2111
-
-
Pritchard, K.I.1
Shepherd, L.E.2
O'Malley, F.P.3
Andrulis, I.L.4
Tu, D.5
Bramwell, V.H.6
-
13
-
-
39149126730
-
HER-2 and topoisomerase II as predictors of response to chemotherapy
-
Pritchard KI, Messersmith H, Elavathil L, Trudeau M, O'Malley F, Dhesy-Thind B. HER-2 and topoisomerase II as predictors of response to chemotherapy. J Clin Oncol. 2008;26:736-44.
-
(2008)
J Clin Oncol
, vol.26
, pp. 736-744
-
-
Pritchard, K.I.1
Messersmith, H.2
Elavathil, L.3
Trudeau, M.4
O'Malley, F.5
Dhesy-Thind, B.6
-
14
-
-
0033870292
-
Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Järvinen TA, Tanner M, Rantanen V, Bärlund M, Borg A, Grénman S, et al. Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol. 2000;156:839-47.
-
(2000)
Am J Pathol
, vol.156
, pp. 839-847
-
-
Järvinen, T.A.1
Tanner, M.2
Rantanen, V.3
Bärlund, M.4
Borg, A.5
Grénman, S.6
-
15
-
-
16644362006
-
Correlation between topoisomerase-II alpha gene amplification and protein expression in HER-2 amplified breast cancer
-
Durbecq V, Desmed C, Paesmans M, Cardoso F, Di Leo A, Mano M, et al. Correlation between topoisomerase-II alpha gene amplification and protein expression in HER-2 amplified breast cancer. Int J Oncol. 2004;25:1473-9.
-
(2004)
Int J Oncol
, vol.25
, pp. 1473-1479
-
-
Durbecq, V.1
Desmed, C.2
Paesmans, M.3
Cardoso, F.4
Di Leo, A.5
Mano, M.6
-
16
-
-
3843120055
-
Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer
-
Cardoso F, Durbecq V, Larsimont D, Paesmans M, Leroy JY, Rouas G, et al. Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer. Int J Oncol. 2004;24:201-9.
-
(2004)
Int J Oncol
, vol.24
, pp. 201-209
-
-
Cardoso, F.1
Durbecq, V.2
Larsimont, D.3
Paesmans, M.4
Leroy, J.Y.5
Rouas, G.6
-
17
-
-
0036091354
-
HER-2 amplification and topoisomerase II alpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracyclinebased therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
-
Di Leo A, Gancberg D, Larsimont D, Tanner M, Jarvinen T, Rouas G, et al. HER-2 amplification and topoisomerase II alpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracyclinebased therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin Cancer Res. 2002;8:1107-16.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
Tanner, M.4
Jarvinen, T.5
Rouas, G.6
-
18
-
-
0036554731
-
Amplification and overexpression of topoisomerase II alpha predict response to anthracycline-based therapy in locally advanced breast cancer
-
Coon JS, Marcus E, Gupta-Burt S, Seelig S, Jacobson K, Chen S, et al. Amplification and overexpression of topoisomerase II alpha predict response to anthracycline-based therapy in locally advanced breast cancer. Clin Cancer Res. 2002;8:1061-7.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1061-1067
-
-
Coon, J.S.1
Marcus, E.2
Gupta-Burt, S.3
Seelig, S.4
Jacobson, K.5
Chen, S.6
-
19
-
-
33746746400
-
TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer
-
Villman K, Sjöström J, Heikkilä R, Hultborn R, Malmström P, Bengtsson NO, et al. TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer. Acta Oncol. 2006;45:590-6.
-
(2006)
Acta Oncol
, vol.45
, pp. 590-596
-
-
Villman, K.1
Sjöström, J.2
Heikkilä, R.3
Hultborn, R.4
Malmström, P.5
Bengtsson, N.O.6
-
20
-
-
53149089444
-
Topoisomerase II alpha gene status and prediction of pathological complete remission after anthracycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neupositive breast cancer
-
Orlando L, Del Curto B, Gandini S, Ghisini R, Pietri E, Torrisi R, et al. Topoisomerase II alpha gene status and prediction of pathological complete remission after anthracycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neupositive breast cancer. Breast. 2008;17:506-11.
-
(2008)
Breast
, vol.17
, pp. 506-511
-
-
Orlando, L.1
Del Curto, B.2
Gandini, S.3
Ghisini, R.4
Pietri, E.5
Torrisi, R.6
-
21
-
-
33746218733
-
Association between immunohistochemical expression of topoisomerase II alpha, HER2 and hormone receptors and response to primary chemotherapy in breast cancer
-
Manna Edel F, Teixeira LC, Alvarenga M. Association between immunohistochemical expression of topoisomerase II alpha, HER2 and hormone receptors and response to primary chemotherapy in breast cancer. Tumori. 2006;92:222-9.
