Increased NKCC1 expression in arachnoid cysts supports secretory basis for cyst formation

Experimental Neurology

Volumn 224, Issue 2, 2010, Pages 424-428

  Helland, Christian A ^a,b   Aarhus, Mads ^a,b   Knappskog, Per ^a,b   Olsson, Lisa K ^c   Lund Johansen Morten, M ^a,b   Amiry Moghaddam, Mahmood ^c   Wester, Knut ^a,b  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Arachnoid cyst; Blotting (Western); Gene expression profiling; Microscopy (electron); NKCC1 protein (human); Reverse transcriptase polymerase chain reaction

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE 1A1; ADENOSINE TRIPHOSPHATE 1B1; ADENOSINE TRIPHOSPHATE 1B2; CARRIER PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; MESSENGER RNA; NEUROPROTECTIVE AGENT; POTASSIUM CHANNEL KV1.1; POTASSIUM CHANNEL KV1.3; POTASSIUM CHANNEL KV1.6; PROTEIN AQP1; PROTEIN KCNJ13; PROTEIN SLC12A4; PROTEIN SLC12A6; PROTEIN SLC12A7; PROTEIN SLC4A10; PROTEIN SLC4A2; PROTEIN SLC4A7; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1 INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARACHNOID CYST; ARTICLE; CELL MEMBRANE; CEREBROSPINAL FLUID PRODUCTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUID TRANSPORT; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGOLD ELECTRON MICROSCOPY; MALE; MICROARRAY ANALYSIS; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SYNTHESIS; UPREGULATION; WESTERN BLOTTING;

ADULT; ARACHNOID CYSTS; BLOTTING, WESTERN; CHILD; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS;

EID: 77954657419     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.05.002     Document Type: Article

References (29)

