메뉴 건너뛰기




Volumn 78, Issue 2, 2010, Pages 259-274

Acute administration of clozapine and risperidone altered dopamine metabolism more in rat caudate than in nucleus accumbens: A dose-response relationship

Author keywords

Atypical antipsychotics; Dopamine D2 receptors; Extrapyramidal side effects; Schizophrenia; Serotonin 1AReceptors

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; CLOZAPINE; DIHYDROXYPHENYLACETIC ACID; HOMOVANILLIC ACID; RISPERIDONE; SEROTONIN; TRYPTOPHAN;

EID: 77954634390     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.0907-20     Document Type: Article
Times cited : (3)

References (36)
  • 1
    • 50349086333 scopus 로고    scopus 로고
    • Neuropharmacology of second-generation antipsychotic drugs: A validity of the serotonin-dopamine hypothesis
    • 10.1016/S0079-6123(08)00910-2
    • Kuroki T, Nagao N, Nakahara T. Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine hypothesis. Prog Brain Res. 2008; 172: 199-212. doi:10.1016/S0079-6123(08)00910-2
    • (2008) Prog Brain Res , vol.172 , pp. 199-212
    • Kuroki, T.1    Nagao, N.2    Nakahara, T.3
  • 2
    • 50349091367 scopus 로고    scopus 로고
    • Alterations of dopamine and serotonin transmission in schizophrenia
    • 10.1016/S0079-6123(08)00906-0
    • Remington G. Alterations of dopamine and serotonin transmission in schizophrenia. Prog Brain Res. 2008; 172: 117-140. doi:10.1016/S0079-6123(08)00906-0
    • (2008) Prog Brain Res , vol.172 , pp. 117-140
    • Remington, G.1
  • 3
    • 50349096587 scopus 로고    scopus 로고
    • In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
    • 10.1016/S0079-6123(08)00909-6
    • Meltzer HY, Huang M. In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems. Prog Brain Res. 2008; 172: 177-197. doi:10.1016/S0079-6123(08)00909-6
    • (2008) Prog Brain Res , vol.172 , pp. 177-197
    • Meltzer, H.Y.1    Huang, M.2
  • 4
    • 0028176855 scopus 로고
    • 2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerized tomography study
    • 10.1192/bjp.164.1.16
    • Pilowsky LS, Costa DC, Ell PJ, Verhoeff NP, Murray RM, Kerwin RW. D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerized tomography study. Br J Psychiatry. 1994; 164: 16-26. doi:10.1192/bjp.164.1.16
    • (1994) Br J Psychiatry , vol.164 , pp. 16-26
    • Pilowsky, L.S.1    Costa, D.C.2    Ell, P.J.3    Verhoeff, N.P.4    Murray, R.M.5    Kerwin, R.W.6
  • 5
    • 70349124929 scopus 로고    scopus 로고
    • Antipsychotic drugs for first-episode schizophrenia: A comparative review
    • 10.2165/11314280-000000000-00000
    • Salimi K, Jarskog LF, Lieberman JA. Antipsychotic drugs for first-episode schizophrenia: a comparative review. CNS Drugs. 2009; 23: 837-855. doi:10.2165/11314280-000000000-00000
    • (2009) CNS Drugs , vol.23 , pp. 837-855
    • Salimi, K.1    Jarskog, L.F.2    Lieberman, J.A.3
  • 6
    • 33947647367 scopus 로고    scopus 로고
    • Effects of risperidone on dopamine receptor subtypes in developing rat brain
    • 10.1016/j.euroneuro.2006.10.004
    • Moran-Gates T, Grady C, Shik Park Y, Baldessarini RJ, Tarazi FI. Effects of risperidone on dopamine receptor subtypes in developing rat brain. Eur Neuropsychopharmacol. 2007; 17: 448-455. doi:10.1016/j.euroneuro.2006.10.004
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 448-455
    • Moran-Gates, T.1    Grady, C.2    Park, S.Y.3    Baldessarini, R.J.4    Tarazi, F.I.5
  • 7
    • 0030911562 scopus 로고    scopus 로고
    • Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal ortex: Role of alpha 2-adrenoceptor antagonism
    • 10.1016/S0893-133X(97)00002-X
    • Hertel P, Nomikos GG, Schilström B, Arborelius L, Svensson TH. Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal ortex: role of alpha 2-adrenoceptor antagonism. Neuropsychopharmacology. 1997; 17: 44-55. doi:10.1016/S0893-133X(97)00002-X
    • (1997) Neuropsychopharmacology , vol.17 , pp. 44-55
    • Hertel, P.1    Nomikos, G.G.2    Schilström, B.3    Arborelius, L.4    Svensson, T.H.5
  • 8
    • 0031564651 scopus 로고    scopus 로고
    • Effects of risperidone, clozapine and haloperidol on extracellular recordings of substantia nigra reticulata neurons of the rat brain
    • 10.1016/S0014-2999(97)00054-X
    • Bruggeman R, Westerink BH, Timmerman W. Effects of risperidone, clozapine and haloperidol on extracellular recordings of substantia nigra reticulata neurons of the rat brain. Eur J Pharmacol. 1997; 324: 49-56. doi:10.1016/S0014-2999(97)00054-X
    • (1997) Eur J Pharmacol , vol.324 , pp. 49-56
    • Bruggeman, R.1    Westerink, B.H.2    Timmerman, W.3
  • 9
    • 0030063466 scopus 로고    scopus 로고
    • 1A receptors
    • 10.1016/0028-3908(95)00170-0
    • Newman A, Chaput C, Verriele L. Millan MJ. Clozapine is a partial agonist at cloned human serotonin 5-HT1A receptors. Neuropharmacology. 1996; 35: 119-121. doi:10.1016/0028-3908(95)00170-0
    • (1996) Neuropharmacology , vol.35 , pp. 119-121
    • Newman, A.1    Chaput, C.2    Verriele, L.3    Millan, M.J.4
  • 10
    • 0029881945 scopus 로고    scopus 로고
    • Risperidone: Regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain
    • 10.1007/BF02245607
    • Hertel P, Nomikos GG, Iurlo M, Svensson TH. Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain. Psychopharmacology (Berl). 1996; 124: 74-86. doi:10.1007/BF02245607
    • (1996) Psychopharmacology (Berl) , vol.124 , pp. 74-86
    • Hertel, P.1    Nomikos, G.G.2    Iurlo, M.3    Svensson, T.H.4
  • 12
    • 55049106809 scopus 로고    scopus 로고
    • Upcoming agents for the treatment of schizophrenia: Mechanism of action, efficacy and tolerability
    • 10.2165/0003495-200868160-00002
    • Bishara D, Taylor D. Upcoming agents for the treatment of schizophrenia: mechanism of action, efficacy and tolerability. Drugs. 2008; 68: 2269-2292. doi:10.2165/0003495-200868160-00002
    • (2008) Drugs , vol.68 , pp. 2269-2292
    • Bishara, D.1    Taylor, D.2
  • 13
    • 0028331326 scopus 로고
    • The new atypical antipsychotics. A lack of extrapyramidal side-effects and new routes in schizophrenia research
    • 10.1192/bjp.164.2.141
    • Kerwin RW. The new atypical antipsychotics. A lack of extrapyramidal side-effects and new routes in schizophrenia research. Br J Psychiatry. 1994; 164: 141-148. doi:10.1192/bjp.164.2.141
    • (1994) Br J Psychiatry , vol.164 , pp. 141-148
    • Kerwin, R.W.1
  • 14
    • 0035675612 scopus 로고    scopus 로고
    • 2 dopamine receptor blockade with haloperidol or new antipsychotic drugs in patients with schizophrenia
    • 10.1192/bjp.179.6.503
    • Xiberas X, Martinot JL, Mallet L, Artiges E, Loc'H C, Mazière B, Paillère-Martinot ML. Extrastriatal and striatal D2 dopamine receptor blockade with haloperidol or new antipsychotic drugs in patients with schizophrenia. Br J Psychiatry. 2001; 179: 503-508. doi:10.1192/bjp.179.6.503
    • (2001) Br J Psychiatry , vol.179 , pp. 503-508
    • Xiberas, X.1    Martinot, J.L.2    Mallet, L.3    Artiges, E.4
  • 15
