In169, A New Class 1 Integron that Encoded blaIMP-18 in a Multidrug-Resistant Pseudomonas aeruginosa Isolate from Mexico

Archives of Medical Research

Volumn 41, Issue 4, 2010, Pages 235-239

  Sánchez Martinez, Guillermina ^a   Garza Ramos, Ulises Jesús ^a   Reyna Flores, Fernando Luis ^a   Gaytán Martínez, Jesús ^b   Lorenzo Bautista, Isaí Guillermo ^b   Silva Sanchez, Jesús ^a  

^a INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Carbapenem resistance; Classs 1 integron; IMP 18; Metallo lactamase; P. aeruginosa

Indexed keywords

AGAR; IMIPENEM; METALLO BETA LACTAMASE; ANTIINFECTIVE AGENT; PRIMER DNA;

ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; DILUTION; DNA PROBE; DNA SEQUENCE; ENZYME SYNTHESIS; HOSPITAL; INTEGRON; MEXICO; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; PULSED FIELD GEL ELECTROPHORESIS; SOUTHERN BLOTTING; ANTIBIOTIC RESISTANCE; DRUG EFFECTS; GENETICS;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DNA PRIMERS; DRUG RESISTANCE, MICROBIAL; DRUG RESISTANCE, MULTIPLE; ELECTROPHORESIS, GEL, PULSED-FIELD; INTEGRONS; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA;

EID: 77954635542     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2010.05.006     Document Type: Article

References (18)

1. Paterson D.L., Bonomo R.A. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 2005, 18:657-686.
2. Mendes R.E., Castanheira M., Toleman M.A., et al. Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. Antimicrob Agents Chemother 2007, 51:2611-2614.
3. Queenan A.M., Bush K. Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev 2007, 20:440-458.
4. Garza-Ramos U., Morfin-Otero R., Sader H.S., et al. Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. Antimicrob Agents Chemother 2008, 52:2943-2946.
5. Garza-Ramos U., Morfin-Otero R., Sader H.S., et al. Metallo-beta-lactamase IMP-18 is located in a class 1 integron (In96) in a clinical isolate of Pseudomonas aeruginosa from Mexico. Int J Antimicrob Agents 2008, 31:78-80.
6. Garza-Ramos U., Tinoco P., Rojas T., et al. Molecular characterization of integron class 1 (In196) encoding the VIM-2 metallo-beta-lactamase of Pseudomonas aeruginosa isolated from a hospital environment. J Chemother 2009, 21:590-591.
7. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing. Document M100-S18. 2008 2008, Clinical and Laboratory Standards Institute, Wayne, PA.
8. Levesque C., Piche L., Larose C., et al. PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob Agents Chemother 1995, 39:185-191.
9. Adrian P.V., Thomson C.J., Klugman K.P., et al. New gene cassettes for trimethoprim resistance, dfr13, and streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron. Antimicrob Agents Chemother 2000, 44:355-361.
10. Kazama H., Hamashima H., Sasatsu M., et al. Distribution of the antiseptic-resistance gene qacE delta 1 in gram-positive bacteria. FEMS Microbiol Lett 1998, 165:295-299.
11. Kieser T. Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coli. Plasmid 1984, 12:19-36.
12. Miller J. Experiments in Molecular Genetics 1972, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
13. Kaufmann M.E. Pulse-field gel electrophoresis. Methods Mol Med 1998, 15:17-31.
14. Tenover F.C., Arbeit R.D., Goering R.V., et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995, 33:2233-2239.
15. Stokes H.W., O'Gorman D.B., Recchia G.D., et al. Structure and function of 59-base element recombination sites associated with mobile gene cassettes. Mol Microbiol 1997, 26:731-745.
16. Drawz S.M., Bonomo R.A. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev 2010, 23:160-201.
17. Wolter D.J., Khalaf N., Robledo I.E., et al. Surveillance of carbapenem-resistant Pseudomonas aeruginosa isolates from Puerto Rican Medical Center Hospitals: dissemination of KPC and IMP-18 beta-lactamases. Antimicrob Agents Chemother 2009, 53:1660-1664.
18. Kumar A., Schweizer H.P. Bacterial resistance to antibiotics: active efflux and reduced uptake. Adv Drug Deliv Rev 2005, 7:1486-1513.