-
(2006)
Tumori
, vol.92
, pp. 222-229
-
-
Manna, E.F.1
Teixeira, L.C.2
Alvarenga, M.3
-
22
-
-
0043236239
-
DNA topoisomerase II alpha expression and the response to primary chemotherapy in breast cancer
-
MacGrogan G, Rudolph P, Mascarel Id I, Mauriac L, Durand M, Avril A, et al. DNA topoisomerase II alpha expression and the response to primary chemotherapy in breast cancer. Br J Cancer. 2003;89:666-71.
-
(2003)
Br J Cancer
, vol.89
, pp. 666-671
-
-
MacGrogan, G.1
Rudolph, P.2
Mascarel, I.I.3
Mauriac, L.4
Durand, M.5
Avril, A.6
-
23
-
-
4444249420
-
Serial topoisomerase II expression in primary breast cancer and response to neoadjuvant anthracycline-based chemotherapy
-
Martin-Richard M, Muñoz M, Albanell J, Colomo L, Bellet M, Rey MJ, et al. Serial topoisomerase II expression in primary breast cancer and response to neoadjuvant anthracycline-based chemotherapy. Oncology. 2004;66:388-94.
-
(2004)
Oncology
, vol.66
, pp. 388-394
-
-
Martin-Richard, M.1
Muñoz, M.2
Albanell, J.3
Colomo, L.4
Bellet, M.5
Rey, M.J.6
-
24
-
-
7444252789
-
Topoisomerase-IIα expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel
-
Durbecq V, Paesmans M, Cardoso F, Desmedt C, Di Leo A, Chan S, et al. Topoisomerase-II alpha expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel. Mol Cancer Ther. 2004;3:1207-14. (Pubitemid 39440165)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.10
, pp. 1207-1214
-
-
Durbecq, V.1
Paesmans, M.2
Cardoso, F.3
Desmedt, C.4
Di Leo, A.5
Chan, S.6
Friedrichs, K.7
Pinter, T.8
Van Belle, S.9
Murray, E.10
Bodrogi, I.11
Walpole, E.12
Lesperance, B.13
Korec, S.14
Crown, J.15
Simmonds, P.16
Perren J., T.J.17
Leroy, J.-Y.18
Rouas, G.19
Sotiriou, C.20
Piccart, M.21
Larsimont, D.22
more..
-
25
-
-
42649141185
-
Topoisomerase II alpha-positive and BRCA1-negative phenotype: Association with favorable response to epirubicin-based regimens for human breast cancers
-
Miyoshi Y, Kurosumi M, Kurebayashi J, Matsuura N, Takahashi M, Tokunaga E, et al. Topoisomerase II alpha-positive and BRCA1-negative phenotype: association with favorable response to epirubicin-based regimens for human breast cancers. Cancer Lett. 2008;264:44-53.
-
(2008)
Cancer Lett
, vol.264
, pp. 44-53
-
-
Miyoshi, Y.1
Kurosumi, M.2
Kurebayashi, J.3
Matsuura, N.4
Takahashi, M.5
Tokunaga, E.6
-
26
-
-
9144242764
-
Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracyclinebased chemotherapy
-
Petit T, Wilt M, Velten M, Millon R, Rodier JF, Borel C, et al. Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracyclinebased chemotherapy. Eur J Cancer. 2004;40:205-11.