    • 0027341623 scopus 로고
    • 2 dopamine receptor occupancy in the living human brain. A PET study with risperidone
    • 10.1007/BF02251280
    • Nyberg S, Farde L, Eriksson L, Halldin C, Eriksson B. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology. 1993; 110: 265-272. doi:10.1007/BF02251280
    • (1993) Psychopharmacology , vol.110 , pp. 265-272
    • Nyberg, S.1    Farde, L.2    Eriksson, L.3    Halldin, C.4    Eriksson, B.5
  • 16
    • 58049157203 scopus 로고    scopus 로고
    • Second-generation versus first-generation antipsychotic drugs for schizophrenia: A meta-analysis
    • 10.1016/S0140-6736(08)61764-X
    • Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet. 2009; 373 (9657): 31-41. doi:10.1016/S0140-6736(08)61764-X
    • (2009) Lancet , vol.373 , Issue.9657 , pp. 31-41
    • Leucht, S.1    Corves, C.2    Arbter, D.3    Engel, R.R.4    Li, C.5    Davis, J.M.6
  • 17
    • 0031596816 scopus 로고    scopus 로고
    • 2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study
    • 10.1007/s002130050579
    • Kasper S, Tauscher J, Küfferle B, Barnas C, Hesselmann B, Asenbaum S, Podreka I, Brücke, T. Sertindole and dopamine D2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study. Psychopharmacology. 1998; 136: 367-373. doi:10.1007/s002130050579
    • (1998) Psychopharmacology , vol.136 , pp. 367-373
    • Kasper, S.1    Tauscher, J.2    Küfferle, B.3    Barnas, C.4    Hesselmann, B.5    Asenbaum, S.6    Podreka, I.7    Brücke, T.8
  • 18
    • 17144447454 scopus 로고    scopus 로고
    • Differences in the effects of haloperidol and clozapine on brain serotonin and dopamine metabolism and on tests related to extrapyramidal functions in rats
    • PMid:12218936
    • Haleem DJ, Batool F, Khan NH, Kamil N, Ali O, Saify ZS, Haleem MA. Differences in the effects of haloperidol and clozapine on brain serotonin and dopamine metabolism and on tests related to extrapyramidal functions in rats. Med Sci Monit. 2002; 8: BR354-BR361. PMid:12218936
    • (2002) Med Sci Monit , vol.8
    • Haleem, D.J.1    Batool, F.2    Khan, N.H.3    Kamil, N.4    Ali, O.5    Saify, Z.S.6    Haleem, M.A.7
  • 19
    • 64149090605 scopus 로고    scopus 로고
    • Dietary supplementations of amino acids: Evidence for enhanced serotonergic functions following haloperidol withdrawal in rat medial prefrontal cortex
    • PMid:19268010
    • Batool F, Ahmed S, Haleem DJ. Dietary supplementations of amino acids: evidence for enhanced serotonergic functions following haloperidol withdrawal in rat medial prefrontal cortex. J Coll Physicians Surg Pak. 2009; 19: 139-145. PMid:19268010
    • (2009) J Coll Physicians Surg Pak , vol.19 , pp. 139-145
    • Batool, F.1    Ahmed, S.2    Haleem, D.J.3
  • 20
    • 0024466603 scopus 로고
    • 2 pKi values
    • PMid:2571717
    • Meltzer HY, Matsubara S, Lee JC. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D1, D2 and serotonin2 pKi values. J Pharmacol Exp Ther. 1989; 251: 238-246. PMid:2571717
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 238-246
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 21
    • 0035890854 scopus 로고    scopus 로고
    • Antipsychotic drugs and neuroplasticity: Insights into the treatment and neurobiology of schizophrenia
    • 10.1016/S0006-3223(01)01267-7
    • Konradi C, Heckers S. Antipsychotic drugs and neuroplasticity: insights into the treatment and neurobiology of schizophrenia. Biol Psychiatry. 2001; 50: 729-742. doi:10.1016/S0006-3223(01)01267-7
