Optimizing the treatment of haemophilia B: Laboratory and clinical perspectives

Haemophilia

Volumn 16, Issue SUPPL. 6, 2010, Pages 1-2

  Aledort, Louis M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Chromogenic assays; Clotting assays; Factor IX; Haemophilia B; Pharmacokinetics; Prophylaxis

Indexed keywords

BLOOD CLOTTING FACTOR 9; RECOMBINANT BLOOD CLOTTING FACTOR 9;

BLEEDING; CLINICAL FEATURE; DISEASE SEVERITY; EDITORIAL; HEMOPHILIA B; HEMOSTASIS; HUMAN; PRIORITY JOURNAL;

ADULT; CHILD; FACTOR IX; HEMOPHILIA B; HEMORRHAGE; HUMANS; RECOMBINANT PROTEINS;

EID: 77954648162     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2010.02298.x     Document Type: Editorial

References (11)

1. Srivastava A, Giangrande P, Poon MC, Chua M, McCraw A, Wiedel J. Guidelines for the Management of Hemophilia http://www.wfh.org/index.asp?lang=EN, World Federation of Hemophilia web site, published 2005. Available at
2. White GC, Beebe A, Nielsen B. Recombinant factor IX. Thromb Haemost 1997, 78:261-5.
3. Ewenstein BM, Joist JH, Shapiro AD. Pharmacokinetic analysis of plasma-derived and recombinant F IX concentrates in previously treated patients with moderate or severe hemophilia B. Transfusion 2002, 42:190-7.
4. Poon MC. Pharmacokinetics of factors IX, recombinant activated factor VII and factor XIII. Haemophilia 2006, 12(Suppl. 4):61-9.
5. Bjorkman S, Folkesson A, Berntorp E. In vivo recovery of factor VIII and factor IX: intra- and interindividual variance in a clinical setting. Haemophilia 2007, 13:2-8.
6. Zakarija A. Factor IX replacement in surgery and prophylaxis. Blood Coagul Fibrinolysis 2004, 15(Suppl. 2):S5-7.
7. Quon D. Personal communication. 2009
8. Schulman S, Eelde A, Holmstrom M, Stahlberg G, Odeberg J, Blomback M. Validation of a composite score for clinical severity of hemophilia. J Thromb Haemost 2008, 6:1113-21.
9. Tagariello G, Iorio A, Santagostino E. Comparison of the rates of joint arthroplasty in patients with severe factor VIII and IX deficiency: an index of different clinical severity of the 2 coagulation disorders. Blood 2009, 114:779-84.
10. Makris M. Is VIII worse than IX? Blood 2009, 114:750-1.
11. Pai KM, Walker I, Almonte T, Chan AK, Sek J, Decker K. Comparing bleed frequency and factor concentrate use between haemophilia A and haemophilia B. J Thromb Haemost 2005, 3. (Suppl. 1), Abstract P0807