메뉴 건너뛰기




Volumn 23, Issue 4, 2010, Pages 323-330

Primary aldosteronism and its impact on the generation of arterial hypertension, endothelial injury and oxidative stress

Author keywords

Arterial hypertension; Endothelial injury; Oxidative stress; Primary aldosteronism

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 2; ALDOSTERONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN II; CORTICOTROPIN; CYTOCHROME P450C17; DEXAMETHASONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUDROCORTISONE; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; HYDROGEN PEROXIDE; I KAPPA B; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN; MINERALOCORTICOID RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PLASMINOGEN ACTIVATOR INHIBITOR; REACTIVE OXYGEN METABOLITE; SPIRONOLACTONE; STEROID 11BETA MONOOXYGENASE; STEROID 17ALPHA MONOOXYGENASE; SUPEROXIDE; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77954662981     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/jpem.2010.052     Document Type: Review
Times cited : (11)

References (65)
  • 2
    • 15344350095 scopus 로고    scopus 로고
    • A diagnostic approach for the child with hypertension
    • Marcun NV, Gregorio A. A diagnostic approach for the child with hypertension. Pediatr Nephrol 2005; 20: 499-506.
    • (2005) Pediatr Nephrol , vol.20 , pp. 499-506
    • Marcun, N.V.1    Gregorio, A.2
  • 3
    • 1442323883 scopus 로고    scopus 로고
    • Overweight, ethnicity and the prevalence of hypertension in school-aged children
    • Sorof JM, Lai D, Turner J, Poffenbarger T, Portman RJ. Overweight, ethnicity and the prevalence of hypertension in school-aged children. Pediatrics 2004; 113: 475-82
    • (2004) Pediatrics , vol.113 , pp. 475-482
    • Sorof, J.M.1    Lai, D.2    Turner, J.3    Poffenbarger, T.4    Portman, R.J.5
  • 4
    • 34548092397 scopus 로고    scopus 로고
    • Underdiagnosis of Hypertension in Chidren and Adolescents
    • Hansen M, Gunn P, Kaelber D. Underdiagnosis of Hypertension in Chidren and Adolescents. JAMA 2007; 298: 874-9.
    • (2007) JAMA , vol.298 , pp. 874-879
    • Hansen, M.1    Gunn, P.2    Kaelber, D.3
  • 8
    • 25844486955 scopus 로고
    • Normokalemic primary aldosteronism. A detectable cause of curable "essential" hypertension
    • Conn JW, Cohen EL, Rovner DR, Nesbit RM. Normokalemic primary aldosteronism. A detectable cause of curable "essential" hypertension. JAMA 1965; 193:200-206
    • (1965) JAMA , vol.193 , pp. 200-206
    • Conn, J.W.1    Cohen, E.L.2    Rovner, D.R.3    Nesbit, R.M.4
  • 13
    • 0036203230 scopus 로고    scopus 로고
    • Primary aldosteronism
    • Fardella CE, Mosso L. Primary aldosteronism. Clin Lab. 2002; 48:181-90.
    • (2002) Clin Lab , vol.48 , pp. 181-190
    • Fardella, C.E.1    Mosso, L.2
  • 14
    • 0031993385 scopus 로고    scopus 로고
    • Measurement of low levels of plasma rennin activity. A methodological improvement
    • Montera J, Soto J, Fardella C, Foradori A, Valdés G. Measurement of low levels of plasma rennin activity. A methodological improvement Rev Med Chil. 1998; 126:151-4.
    • (1998) Rev Med Chil , vol.126 , pp. 151-154
    • Montera, J.1    Soto, J.2    Fardella, C.3    Foradori, A.4    Valdés, G.5
  • 15
    • 0033127440 scopus 로고    scopus 로고
    • Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements
    • May
    • Fardella CE, Montera J, Mosso L. [Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements].Rev Med Chil. 1999 May; 127:604-10.
    • (1999) Rev Med Chil , vol.127 , pp. 604-610
    • Fardella, C.E.1    Montera, J.2    Mosso, L.3
  • 16
    • 0036793584 scopus 로고    scopus 로고
    • High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives
    • Rossi E, Regolisti G, Negro A, Sani C, Davoli S, Perazzoli F. High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. Am J Hypertens 2002; 15: 896-902.