    • (2001) Biol Psychiatry , vol.50 , pp. 729-742
    • Konradi, C.1    Heckers, S.2
  • 22
    • 0033624208 scopus 로고    scopus 로고
    • 2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats
    • 10.1007/s002130000466
    • Wadenberg ML, Kapur S, Soliman A, Jones C, Vaccarino F. Dopamine D2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats. Psychopharmacology. 2000; 150: 422-429. doi:10.1007/s002130000466
    • (2000) Psychopharmacology , vol.150 , pp. 422-429
    • Wadenberg, M.L.1    Kapur, S.2    Soliman, A.3    Jones, C.4    Vaccarino, F.5
  • 23
    • 0018908307 scopus 로고
    • Changes in rat striatal dopamine turnover and receptor activity during one year neuroleptic administration
    • 10.1016/0014-2999(80)90437-9
    • Clow A, Theodorou A, Jenner P, Marsden CD. Changes in rat striatal dopamine turnover and receptor activity during one year neuroleptic administration. Eur J Pharmacol. 1980; 63: 135-144. doi:10.1016/0014-2999(80)90437-9
    • (1980) Eur J Pharmacol , vol.63 , pp. 135-144
    • Clow, A.1    Theodorou, A.2    Jenner, P.3    Marsden, C.D.4
  • 24
    • 0032817821 scopus 로고    scopus 로고
    • 3 dopamine receptors by typical antipsychotic drugs. [123I] epidepride single photon emission tomography (SPET) study
    • 10.1192/bjp.175.3.231
    • Bigliani V, Mulligan RS, Acton PD, Visvikis D, Ellm PJ, Stephenson C, Kerwin RW, Pilowsky LS. In vivo occupancy of striatal and temporal cortical D2/D3 dopamine receptors by typical antipsychotic drugs. [123I] epidepride single photon emission tomography (SPET) study. Br J Psychiatry. 1999; 175: 231-238. doi:10.1192/bjp.175.3.231
    • (1999) Br J Psychiatry , vol.175 , pp. 231-238
    • Bigliani, V.1    Mulligan, R.S.2    Acton, P.D.3    Visvikis, D.4    Ellm, P.J.5    Stephenson, C.6    Kerwin, R.W.7    Pilowsky, L.S.8
  • 25
    • 0024430178 scopus 로고
    • 2 dopamine receptor occupancy during treatment with conventional and atypical neuroleptics
    • 10.1007/BF00442555
    • Farde L, Wiesel FA, Nordström AL, Sedvall G. D1 and D2 dopamine receptor occupancy during treatment with conventional and atypical neuroleptics. Psychopharmacology. 1989; 99: S28-S31. doi:10.1007/BF00442555
    • (1989) Psychopharmacology , vol.99
    • Farde, L.1    Wiesel, F.A.2    Nordström, A.L.3    Sedvall, G.4
  • 27
    • 12244284609 scopus 로고    scopus 로고
    • 3 receptor occupancy by risperidone: A [123I]-epidepride SPET study
    • 10.1097/00004714-200302000-00002
    • Bressan RA, Erlandsson K, Jones HM, Mulligan RS, Ell PJ, Pilowsky LS. Optimizing limbic selective D2/D3 receptor occupancy by risperidone: a [123I]-epidepride SPET study. J Clin Psychopharmacol. 2003; 23: 5-14. doi:10.1097/00004714-200302000-00002
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 5-14
    • Bressan, R.A.1    Erlandsson, K.2    Jones, H.M.3    Mulligan, R.S.4    Ell, P.J.5    Pilowsky, L.S.6
  • 28
    • 0035094264 scopus 로고    scopus 로고
    • 2 receptor explain the action of atypical antipsychotics?: A new hypothesis
    • 10.1176/appi.ajp.158.3.360
    • Kapur S, Seeman P. Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics?: A new hypothesis. Am J Psychiatry. 2001; 158: 360-369. doi:10.1176/appi.ajp.158.3.360
    • (2001) Am J Psychiatry , vol.158 , pp. 360-369
    • Kapur, S.1    Seeman, P.2
  • 29
    • 50349096587 scopus 로고    scopus 로고
    • In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
    • 10.1016/S0079-6123(08)00909-6
