Enhanced production of valerenic acids and valepotriates by in vitro cultures of Valeriana officinalis L

International Journal of Plant Production

Volumn 4, Issue 3, 2010, Pages 209-222

  Ekhteraei Tousi, S ^a   Radjabian, T ^b   Ebrahimzadeh, H ^a   Niknam, V ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

^b SHAHED UNIVERSITY   (Iran)

Author keywords

Plant tissue culture; Valepotriates; Valerenic acids; Valeriana officinalis l.

Indexed keywords

VALERIANA; VALERIANA OFFICINALIS;

EID: 77954661626     PISSN: 17356814     EISSN: 17358043     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Banerjee, S., Rahman, L., Uniyal, G.C., Ahuja, P.S., 1998. Enhanced production of valepotriates by Agrobacterium rhizogeneses induced hairy root cultures of Valeriana wallichii DC. Plant Sci. 131: 203-208.
2. Becker, H., Chavadej, S., 1988. Valepotriates: Production by plant cell cultures. In: Bajaj, Y.P.S. (Ed.), Biotechnology in Agriculture and Forestry, Vol. 4. Medicinal and Aromatic Plants. Springer-Verlag, Berlin Heidelberg New York, Pp: 294-309.
3. Becker, H., Schrall, R., Hartmann, W., 1977. Calluskulturen von Baldrian-Arten, 1. Mitt. Aniage einer Calluskutur von Valeriana wallichii DC. und erste analystische Untersuchungen. Arch Pharm. 310: 481-484.
4. Bos, R., Woerdenbag, H.J., Hendriks, H., Zwaving, J.H., De Smet, P.A.G.M., Tittlel, G., Wikstrom, H.V., Scheffer, J.J.C., 1996. Analytical aspects of phytotherapeutic valerian preparations. Phytochem Anal. 7: 143-151.
5. Bos, R., 1997. Analytical and phytochemical studies on valerian and valerian based preparations. Groningen University, Netherlands.
6. Bos, R., Woerdenbag, H.J., Pras, N., 2002. Determination of valepotriates. J. Chromatogr. A. 967: 131-146.
7. Caetano, C.L., Charlwood, B.V., Gahan, P.B., 1999. The localization and accumulation of valepotriates in hairy roots of Valerianella discoidea (L.) Loisel. Phytochem Anal. 10: 181-186.
8. Castillo, P., Zamilpa, A., Marquez, J., Hernandez, G., Lara, M., Alvarez, L., 2002. Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp. Procera. J Nat Prod. 65: 573-575.
9. De Carvalho, C.M., Maurmann, N., Luz, D.I., Fett-Neto, A.G., Rech, S.B., 2004. Control of development and valepotriate production by auxins in micropropagated Valeriana glechomifolia. Plant Cell Rep. 23: 251-255.
10. Dietz, B.M., Mahady, G.B., Pauli, G.F., Farnsworth, N.R., 2005. Valerian extract and valerenic acids are partial agonists of the 5-HT5a receptor in vitro. Mol Brain Res. 138: 191-197.
11. Ebrahimzadeh, H., Radjabian, T., Ekhteraei Tousi, S., Bashiri Sadr, Z., Niknam, V., Zarrei, M., 2008. Quantification of valerenic acid and its derivatives in some species of Valeriana L. and Centranthus longiflorus Stev. Asian J. Plant Sci. 7: 195-200.
12. Ebrahimzadeh, H., Radjabian, T., Ekhteraei Tousi, S., Niknam, V., Mozaffarian, V., 2008. Evaluation of some Iranian wild species from Valerianaceae as commercial sources of valepotriates. J. Biol. Sci. 8: 549-555
13. Granicher, F., Christen P.H., Kapetanidis, I., 1992. High-yield production of valepotriates by hairy root cultures of Valeriana officinalis L. var. sambucifolia Mikan. Plant Cell Rep. 11: 339-342.
14. Granicher, F., Christen, P.H., Kapetanidis, I., 1995. Production of valepotriates by hairy root cultures of Centranthus ruber DC. Plant Cell Rep. 14: 294-298.
15. Li, M.Y., Ahn, J.C., Kim, K.S., Kim, O.T., Park, Y.J., Hwang, B., 2006. Comparison of valerenic acids and valepotriates production according to the culture conditions for cultured roots of Valeriana fauriei var. dasycarpa. Korean J. Medicinal Crop Sci. 14: 101-106.
16. Maurmann, N., De Carvalho, C.M.B., Silva, A.I.L., Fett-Neto, A.G., Von Poser, G.L., Rech, S.B., 2006. Valepotriates accumulation in callus, suspended cells and untransformed root cultures of Valeriana glechomifolia. In Vitro Cell Dev Biol Plant. 42: 50-53.
17. Murashige, T., Skoog, F., 1962. A revised medium for rapid growth and bioassays with to bacco tissue cultures. Physiol Plant. 15: 473-479.
18. Pras, N., 2000. Cell Technology. In: Spier, R. (Ed.) The Encyclopedia. Wiley and Sons, New York, 1015 p.
19. Russowski, D., Maurmann, N., Rech, S.B., Fett-Neto, A.G., 2006. Role of light and medium composition on growth and valepotriate contents in Valeriana glechomifolia whole plant liquid cultures. Plant Cell Tiss Org. 86: 211-218.
20. Salles, L.A., Silva, A.L., Fett-Neto, A.G., Poser, G.L., Rech, S.B., 2002. Valeriana glechomifolia: in vitro propagation and production of valepotriates. Plant Sci. 163: 165-168.
21. Silva, A.L., Rech, S.B., Poser, G.L., 2002. Quantitative determination of valepotriates from Valeriana native to south Brazil. Planta Med. 68: 570-572.
22. Upton, H.R., Petrone, C., Swisher, D., Goldberg, A., Mc Guffin, M., Pizzorno, N.D.J., 1999. Valerian root, Valeriana officinalis, Analytical, Quality Control, and Therapeutic Monograph. American Herbal Pharmacopoeia and Therapeutic Compendium. Retrieved 14 Oct 2006 in http://www.herbal-ahp.org.html.
23. Violon, C., Van Cauwenbergh, N., Vercruysse, A., 1983. Valepotriate content in different in vitro cultures of Valerianaceae and characterization of Valeriana officinalis L. callus during a growth period. Pharm. Weekblad. 5: 205-209.