    • (2002) Am J Hypertens , vol.15 , pp. 896-902
    • Rossi, E.1    Regolisti, G.2    Negro, A.3    Sani, C.4    Davoli, S.5    Perazzoli, F.6
  • 17
    • 0036841187 scopus 로고    scopus 로고
    • Screening for primary aldosteronism: Implications of an increased plasma aldosterone/renin ratio
    • Schwartz Gl, Chapman AB, Boerwinkle E, Kisabeth RM, Turner ST. Screening for primary aldosteronism: implications of an increased plasma aldosterone/ renin ratio. Clin Chem 2002; 48: 1919-23. (Pubitemid 35222749)
    • (2002) Clinical Chemistry , vol.48 , Issue.11 , pp. 1919-1923
    • Schwartz, G.L.1    Chapman, A.B.2    Boerwinkle, E.3    Kisabeth, R.M.4    Turner, S.T.5
  • 18
    • 0034069789 scopus 로고    scopus 로고
    • The aldosterone/renin ratio as a screening test for primary aldosteronaism
    • Rayner Bl, Opie LH, Davidson JS. The aldosterone/renin ratio as a screening test for primary aldosteronaism. South African Medical Journal 2000; 90: 394-400.
    • (2000) South African Medical Journal , vol.90 , pp. 394-400
    • Rayner, Bl.1    Opie, L.H.2    Davidson, J.S.3
  • 20
    • 0028818948 scopus 로고
    • Primary aldosteronism
    • Gordon RD. Primary aldosteronism. J Endocrinol Invest 1995; 18: 495-511.
    • (1995) J Endocrinol Invest , vol.18 , pp. 495-511
    • Gordon, R.D.1
  • 21
    • 0026701168 scopus 로고
    • Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2
    • Pascoe L, Curnow KM, Slutsker L, Connell JM, Speiser PW, New MI et al. Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc Natl Acad Sci USA 1992; 89: 8327-31.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8327-8331
    • Pascoe, L.1    Curnow, K.M.2    Slutsker, L.3    Connell, J.M.4    Speiser, P.W.5    New, M.I.6
  • 22
    • 0026580019 scopus 로고
    • A chimaeric 11 beta-hydroxylase/ aldosterone synthase gene causes glucocorticoidremediable aldosteronism and human hypertension
    • Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S et al. A chimaeric 11 beta-hydroxylase/ aldosterone synthase gene causes glucocorticoidremediable aldosteronism and human hypertension. Nature 1992; 355: 262-5.
    • (1992) Nature , vol.355 , pp. 262-265
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3    Rich, G.M.4    Cook, S.5    Ulick, S.6
  • 23
  • 24
    • 0028890480 scopus 로고
    • A new genetic test for familial hyperaldosteronism type I aids in the detection of curable hypertension
    • Jonsson JR, Klemm SA, Tunny TJ, Stowasser M, Gordon RD. A new genetic test for familial hyperaldosteronism type I aids in the detection of curable hypertension. Biochem Biophys Res Commun 1995; 207: 565-71.
    • (1995) Biochem Biophys Res Commun , vol.207 , pp. 565-571
    • Jonsson, J.R.1    Klemm, S.A.2    Tunny, T.J.3    Stowasser, M.4    Gordon, R.D.5
  • 25
    • 0034896157 scopus 로고    scopus 로고
    • Aldosterone as a determinant of cardiovascular and renal dysfunction
    • Epstein M. Aldosterone as a determinant of cardiovascular and renal dysfunction. J R Soc Med. 2001 94(8):378-83. (Pubitemid 32738676)
    • (2001) Journal of the Royal Society of Medicine , vol.94 , Issue.8 , pp. 378-383
    • Epstein, M.1
  • 26
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Pérez A et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-17.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Pérez, A.6
  • 27
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B, Remme W, Zannad F, Neaton J, Martínez F, Roniker B et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 2003; 348:1309-21.