-
(2004)
Eur J Cancer
, vol.40
, pp. 205-211
-
-
Petit, T.1
Wilt, M.2
Velten, M.3
Millon, R.4
Rodier, J.F.5
Borel, C.6
-
27
-
-
32944475493
-
Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish breast cancer cooperative group
-
Knoop AS, Knudsen H, Balslev E, Rasmussen BB, Overgaard J, Nielsen KV, et al. Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish breast cancer cooperative group. J Clin Oncol. 2005;23:7483-90.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7483-7490
-
-
Knoop, A.S.1
Knudsen, H.2
Balslev, E.3
Rasmussen, B.B.4
Overgaard, J.5
Nielsen, K.V.6
-
28
-
-
33744969590
-
Topoisomerase II alpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracyclinebased adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian breast group trial 9401
-
Scandinavian Breast Group Trial 9401
-
Scandinavian Breast Group Trial 9401, Tanner M, Isola J, Wiklund T, Erikstein B, Kellokumpu-Lehtinen P, et al. Topoisomerase II alpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracyclinebased adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian breast group trial 9401. J Clin Oncol. 2006;24:2428-36.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2428-2436
-
-
Tanner, M.1
Isola, J.2
Wiklund, T.3
Erikstein, B.4
Kellokumpu-Lehtinen, P.5
-
29
-
-
0032816621
-
Prognostic significance of Ki-67 and topoisomerase II alpha expression in infiltrating ductal carcinoma of the breast. A multivariate analysis of 863 cases
-
Rudolph P, MacGrogan G, Bonichon F, Frahm SO, de Mascarel I, Trojani M, et al. Prognostic significance of Ki-67 and topoisomerase II alpha expression in infiltrating ductal carcinoma of the breast. A multivariate analysis of 863 cases. Breast Cancer Res Treat. 1999;55:61-71.
-
(1999)
Breast Cancer Res Treat
, vol.55
, pp. 61-71
-
-
Rudolph, P.1
MacGrogan, G.2
Bonichon, F.3
Frahm, S.O.4
De Mascarel, I.5
Trojani, M.6
-
30
-
-
33847017056
-
BRCA1-linked breast cancer (BC) is highly more chemosensitive than its BRCA2-linked or sporadic counterparts
-
Paper presented at, 18-22 October 2002, Nice, France, Abstract 120
-
Delaloge S, Pautier P, Kloos I. BRCA1-linked breast cancer (BC) is highly more chemosensitive than its BRCA2-linked or sporadic counterparts. Paper presented at 27th congress of the European society for medical oncology, 18-22 October 2002, Nice, France. 2002; Abstract 120.
-
(2002)
27th Congress of the European Society for Medical Oncology
-
-
Delaloge, S.1
Pautier, P.2
Kloos, I.3
-
31
-
-
0037303255
-
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data
-
Goffin JR, Chappuis PO, Bégin LR, Wong N, Brunet JS, Hamel N, et al. Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma: 10-year follow up data. Cancer. 2003;97:527-36.
-
(2003)
Cancer
, vol.97
, pp. 527-536
-
-
Goffin, J.R.1
Chappuis, P.O.2
Bégin, L.R.3
Wong, N.4
Brunet, J.S.5
Hamel, N.6
-
32
-
-
0043130465
-
The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells
-
Fedier A, Steiner RA, Schwarz VA, Lenherr L, Haller U, Fink D. The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells. Int J Oncol. 2003;22:1169-73.
-
(2003)
Int J Oncol
, vol.22
, pp. 1169-1173
-
-
Fedier, A.1
Steiner, R.A.2
Schwarz, V.A.3
Lenherr, L.4
Haller, U.5
Fink, D.6
-
33
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
-
Liedtke C, Mazouni C, Hess KR, André F, Tordai A, Mejia JA, et al. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol. 2008;26:1275-81.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
André, F.4
Tordai, A.5
Mejia, J.A.6
-
34
-
-
23844549918
-
Breast cancer molecular subtypes respond differently to preoperative chemotherapy
-
Rouzier R, Perou CM, Symmans WF, Ibrahim N, Cristofanilli M, Anderson K, et al. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res. 2005;11:5678-85.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5678-5685
-
-
Rouzier, R.1
Perou, C.M.2
Symmans, W.F.3
Ibrahim, N.4
Cristofanilli, M.5
Anderson, K.6
-
35
-
-
34547836352
-
Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracyclines-based chemotherapy: A biomarker study from two randomized trials
-
Conforti R, Boulet T, Tomasic G, Taranchon E, Arriagada R, Spielmann M, et al. Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracyclines-based chemotherapy: a biomarker study from two randomized trials. Ann Oncol. 2007;18:1477-83.
-
(2007)
Ann Oncol
, vol.18
, pp. 1477-1483
-
-
Conforti, R.1
Boulet, T.2
Tomasic, G.3
Taranchon, E.4
Arriagada, R.5
Spielmann, M.6
-
36
-
-
34447298245
-
Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer
-
Arriola E, Rodriguez-Pinilla SM, Lambros MB, Jones RL, James M, Savage K, et al. Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer. Breast Cancer Res Treat. 2007;106:181-9.
-
(2007)
Breast Cancer Res Treat
, vol.106
, pp. 181-189
-
-
Arriola, E.1
Rodriguez-Pinilla, S.M.2
Lambros, M.B.3
Jones, R.L.4
James, M.5
Savage, K.6
|