Bone marrow angiogenesis in multiple myeloma and its correlation with clinicopathological factors

Annals of Hematology

Volumn 89, Issue 8, 2010, Pages 789-794

  Rana, Chanchal ^a   Sharma, Seema ^a   Agrawal, Vinita ^a   Singh, Uttam ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Angiogenesis; Clinicopathological factors; Computerized image analysis; Microvessel density; Multiple myeloma

Indexed keywords

CD34 ANTIGEN;

ADULT; AGED; ARTICLE; BLOOD VESSEL PARAMETERS; BONE MARROW BIOPSY; BONE MARROW EXAMINATION; CANCER GRADING; CANCER GROWTH; CANCER MORPHOLOGY; CANCER SURVIVAL; CELL INFILTRATION; CELL STRUCTURE; CLINICAL FEATURE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; MICROVASCULATURE; MICROVESSEL DENSITY; MINIMAL RESIDUAL DISEASE; MULTIPLE MYELOMA; PLASMA CELL; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; TOTAL VASCULAR AREA; TREATMENT RESPONSE; TUMOR VASCULARIZATION; TUMOR VOLUME; BIOPSY; BONE MARROW; MIDDLE AGED; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RETROSPECTIVE STUDY;

ADULT; AGED; BIOPSY; BONE MARROW; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE MYELOMA; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 77954683011     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-010-0919-z     Document Type: Article

References (14)

1. Carmeliet P (2003) Angiogenes in health and disease. Nat Med 9:653-660
2. Moehler TM, Neben K, Ho AD, Goldschmidt H (2001) Angiogenesis in hematologic malignancies. Ann Hematol 80:695-705
3. Dispenzieri A, Lacy MQ, Greipp PR (2001) Multiple myeloma in Winterobe's clinical hematology, vol 2, 11th edn. Lipincott, Williams and Wilkins, Philadelphia, pp 2583-2636
4. Sezer O, Niemöller K, Eucker J, Jakob C, Kaufmann O, Zavrski I, Dietel M, Possinger M (2000) Bone marrow microvessel density is a prognostic factor for survival in patients with multiple myeloma. Ann Haematol 79:574-577
5. Fox SB, Leek RD, Weekes MP, Whitehouse RM, Gatter KC, Harris AL (1995) Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density. Chalkley count, and computer image analysis. J Pathol 177:275-283
6. Rajkumar SV, Leong T, Roche PC (2000) Prognostic value of bone marrow angiogenesis in multiple myeloma. Clin Cancer Res 6:3111-3116
7. Bhatti SS, Kumar L, Dinda AK, Dawar R (2006) Prognostic value of bone marrow angiogenesis in multiple myeloma: Use of light microscopy as well as computerized image analyzer in the assessment of microvessel density and total vascular area in multiple myeloma and its correlation with various clinical, histological, and laboratory parameters. Am J Hematol 81:649-656
8. Bartl R, Frisch B, Fateh Moghadam A et al (1987) Histologic classification and staging of multiple myeloma: A retrospective and prospective study of 674 cases. Am J Clin Pathol 87:342-355
9. Vacca A, Ribatti D, Roccaro AM, Frigeri A, Dammacco F (2001) Bone marrow angiogenesis in patients with active multiple myeloma. Semin Oncol 28:543-550
10. Rajkumar SV, Witzig TE, Gertz MA, Griepp PR (1998) Computerized image analysis in the assessment of bone marrow angiogenesis in multiple myeloma. Blood 92suppI:100a
11. Vacca A, Ribatti D, Roncali L, Ranieri G, Serio G, Silvestris F, Dammacco F (1994) Bone marrow angiogenesis and progression in multiple myeloma. Br J Haematol 87:503-508
12. Munshi N, Wilson CS, Penn J, Epstein J, Singhal S, Hough A, Sanderson R, Desikan R, Seigel D, Mehta J, Barlogie B (1998) Angiogenesis in newly diagnosed multiple myeloma: Poor prognosis with increased microvessel density in bone marrow biopsies (abstract). Blood 92(Suppl 1):98a
13. Singhal S, Mehta J, Desikan R, Ayers D, Robertson P, Eddlemen P, Munshi N, Anaissie E, Wilson C, Dhodapkar M, Zeldis J, Barlogie B (1999) N Eng J Med 341:1565-1571
14. Carter A, Hocherman I, Linn S, Cohen Y, Tatarsky I (1987) Prognostic significance of plasma cell morphology in multiple myeloma. Cancer 60:1060-1065