    • (2003) N Engl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3    Neaton, J.4    Martínez, F.5    Roniker, B.6
  • 28
    • 17144421237 scopus 로고    scopus 로고
    • Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism
    • Milliez P, Girerd X, Plouin PF, Blacher J, Safar Me, Mourad Jj. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol 2005; 45: 1243-8.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1243-1248
    • Milliez, P.1    Girerd, X.2    Plouin, P.F.3    Blacher, J.4    Safar, Me.5    Mourad, Jj.6
  • 30
    • 7944222897 scopus 로고    scopus 로고
    • The role of the renin-angiotensin aldosterone system in diabetes and its vascular complications
    • quiz A2-4.Review
    • Cooper ME. The role of the renin-angiotensin aldosterone system in diabetes and its vascular complications. Am J Hypertens 2004; 17(11pt2): 16S-20S; quiz A2-4.Review
    • (2004) Am J Hypertens , vol.17 , Issue.11 PART2
    • Cooper, M.E.1
  • 31
    • 0035022922 scopus 로고    scopus 로고
    • Aldosterone and the hypertensive kidney: Its emerging role as a mediator of progressive renal dysfunction: A paradigm shift
    • Epstein M. Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift. J Hypertension 2001; 19: 829-42.
    • (2001) J Hypertension , vol.19 , pp. 829-842
    • Epstein, M.1
  • 33
    • 66549112420 scopus 로고    scopus 로고
    • Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: Insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study
    • Iraqi W, Rossignol P, Angioi M, Fay R, Nuée J, Ketelslegers JM, Vincent J, Pitt B, Zannad F. Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study. Circulation. 2009; 119(18):2471-9.
    • (2009) Circulation , vol.119 , Issue.18 , pp. 2471-2479
    • Iraqi, W.1    Rossignol, P.2    Angioi, M.3    Fay, R.4    Nuée, J.5    Ketelslegers, J.M.6    Vincent, J.7    Pitt, B.8    Zannad, F.9
  • 35
    • 0041318968 scopus 로고    scopus 로고
    • Nongenomic vascular action of aldosterone in the glomerular microcirculation
    • Arima S, Kohagura K, Xu Hl, Sugawara A, Abe T, Satoh F et al. Nongenomic vascular action of aldosterone in the glomerular microcirculation. J Am Soc Nephrol 2003; 14: 2255-63.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2255-2263
    • Arima, S.1    Kohagura, K.2    Hl, X.3    Sugawara, A.4    Abe, T.5    Satoh, F.6
  • 37
    • 38549092093 scopus 로고    scopus 로고
    • Aldosterone and vascular inflammation
    • Brown N. Aldosterone and vascular inflammation Hypertension 2008; 51:161-167
    • (2008) Hypertension , vol.51 , pp. 161-167
    • Brown, N.1
  • 38
    • 1342324062 scopus 로고    scopus 로고
    • Review of aldosterone - and angiotensin II induced target organ damage and prevention
    • Struthers A, MacDonald T. Review of aldosterone - and angiotensin II induced target organ damage and prevention Cardiovascular research 2004; 61: 663-670
    • (2004) Cardiovascular Research , vol.61 , pp. 663-670
    • Struthers, A.1    MacDonald, T.2
  • 39
    • 0242525727 scopus 로고    scopus 로고
    • Aldosterone regulates vascular reactivity: Short-term effects mediated by phosphatidylinositol 3-kinase-dependent nitric oxide synthase activation
    • Liu, S. L., Schmuck, S., Chorazcyzewski, J. Z., Gros, R., Feldman, R. D. Aldosterone regulates vascular reactivity: short-term effects mediated by phosphatidylinositol 3-kinase-dependent nitric oxide synthase activation. Circulation 2003; 108: 2400-2240.
    • (2003) Circulation , vol.108 , pp. 2400-12240
    • Liu, S.L.1    Schmuck, S.2    Chorazcyzewski, J.Z.3    Gros, R.4    Feldman, R.D.5
  • 40
    • 65549123191 scopus 로고    scopus 로고
    • Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells
    • Maron BA, Zhang YY, Handy DE, Beuve A, Tang SS, Loscalzo J, Leopold JA. Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells. J Biol Chem. 2009; 284: 7665-7672.
