Fatal progressive multifocal leukoencephalopathy in a patient with non-Hodgkin lymphoma treated with rituximab

Journal of Clinical Virology

Volumn 48, Issue 4, 2010, Pages 291-293

  Paues, Jakob ^a   Vrethem, Magnus ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

JC virus; Leukoencephalopathy; Lymphoma; Non Hodgkin; Polyomavirus infections; Progressive multifocal; Rituximab

Indexed keywords

CIDOFOVIR; CYCLOPHOSPHAMIDE; DOXORUBICIN; LEFLUNOMIDE; PREDNISOLONE; RITUXIMAB; VINCRISTINE; CYTOSTATIC AGENT; IMMUNOLOGIC FACTOR; MONOCLONAL ANTIBODY; VIRUS DNA;

ADULT; ANTIVIRAL THERAPY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID CYTOLOGY; CONFUSION; DEATH; DEMENTIA; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; FEMALE; FEVER; HOSPITAL ADMISSION; HUMAN; JC VIRUS; MULTIPLE CYCLE TREATMENT; NONHODGKIN LYMPHOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PNEUMONIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; TREATMENT WITHDRAWAL; VISUAL IMPAIRMENT; WHITE MATTER; BRAIN; COMPLICATION; FATALITY; ISOLATION AND PURIFICATION; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; LYMPHOMA, NON-HODGKIN; MIDDLE AGED; PATHOLOGY; RADIOGRAPHY; VIROLOGY;

ANTIBODIES, MONOCLONAL; BRAIN; CEREBROSPINAL FLUID; CYTOSTATIC AGENTS; DNA, VIRAL; FATAL OUTCOME; FEMALE; HUMANS; IMMUNOLOGIC FACTORS; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; LYMPHOMA, NON-HODGKIN; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; ANTIBODIES, MONOCLONAL, MURINE-DERIVED;

EID: 77954656243     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2010.05.003     Document Type: Article

References (21)

1. Carson K.R., Focosi D., Major E.O., Petrini M., Richey E.A., West D.P., et al. Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) project. Lancet Oncol 2009, 10:816-824.
2. Tan C.S., Koralnik I.J. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. Lancet Neurol 2010, 9:425-437.
3. Carson K.R., Evens A.M., Richey E.A., Habermann T.M., Focosi D., Seymour J.F., et al. Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project. Blood 2009, 113:4834-4840.
4. Padgett B.L., Walker D.L., ZuRhein G.M., Eckroade R.J., Dessel B.H. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1971, 1:1257-1260.
5. Koralnik I.J. Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name?. Ann Neurol 2006, 60:162-173.
6. Bofill-Mas S., Pina S., Girones R. Documenting the epidemiologic patterns of polyomaviruses in human populations by studying their presence in urban sewage. Appl Environ Microbiol 2000, 66:238-245.
7. Wei G., Liu C.K., Atwood W.J. JC virus binds to primary human glial cells, tonsillar stromal cells, and B-lymphocytes, but not to T lymphocytes. J Neurovirol 2000, 6:127-136.
8. Monaco M.C., Jensen P.N., Hou J., Durham L.C., Major E.O. Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. J Virol 1998, 72:9918-9923.
9. Egli A., Infanti L., Dumoulin A., Buser A., Samaridis J., Stebler C., et al. Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors. J Infect Dis 2009, 199:837-846.
10. Knowles W.A., Pipkin P., Andrews N., Vyse A., Minor P., Brown D.W., et al. Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. J Med Virol 2003, 71:115-123.
11. Tan C.S., Dezube B.J., Bhargava P., Autissier P., Wuthrich C., Miller J., et al. Detection of JC virus DNA and proteins in the bone marrow of HIV-positive and HIV-negative patients: implications for viral latency and neurotropic transformation. J Infect Dis 2009, 199:881-888.
12. Perez-Liz G., Del Valle L., Gentilella A., Croul S., Khalili K. Detection of JC virus DNA fragments but not proteins in normal brain tissue. Ann Neurol 2008, 64:379-387.
13. Eash S., Tavares R., Stopa E.G., Robbins S.H., Brossay L., Atwood W.J. Differential distribution of the JC virus receptor-type sialic acid in normal human tissues. Am J Pathol 2004, 164:419-428.
14. Koralnik I.J., Boden D., Mai V.X., Lord C.I., Letvin N.L. JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy. Neurology 1999, 52:253-260.
15. Bialasiewicz S., Whiley D.M., Lambert S.B., Nissen M.D., Sloots T.P. Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples. J Clin Virol 2009, 45:249-254.
16. Swanson P.A., Lukacher A.E., Szomolanyi-Tsuda E. Immunity to polyomavirus infection: the polyomavirus-mouse model. Semin Cancer Biol 2009, 19:244-251.
17. Aksoy S., Harputluoglu H., Kilickap S., Dede D.S., Dizdar O., Altundag K., et al. Rituximab-related viral infections in lymphoma patients. Leuk Lymphoma 2007, 48:1307-1312.
18. Anolik J.H., Friedberg J.W., Zheng B., Barnard J., Owen T., Cushing E., et al. B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny. Clin Immunol 2007, 122:139-145.
19. Teramoto T., Kaneko H., Funato M., Sawa H., Nagashima K., Hirose Y., et al. Progressive multifocal leukoencephalopathy in a patient with X-linked agammaglobulinemia. Scand J Infect Dis 2003, 35:909-910.
20. Hickey W.F. Basic principles of immunological surveillance of the normal central nervous system. Glia 2001, 36:118-124.
21. Lindå H., von Heijne A., Major E.O., Ryschkewitsch C., Berg J., Olsson T., et al. Progressive multifocal leukoencephalopathy after natalizumab monotherapy. N Engl J Med 2009, 361:1081-1087.