1. Aarhus M., Bruland O., Bredholt G., Lybaek H., Husebye E.S., Krossnes B.K., Vedeler C., Wester K., Lund-Johansen M., Knappskog P.M. Microarray analysis reveals down-regulation of the tumour suppressor gene WWOX and up-regulation of the oncogene TYMS in intracranial sporadic meningiomas. J. Neurooncol. 2008, 88:251-259.
2. Aarhus M., Helland C.A., Lund-Johansen M., Wester K., Knappskog P.M. Microarray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts. Cerebrospinal Fluid Res. 2010, 7:6.
3. Amiry-Moghaddam M., Williamson A., Palomba M., Eid T., de Lanerolle N.C., Nagelhus E.A., Adams M.E., Froehner S.C., Agre P., Ottersen O.P. Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of alpha-syntrophin-null mice. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:13615-13620.
4. Brown P.D., Davies S.L., Speake T., Millar I.D. Molecular mechanisms of cerebrospinal fluid production. Neuroscience 2004, 129:957-970.
5. Delpire E., Kaplan M.R., Plotkin M.D., Hebert S.C. The Na-(K)-Cl cotransporter family in the mammalian kidney: molecular identification and function(s). Nephrol. Dial. Transplant. 1996, 11:1967-1973.
6. Dysvik B., Jonassen I. J-Express: exploring gene expression data using Java. Bioinformatics 2001, 17:369-370.
7. Dzhala V.I., Talos D.M., Sdrulla D.A., Brumback A.C., Mathews G.C., Benke T.A., Delpire E., Jensen F.E., Staley K.J. NKCC1 transporter facilitates seizures in the developing brain. Nat. Med. 2005, 11:1205-1213.
8. Eskandary H., Sabba M., Khajehpour F., Eskandari M. Incidental findings in brain computed tomography scans of 3000 head trauma patients. Surg. Neurol. 2005, 63:550-553.
9. Galassi E., Tognetti F., Gaist G., Fagioli L., Frank F., Frank G. CT scan and metrizamide CT cisternography in arachnoid cysts of the middle cranial fossa: classification and pathophysiological aspects. Surg. Neurol. 1982, 17:363-369.
10. Go K.G., Houthoff H.J., Blaauw E.H., Havinga P., Hartsuiker J. Arachnoid cysts of the sylvian fissure. Evidence of fluid secretion. J. Neurosurg. 1984, 60:803-813.
11. Guo L., Lobenhofer E.K., Wang C., Shippy R., Harris S.C., Zhang L., Mei N., Chen T., Herman D., Goodsaid F.M., Hurban P., Phillips K.L., Xu J., Deng X., Sun Y.A., Tong W., Dragan Y.P., Shi L. Rat toxicogenomic study reveals analytical consistency across microarray platforms. Nat. Biotechnol. 2006, 24:1162-1169.
12. Hamann S., Herrera-Perez J.J., Bundgaard M., varez-Leefmans F.J., Zeuthen T. Water permeability of Na+-K+-2Cl- cotransporters in mammalian epithelial cells. J. Physiol. 2005, 568:123-135.
13. Helland C.A., Wester K. A population-based study of intracranial arachnoid cysts - clinical and radiological outcome following surgical cyst decompression in adults. J. Neurol. Neurosurg. Psychiatry 2007, 78(10):1129-1135.
14. Hornig G.W., Zervas N.T. Slit defect of the diaphragma sellae with valve effect: observation of a "slit valve". Neurosurgery 1992, 30:265-267.
15. Katzman G.L., Dagher A.P., Patronas N.J. Incidental findings on brain magnetic resonance imaging from 1000 asymptomatic volunteers. JAMA 1999, 282:36-39.
16. Lebeau C., Hanaoka K., Moore-Hoon M.L., Guggino W.B., Beauwens R., Devuyst O. Basolateral chloride transporters in autosomal dominant polycystic kidney disease. Pflugers Arch. 2002, 444:722-731.
17. MacAulay N., Hamann S., Zeuthen T. Water transport in the brain: role of cotransporters. Neuroscience 2004, 129:1031-1044.
18. Merta M., Rysava R. Brain disorders in autosomal dominant polycystic kidney disease. Sb Lek. 1996, 97:479-485.
19. Payne J.A., Xu J.C., Haas M., Lytle C.Y., Ward D., Forbush B. Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon. J. Biol. Chem. 1995, 270:17977-17985.
20. Rengachary S.S., Watanabe I. Ultrastructure and pathogenesis of intracranial arachnoid cysts. J. Neuropathol. Exp. Neurol. 1981, 40:61-83.
21. Romao E.A., Moyses N.M., Teixeira S.R., Muglia V.F., Vieira-Neto O.M., Dantas M. Renal and extrarenal manifestations of autosomal dominant polycystic kidney disease. Braz. J. Med. Biol. Res. 2006, 39:533-538.
22. Sandberg D.I., Mccomb J.G., Krieger M.D. Chemical analysis of fluid obtained from intracranial arachnoid cysts in pediatric patients. J. Neurosurg. 2005, 103:427-432.
23. Schievink W.I., Huston J., Torres V.E., Marsh W.R. Intracranial cysts in autosomal dominant polycystic kidney disease. J. Neurosurg. 1995, 83:1004-1007.
24. Shi L., Reid L.H., Jones W.D., Shippy R., Warrington J.A., Baker S.C., Collins P.J., de L.F., Kawasaki E.S., Lee K.Y., Luo Y., Sun Y.A., Willey J.C., Setterquist R.A., Fischer G.M., Tong W., Dragan Y.P., Dix D.J., Frueh F.W., Goodsaid F.M., Herman D., Jensen R.V., Johnson C.D., Lobenhofer E.K., Puri R.K., Schrf U., Thierry-Mieg J., Wang C., Wilson M., Wolber P.K., Zhang L., Amur S., Bao W., Barbacioru C.C., Lucas A.B., Bertholet V., Boysen C., Bromley B., Brown D., Brunner A., Canales R., Cao X.M., Cebula T.A., Chen J.J., Cheng J., Chu T.M., Chudin E., Corson J., Corton J.C., Croner L.J., Davies C., Davison T.S., Delenstarr G., Deng X., Dorris D., Eklund A.C., Fan X.H., Fang H., Fulmer-Smentek S., Fuscoe J.C., Gallagher K., Ge W., Guo L., Guo X., Hager J., Haje P.K., Han J., Han T., Harbottle H.C., Harris S.C., Hatchwell E., Hauser C.A., Hester S., Hong H., Hurban P., Jackson S.A., Ji H., Knight C.R., Kuo W.P., LeClerc J.E., Levy S., Li Q.Z., Liu C., Liu Y., Lombardi M.J., Ma Y., Magnuson S.R., Maqsodi B., McDaniel T., Mei N., Myklebost O., Ning B., Novoradovskaya N., Orr M.S., Osborn T.W., Papallo A., Patterson T.A., Perkins R.G., Peters E.H., Peterson R., Philips K.L., Pine P.S., Pusztai L., Qian F., Ren H., Rosen M., Rosenzweig B.A., Samaha R.R., Schena M., Schroth G.P., Shchegrova S., Smith D.D., Staedtler F., Su Z., Sun H., Szallasi Z., Tezak Z., Thierry-Mieg D., Thompson K.L., Tikhonova I., Turpaz Y., Vallanat B., Van C., Walker S.J., Wang S.J., Wang Y., Wolfinger R., Wong A., Wu J., Xiao C., Xie Q., Xu J., Yang W., Zhang L., Zhong S., Zong Y., Slikker W. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat. Biotechnol. 2006, 24:1151-1161.
25. Thomson R.B., Mentone S., Kim R., Earle K., Delpire E., Somlo S., Aronson P.S. Histopathological analysis of renal cystic epithelia in the Pkd2WS25/- mouse model of ADPKD. Am. J. Physiol. Renal. Physiol. 2003, 285:F870-F880.
26. Vernooij M.W., Ikram M.A., Tanghe H.L., Vincent A.J., Hofman A., Krestin G.P., Niessen W.J., Breteler M.M., van der L.A. Incidental findings on brain MRI in the general population. N. Engl. J. Med. 2007, 357:1821-1828.
27. Wester K. Peculiarities of intracranial arachnoid cysts: location, sidedness, and sex distribution in 126 consecutive patients. Neurosurgery 1999, 45:775-779.
28. Zeuthen T. Secondary active transport of water across ventricular cell membrane of choroid plexus epithelium of Necturus maculosus. J. Physiol. 1991, 444:153-173.
29. Zeuthen T. Cotransport of K+, Cl- and H2O by membrane proteins from choroid plexus epithelium of Necturus maculosus. J. Physiol. 1994, 478(Pt 2):203-219.