    • Meltzer HY, Huang M. In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems. Prog Brain Res. 2008; 172: 177-197. doi:10.1016/S0079-6123(08)00909-6
    • (2008) Prog Brain Res , vol.172 , pp. 177-197
    • Meltzer, H.Y.1    Huang, M.2
  • 30
    • 52949121824 scopus 로고    scopus 로고
    • Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine
    • 10.1016/j.schres.2008.07.005
    • Natesan S, Reckless GE, Barlow KB, Nobrega JN, Kapur S. Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine. Schizophr Res. 2008; 105: 224-235. doi:10.1016/j.schres.2008.07.005
    • (2008) Schizophr Res , vol.105 , pp. 224-235
    • Natesan, S.1    Reckless, G.E.2    Barlow, K.B.3    Nobrega, J.N.4    Kapur, S.5
  • 31
    • 0025242104 scopus 로고
    • The effect of serotonergic agents on haloperidol-induced catalepsy
    • 10.1016/0024-3205(90)90365-X
    • Hicks PB. The effect of serotonergic agents on haloperidol-induced catalepsy. Life Sci. 1990; 47: 1609-1615. doi:10.1016/0024-3205(90)90365-X
    • (1990) Life Sci , vol.47 , pp. 1609-1615
    • Hicks, P.B.1
  • 32
    • 0028933729 scopus 로고
    • A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors
    • 10.1097/00004850-199503000-00003
    • He H, Richardson JS. A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors. Int Clin Psychopharmacol. 1995; 10: 19-30. doi:10.1097/00004850-199503000-00003
    • (1995) Int Clin Psychopharmacol , vol.10 , pp. 19-30
    • He, H.1    Richardson, J.S.2
  • 33
    • 58149346218 scopus 로고    scopus 로고
    • 1A receptors in the action of antipsychotic drugs: Comparison of prepulse inhibition studies in mice and rats and relevance for human pharmacology
    • 10.1097/FBP.0b013e32830cd822
    • Gogos A, Bogeski M, van den Buuse M. Role of serotonin1A receptors in the action of antipsychotic drugs: comparison of prepulse inhibition studies in mice and rats and relevance for human pharmacology. Behav Pharmacol. 2008; 19: 548-561. doi:10.1097/FBP.0b013e32830cd822
    • (2008) Behav Pharmacol , vol.19 , pp. 548-561
    • Gogos, A.1    Bogeski, M.2    van den Buuse, M.3
  • 34
    • 34250729737 scopus 로고    scopus 로고
    • Neurochemical and behavioral effects of 8-OH-DPAT following exposure to restraint stress in rats
    • PMid:17556795
    • Samad N, Batool F, Haleem DJ. Neurochemical and behavioral effects of 8-OH-DPAT following exposure to restraint stress in rats. Pharmacol Rep. 2007; 59: 173-180. PMid:17556795
    • (2007) Pharmacol Rep , vol.59 , pp. 173-180
    • Samad, N.1    Batool, F.2    Haleem, D.J.3
  • 35
    • 34249805403 scopus 로고    scopus 로고
    • Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats
    • 10.1016/j.pbb.2007.04.007
    • Haleem DJ, Samad N, Haleem MA. Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats. Pharmacol Biochem Behav. 2007; 87: 115-121. doi:10.1016/j.pbb.2007.04.007
    • (2007) Pharmacol Biochem Behav , vol.87 , pp. 115-121
    • Haleem, D.J.1    Samad, N.2    Haleem, M.A.3
  • 36
    • 0036289385 scopus 로고    scopus 로고
    • Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs
    • 10.1016/S0893-133X(02)00287-7
    • Andersson C, Hamer RM, Lawler CP, Mailman RB, Lieberman JA. Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs. Neuropsychopharmacology. 2002; 27: 143-51. doi:10.1016/S0893-133X(02)00287-7
    • (2002) Neuropsychopharmacology , vol.27 , pp. 143-51
    • Andersson, C.1    Hamer, R.M.2    Lawler, C.P.3    Mailman, R.B.4    Lieberman, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.