    • (2009) J Biol Chem , vol.284 , pp. 7665-7672
    • Maron, B.A.1    Zhang, Y.Y.2    Handy, D.E.3    Beuve, A.4    Tang, S.S.5    Loscalzo, J.6    Leopold, J.A.7
  • 42
    • 56049085140 scopus 로고    scopus 로고
    • Association of tumor necrosis factor-alpha with early target organ damage in newly diagnosed patients with essential hypertension
    • Navarro-González JF, Mora C, Muros M, Jarque A, Herrera H, García J. Association of tumor necrosis factor-alpha with early target organ damage in newly diagnosed patients with essential hypertension. J Hypertens. 2008; 26: 2168-75.
    • (2008) J Hypertens , vol.26 , pp. 2168-2175
    • Navarro-González, J.F.1    Mora, C.2    Muros, M.3    Jarque, A.4    Herrera, H.5    García, J.6
  • 44
    • 64949130712 scopus 로고    scopus 로고
    • Elevated serum interleukin 6 levels in normotensive individuals with familial hyperaldosteronism type 1
    • Staermose S, Marwick TH, Gordon RD, Cowley D, Dowling A, Stowasser M. Elevated serum interleukin 6 levels in normotensive individuals with familial hyperaldosteronism type 1. Hypertension. 2009; 53: e31-2.
    • (2009) Hypertension , vol.53
    • Staermose, S.1    Marwick, T.H.2    Gordon, R.D.3    Cowley, D.4    Dowling, A.5    Stowasser, M.6
  • 47
    • 0028167769 scopus 로고
    • Disorders of steroid 11 beta-hydroxylase isozymes
    • Aug
    • White PC, Curnow KM, Pascoe L. Disorders of steroid 11 beta-hydroxylase isozymes. Endocr Rev. 1994 Aug; 15(4):421-38.
    • (1994) Endocr Rev , vol.15 , Issue.4 , pp. 421-438
    • White, P.C.1    Curnow, K.M.2    Pascoe, L.3
  • 48
    • 0025847381 scopus 로고
    • A mutation in CYP11B1 (Arg-448-His) associated with steroid 11 beta-hydroxylase deficiency in Jews of Moroccan origin
    • May
    • White PC, Dupont J, New MI, Leiberman E, Hochberg Z, Rösler A. A mutation in CYP11B1 (Arg-448-His) associated with steroid 11 beta-hydroxylase deficiency in Jews of Moroccan origin. J Clin Invest. 1991 May; 87(5):1664-7.
    • (1991) J Clin Invest , vol.87 , Issue.5 , pp. 1664-1667
    • White, P.C.1    Dupont, J.2    New, M.I.3    Leiberman, E.4    Hochberg, Z.5    Rösler, A.6
  • 49
    • 0029799269 scopus 로고    scopus 로고
    • Molecular biology of mineralocorticoid metabolism
    • Fardella CE, Miller WL. Molecular biology of mineralocorticoid metabolism. Annu Rev Nutr. 1996; 16:443-70.
    • (1996) Annu Rev Nutr , vol.16 , pp. 443-470
    • Fardella, C.E.1    Miller, W.L.2
  • 50
    • 0026081588 scopus 로고
    • 17 alpha-hydroxylase/17,20-lyase deficiency: From clinical investigation to molecular definition
    • Yanase T, Simpson ER, Waterman MR. 17 alpha-hydroxylase/17,20-lyase deficiency: from clinical investigation to molecular definition. Endocr Rev. 1991; 12(1):91-108.
    • (1991) Endocr Rev , vol.12 , Issue.1 , pp. 91-108
    • Yanase, T.1    Simpson, E.R.2    Waterman, M.R.3
  • 51
    • 0027228216 scopus 로고
    • Deletion of amino acids Asp487-Ser488-Phe489 in human cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency
    • Fardella CE, Zhang LH, Mahachoklertwattana P, Lin D, Miller WL. Deletion of amino acids Asp487-Ser488-Phe489 in human cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency. J Clin Endocrinol Metab. 1993; 77(2): 489-93.
