Inhibition of transcription factor assembly and structural stability on mitoxantrone binding with DNA

Bioscience Reports

Volumn 30, Issue 5, 2010, Pages 331-340

  Khan, Shahper N ^a   Danishuddin, Mohd ^a   Khan, Asad U ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

DNA binding specificity; Mitoxantrone; Structural perturbation; Thermodynamics; Transcription inhibition

Indexed keywords

DNA; MITOXANTRONE; OCTAMER TRANSCRIPTION FACTOR; ANTINEOPLASTIC AGENT; CALF THYMUS DNA; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA CONFORMATION; DNA DRUG COMPLEX; DRUG DNA BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENTROPY; FLUORESCENCE ANALYSIS; GEL MOBILITY SHIFT ASSAY; INFRARED SPECTROSCOPY; INHIBITION KINETICS; MOLECULAR MODEL; MOLECULAR STABILITY; NONHUMAN; PROTEIN ASSEMBLY; STEADY STATE; TEMPERATURE DEPENDENCE; THERMODYNAMICS; THYMUS; TRANSCRIPTION TERMINATION; ANIMAL; CATTLE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM;

ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CELL LINE; CIRCULAR DICHROISM; DNA; HUMANS; MITOXANTRONE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS; TRANSCRIPTION FACTORS;

EID: 77954701438     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSR20090083     Document Type: Article

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