About oral absorption and human pharmacokinetics of chondroitin sulfate

Osteoarthritis and Cartilage

Volumn 18, Issue 8, 2010, Pages 1104-1105

  Volpi, N ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; GLUCOSAMINE;

CLINICAL RESEARCH; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; HUMAN; LETTER; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; CHONDROITIN SULFATES; CLINICAL TRIALS AS TOPIC; DRUG COMBINATIONS; DRUG THERAPY, COMBINATION; GLUCOSAMINE; HUMANS; TREATMENT OUTCOME;

EID: 77954660227     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.02.018     Document Type: Letter

References (8)

1. Jackson C.G., Plaas A.H., Sandy J.D., Hua C., Kim-Rolands S., Barnhill J.G., et al. The human pharmacokinetics of oral ingestion of glucosamine and chondroitin sulfate taken separately or in combination. Osteoarthritis Cartilage 2009, (Epub ahead of print).
2. ®) and its constituents in healthy male volunteers. Osteoarthritis Cartilage 2002, 10:768-777.
3. Volpi N. Oral absorption and bioavailability of ichthyic origin chondroitin sulfate in healthy male volunteers. Osteoarthritis Cartilage 2003, 11:433-441.
4. Du J., White N., Eddington N.D. The bioavailability and pharmacokinetics of glucosamine hydrochloride and chondroitin sulfate after oral and intravenous single dose administration in the horse. Biopharm Drug Dispos 2004, 25:109-116.
5. Barthe L., Woodley J., Lavit M., Przybylski C., Philibert C., Houin G. In vitro intestinal degradation and absorption of chondroitin sulfate, a glycosaminoglycan drug. Arzneimittel-Forschung/Drug Res 2004, 54:286-292.
6. International Medical and Pharmaceutical Information 1984, Ciba-Geigy Limited, Basel, Switzerland. C. Lentner, C. Lentner, A. Wink (Eds.).
7. Jaques L.B., Hiebert L.M., Wice S.M. Evidence from endothelium of gastric absorption of heparin and of dextran sulfates 8000. J Lab Clin Med 1991, 117:122-130.
8. Pecly I.M., Melo-Filho N.M., Mourão P.A. Effects of molecular size and chemical structure on renal and hepatic removal of exogenously administered chondroitin sulfate in rats. Biochim Biophys Acta 2006, 1760:865-876.