    • (1993) J Clin Endocrinol Metab , vol.77 , Issue.2 , pp. 489-493
    • Fardella, C.E.1    Zhang, L.H.2    Mahachoklertwattana, P.3    Lin, D.4    Miller, W.L.5
  • 52
    • 0028318144 scopus 로고
    • Point mutation of Arg440 to His in cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency
    • Fardella CE, Hum DW, Homoki J, Miller WL
    • Fardella CE, Hum DW, Homoki J, Miller WL. Point mutation of Arg440 to His in cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency. Fardella CE, Hum DW, Homoki J, Miller WL. J Clin Endocrinol Metab. 1994; 79(1): 160-4.
    • (1994) J Clin Endocrinol Metab , vol.79 , Issue.1 , pp. 160-164
    • Fardella, C.E.1    Hum, D.W.2    Homoki, J.3    Miller, W.L.4
  • 53
    • 0029847663 scopus 로고    scopus 로고
    • Inherited forms of mineralocorticoid hypertension
    • White PC. Inherited forms of mineralocorticoid hypertension.Hypertension 1996; 28(6):927-36.
    • (1996) Hypertension , vol.28 , Issue.6 , pp. 927-936
    • White, P.C.1
  • 54
    • 0023760499 scopus 로고
    • Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle
    • Stewart PM, Corrie JE, Shackleton CH, Edwards CR. Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle.J Clin Invest. 1988; 82(1): 340-9.
    • (1988) J Clin Invest , vol.82 , Issue.1 , pp. 340-349
    • Stewart, P.M.1    Corrie, J.E.2    Shackleton, C.H.3    Edwards, C.R.4
  • 56
    • 0029160972 scopus 로고
    • Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase
    • Mune T, Rogerson FM, Nikkilä H, Agarwal AK, White PC. Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase. Nat Genet. 1995; 10(4):394-9.
    • (1995) Nat Genet , vol.10 , Issue.4 , pp. 394-399
    • Mune, T.1    Rogerson, F.M.2    Nikkilä, H.3    Agarwal, A.K.4    White, P.C.5
  • 57
    • 0023221667 scopus 로고
    • Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor
    • Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE, Evans RM. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science. 1987; 237(4812): 268-75. (Pubitemid 17095145)
    • (1987) Science , vol.237 , Issue.4812 , pp. 268-275
    • Arriza, J.L.1    Weinberger, C.2    Cerelli, G.3
  • 60
    • 0033577487 scopus 로고    scopus 로고
    • Mineralocorticoid hypertension
    • Stewart PM. Mineralocorticoid hypertension. Lancet 1999; 353(9161): 1341-7.
    • (1999) Lancet , vol.353 , Issue.9161 , pp. 1341-1347
    • Stewart, P.M.1
  • 61
    • 0030049329 scopus 로고    scopus 로고
    • Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11 beta-hydroxysteroid dehydrogenase type 2 gene
    • Stewart PM, Krozowski ZS, Gupta A, Milford DV, Howie AJ, Sheppard MC, Whorwood CB. Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11 beta-hydroxysteroid dehydrogenase type 2 gene. Lancet. 1996; 347(8994): 88-91.
    • (1996) Lancet , vol.347 , Issue.8994 , pp. 88-91
    • Stewart, P.M.1    Krozowski, Z.S.2    Gupta, A.3    Milford, D.V.4    Howie, A.J.5    Sheppard, M.C.6    Whorwood, C.B.7
  • 62
    • 34347232679 scopus 로고    scopus 로고
    • Novel causes of generalized glucocorticoid resistance
    • Charmandari E, Kino T. Novel causes of generalized glucocorticoid resistance. Horm Metab Res. 2007; 39(6):445-50.
    • (2007) Horm Metab Res , vol.39 , Issue.6 , pp. 445-450
    • Charmandari, E.1    Kino, T.2
  • 65
    • 0037320545 scopus 로고    scopus 로고
    • The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related
    • Rafestin-Oblin ME, Souque A, Bocchi B, Pinon G, Fagart J, Vandewalle A. The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related. Endocrinology. 2003; 144(2):528-33.
    • (2003) Endocrinology , vol.144 , Issue.2 , pp. 528-533
    • Rafestin-Oblin, M.E.1    Souque, A.2    Bocchi, B.3    Pinon, G.4    Fagart, J.5    Vandewalle, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.