Apoptosis of rat's ovarian follicle cells induced by triptolide in vivo

African Journal of Pharmacy and Pharmacology

Volumn 4, Issue 6, 2010, Pages 422-430

  Xu, Cheng kang ^a   Zhao, Yun he ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Ovarian follicle; Rat; Triptolide

Indexed keywords

DIMETHYL SULFOXIDE; PLACEBO; TRIPTOLIDE; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG MEGADOSE; ESTRUS CYCLE; FEMALE; GROWTH RATE; HISTOLOGY; IN VIVO STUDY; INHIBITION KINETICS; LOW DRUG DOSE; NONHUMAN; OVARY FOLLICLE; OVARY FOLLICLE CELL; RAT; VAGINA SMEAR;

EID: 77954666552     PISSN: None     EISSN: 19960816     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Corson TW, Crews CM (2007). Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell. 130: 769-774.
2. Fu P, Mao CS, Gong Y (1999). Study on sex hormone levels in Tripterygium wilfordii induced amenorrhea: analysis of 9 cases. J Clin Dermatol. 28: 163-164.
3. Gaytán F, Morales C, Bellido C (1996), Aguilar E and Sa'nchez-Criado JE: Proliferative activity in the different ovarian compartments in cycling rats estimated by the 5-bromodeoxyuridine technique. Biol Reprod. 54: 1356-1365.
4. Kupchan SM, Court WA, Dailey RG (1972). Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Triperygium. wilfordii. J Am Chem Soc. 94: 7194-7195.
5. Kupehan SM (1974). Selective alkylation: A Biomimetic reation of the antilenkemic triptolide. Science. 185: 791-793.
6. Myers M, Britt KL, Wreford NG, Ebling FJP, Kerr JB (2004). Methods for quantifying follicle numbers within the mouse ovary. Reprod. 127: 569-580.
7. Pan JQ, Zeng Y, Yang YJ (2006). Expression of Vascular Endothelial Growth Factor Inhibited by Triptolide in Murine Macrophages. Reprod & Contrac. 26: 142-145
8. Wang Y, Sun YB, Chen QQ (1993). Effect of Triptolide on Reproductive Endocrinology and Dihydrotestosterone Receptors in Rats. J Chin Pharmac Sci. 2: 53-58.
9. Xu CK, Zhao YH (2008). Influence of Tripterygium Hypoglaucum Hutch on Function of Ovary in Reproductive Age Women. J Sun Yat-Sen Univ (Med Sci). 29: 202-205.
10. Yang J, Dong JC, Han B (2006). Effect of glycosides of tripterygium wilfordii Hook.f. on procreation and endocrine of womenfolk. Chin J Pharmac and Toxic. 20: 437-440.