Antispermatogenic and antifertility effect of Pegaga (Centella asiatica L) on the testis of male Sprague-Dawley rats

Clinica Terapeutica

Volumn 161, Issue 3, 2010, Pages 235-239

  Yunianto, I ^a   Das, S ^a   Mat Noor, Mahanem ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

Author keywords

Centella asiatica L; Motility; Sperm count; Testis; Testosterone

Indexed keywords

ANTISPERMATOGENIC AGENT; CENTELLA ASIATICA EXTRACT; CONTRACEPTIVE AGENT; TESTOSTERONE;

ADULT ANIMAL; ANIMAL EXPERIMENT; ARTICLE; CENTELLA ASIATICA; CONTROLLED STUDY; DRUG EFFECT; HISTOLOGY; MALE; NONHUMAN; RAT; SEMINIFEROUS TUBULE EPITHELIUM; SPERMATOCYTE; SPERMATOZOON; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; SPRAGUE DAWLEY RAT; TESTIS;

ANIMALS; FERTILITY; MALE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SPERM COUNT; SPERM MOTILITY; TESTIS; TESTOSTERONE; TRITERPENES;

EID: 77954651247     PISSN: 00099074     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Qureshi AA, Sanghai DB, Padgilwar SS. Herbal options for contraception: a review. Pharmacog Mag 2005; 2:204-14
2. Sarkar M, Gangopadhyay P, Basak B, et al. The reversible antifertility effect of Piper betle Linn. On Swiss albino male mice. Contraception 2000; 62:271-74
3. Inamdar PK, Yeole RD, Ghogare AB, et al. Determination of biologically active constituents in Centella asiatica. J Chromatogr 1996; 742:127-30
4. Jaganath IB, Ng LT. HERBS: the green pharmacy of Malaysia. Vinpress Sdn. Bhd. Malaysia 2000; 21-33. Website: http://paracite.eprints.org/cgi-bin/openurl. Last accessed on 31.7.09
5. Dutta T, Basu UP. Crude extract of Centella asiatica and products derived from its glycosides as oral antifertility effect. Indian J Exp Biol 1968; 28:181-2
6. Houghton PJ, Raman A. Laboratory handbook for the fractionation of natural extract. Chapman & Hall, London, 1998
7. Prasad MRN, Chinoy NJ, Kadam KM. Changes in succinic dehydrogenase levels in the rat epididymis under normal and altered physiologic conditions. Fertil Steril 1972; 23: 186-90
8. WHO. Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Cambridge University Press, New York, 1999
9. Daniel JC. Methods in Mammalian Embryology. Freeman WN and Company, San Francisco, 1971
10. Humason GL. Animal tissue techniques. Freeman WN & Company, San Francisco, 1979
11. Phillips DM. Spermiogenesis in animals. Academic Press, Inc, London, 1974
12. Fox SI. Human Physiology. McGraw Hill, New York, 2006
13. Mali PC, Ansari AS, Chaturvedi M. Antifertility effect of chronically administered Martynia annua root extract on male rats. J Ethnopharmacol 2002; 82:61-7 (Pubitemid 35292032)
14. Wei LS, Musa N, Sengm CT, et al. Antimicrobial properties of tropical plants against 12 pathogenic bacteria isolated from aquatic organisms. African J Biotechnol 2008; 7:2275-8 (Pubitemid 351977847)
15. Padashetty SA, Mishra SH. Effect of terpenoidal fraction of Echinops echinatus roots on reproductive parameters of male rats. J Nat Med 2007; 61:452-7