Fast quantitative single-molecule detection at ultralow concentrations

Analytical Chemistry

Volumn 82, Issue 14, 2010, Pages 6299-6302

  Haas, Philippe ^a   Then, Patrick ^b   Wild, Andreas ^a   Grange, Wilfried ^c   Zorman, Sylvain ^c   Hegner, Martin ^d   Calame, Michel ^e   Aebi, Ueli ^f   Flammer, Josef ^g   Hecht, Bert ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c INSTITUT JACQUES MONOD   (France)

^d TRINITY COLLEGE DUBLIN   (Ireland)

^e Department of Physics ^*  (Switzerland)

^f UNIVERSITY OF BASEL   (Switzerland)

^g UNIVERSITY EYE CLINIC   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DETECTABILITY; FLUORESCENCE ASSAY; MEASUREMENT TIME; MEDICAL DIAGNOSTICS; POINT OF CARE; SINGLE-MODE OPTICAL FIBER; SINGLE-MOLECULE; SINGLE-MOLECULE DETECTION; ULTRASENSITIVE;

FLUORESCENCE; OPTICAL FIBERS;

MOLECULES;

FLUORESCENT DYE; QUANTUM DOT;

ARTICLE; DIFFUSION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HOSPITAL INFORMATION SYSTEM; METHODOLOGY; SPECTROFLUOROMETRY; PROCEDURES;

DIFFUSION; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; POINT-OF-CARE SYSTEMS; QUANTUM DOTS; SPECTROMETRY, FLUORESCENCE;

EID: 77954635157     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac100779c     Document Type: Article

References (17)

1. Kim, S. A., Heinze, K. G., and Schwille, P. Nat. Methods 2007, 4, 963-973
2. Zander, C., Enderlein, J., and Keller, R. Single Molecule Detection in Solution: Methods and Applications; Wiley-VCH: Berlin, Germany, 2002.
3. Sauer, M., Drexhage, K., Zander, C., and Wolfrum, J. Chem. Phys. Lett. 1996, 254, 223-228
4. Wolfbeis, O. Anal. Chem. 2000, 72, 81R-89R
5. Schena, M., Shalon, D., Davis, R., and Brown, P. Science 1995, 270, 467
6. Tan, X. and Liu, W. Anal. Chem. 1999, 71, 5054-5059
7. Walt, F., Steemers, J., and Ferguson, J. Nat. Biotechnol. 2000, 18, 91-94
8. Ferguson, J. and Boles, T. Nat. Biotechnol. 1996, 14, 1681-1684
9. Hecht, B., Haas, P., Wild, A., Hegner, M., and Calame, M. Single analyte molecule detection by fibre fluorescence probe. U.S. Patent 7,657,133, February 2, 2010.
10. Lukosz, W. and Kunz, R. J. Opt. Soc. Am. 1977, 67, 1615-1619
11. Novotny, L. and Hecht, B. Principles of Nano-Optics; Cambridge University Press: Cambridge, U.K., 2006.
12. Grange, W., Haas, P., Wild, A., Calame, M., Hegner, M., and Hecht, B. J. Phys. Chem. B 2008, 112, 7140-7144
13. Munson, B. R., Young, D. F., and Okiishi, T. H. Fundamentals of Fluid Mechanics; John Wiley & Sons, Inc: New York, 2006.
14. Soper, S. A., Mattingly, Q. L., and Vegunta, P. Anal. Chem. 1993, 65, 740-747
15. Schaffer, J., Volkmer, A., Eggeling, C., Subramaniam, V., Striker, G., and Seidel, C. J. Phys. Chem. A 1999, 103, 331-336
16. Zander, C., Sauer, M., Drexhage, K., Ko, D., Schulz, A., Wolfrum, J., Brand, L., Eggeling, C., and Seidel, C. Appl. Phys. B: Laser Opt. 1996, 63, 517-523
17. Nie, S., Chiu, D. T., and Zare, R. N. Anal. Chem. 1995, 67, 2849-2857