Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers

International Journal of Molecular Epidemiology and Genetics

Volumn 1, Issue 2, 2010, Pages 114-123

  Inoue Choi, Maki ^a   Yuan, Jian Min ^a,b   Yang, Chung S ^c   van den Berg, David J ^d   Lee, Mao Jung ^c   Gao, Yu Tang ^e   Yu, Mimi C ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e SHANGHAI CANCER INSTITUTE   (China)

Author keywords

COMT genotype; Green tea; Urinary tea polyphenols

Indexed keywords

CATECHOL METHYLTRANSFERASE; CREATININE; POLYPHENOL;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE URINE LEVEL; DIET; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOTE; HUMAN; INTERVIEW; MALE; METABOLITE; NEOPLASM; PROSPECTIVE STUDY; TEA; URINALYSIS; URINE LEVEL; WILD TYPE;

ANIMALIA;

EID: 77954631104     PISSN: None     EISSN: 19481756     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Yang CS, Maliakal P and Meng X. Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 2002; 42: 25-54.
2. Wu AH, Yu MC, Tseng CC, Hankin J and Pike MC. Green tea and risk of breast cancer in Asian Americans. Int J Cancer 2003; 106: 574-579.
3. Sun CL, Yuan JM, Koh WP and Yu MC. Green tea, black tea and breast cancer risk: a metaanalysis of epidemiological studies. Carcinogenesis 2006; 27: 1310-1315.
4. Seely D, Mills EJ, Wu P, Verma S and Guyatt GH. The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review and meta-analysis. Integr Cancer Ther 2005; 4: 144-155.
5. Suzuki Y, Tsubono Y, Nakaya N, Koizumi Y and Tsuji I. Green tea and the risk of breast cancer: pooled analysis of two prospective studies in Japan. Br J Cancer 2004; 90: 1361-1363.
6. Nakachi K, Suemasu K, Suga K, Takeo T, Imai K and Higashi Y. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res 1998; 89: 254-261.
7. Zhu BT, Patel UK, Cai MX and Conney AH. OMethylation of tea polyphenols catalyzed by human placental cytosolic catechol-Omethyltransferase. Drug Metab Dispos 2000; 28: 1024-1030.
8. Meng X, Sang S, Zhu N, Lu H, Sheng S, Lee MJ, Ho CT and Yang CS. Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats. Chem Res Toxicol 2002; 15: 1042-1050.
9. Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL and Weinshilboum RM. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 1996; 6: 243-250.
10. Dawling S, Roodi N, Mernaugh RL, Wang X and Parl FF. Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms. Cancer Res 2001; 61: 6716-6722.
11. Weinshilboum RM, Otterness DM and Szumlanski CL. Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase. Annu Rev Pharmacol Toxicol 1999; 39: 19-52.
12. Wu AH, Tseng CC, Van Den Berg D and Yu MC. Tea intake, COMT genotype, and breast cancer in Asian-American women. Cancer Res 2003; 63: 7526-7529.
13. Ross RK, Yuan JM, Yu MC, Wogan GN, Qian GS, Tu JT, Groopman JD, Gao YT and Henderson BE. Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet 1992; 339: 943-946.
14. Yuan JM, Ross RK, Wang XL, Gao YT, Henderson BE and Yu MC. Morbidity and mortality in relation to cigarette smoking in Shanghai, China. A prospective male cohort study. JAMA 1996; 275: 1646-1650.
15. Ross RK, Yuan JM, Henderson BE, Park J, Gao YT and Yu MC. Prospective evaluation of dietary and other predictors of fatal stroke in Shanghai, China. Circulation 1997; 96: 50-55.
16. Yuan JM, Gao YT, Yang CS and Yu MC. Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study. Int J Cancer 2007; 120: 1344-1350.
17. Yuan JM, Lu SC, Van Den Berg D, Govindarajan S, Zhang ZQ, Mato JM and Yu MC. Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma. Hepatology 2007; 46: 749-758.
18. Li C, Lee MJ, Sheng S, Meng X, Prabhu S, Winnik B, Huang B, Chung JY, Yan S, Ho CT and Yang CS. Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion. Chem Res Toxicol 2000; 13: 177-184.
19. Lee MJ, Prabhu S, Meng X, Li C and Yang CS. An improved method for the determination of green and black tea polyphenols in biomatrices by high -performance liquid chromatography with coulometric array detection. Anal Biochem 2000; 279: 164-169.
20. Slot C. Plasma creatinine determination. A new and specific Jaffe reaction method. Scand J Clin Lab Invest 1965; 17: 381-387.
21. Seow A, Yuan JM, Sun CL, Van Den Berg D, Lee HP and Yu MC. Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis 2002; 23: 2055-2061.
22. Gago-Dominguez M, Castelao JE, Sun CL, Van Den Berg D, Koh WP, Lee HP and Yu MC. Marine n-3 fatty acid intake, glutathione S-transferase polymorphisms and breast cancer risk in postmenopausal Chinese women in Singapore. Carcinogenesis 2004; 25: 2143-2147.
23. Lavigne JA, Helzlsouer KJ, Huang HY, Strickland PT, Bell DA, Selmin O, Watson MA, Hoffman S, Comstock GW and Yager JD. An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer. Cancer Res 1997; 57: 5493-5497.
24. Lee LG, Connell CR and Bloch W. Allelic discrimination by nick-translation PCR with fluorogenic probes. Nucleic Acids Res 1993; 21: 3761-3766.
25. Shrubsole MJ, Lu W, Chen Z, Shu XO, Zheng Y, Dai Q, Cai Q, Gu K, Ruan ZX, Gao YT and Zheng W. Drinking green tea modestly reduces breast cancer risk. J Nutr 2009; 139: 310-316.
26. Lambert JD, Sang S and Yang CS. Biotransformation of green tea polyphenols and the biological activities of those metabolites. Mol Pharm 2007; 4: 819-825.
27. Yassin MS, Cheng H, Ekblom J and Oreland L. Inhibitors of catecholamine metabolizing enzymes cause changes in S-adenosylmethionine and S-adenosylhomocysteine in the rat brain. Neurochem Int 1998; 32: 53-59.
28. Waldmeier PC and Feldtrauer JJ. On the role of O -methylation in the metabolism of Sadenosylmethionine in rat brain. Biochem Pharmacol 1987; 36: 2855-2861.
29. Yang CS, Chen L, Lee MJ, Balentine D, Kuo MC and Schantz SP. Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers. Cancer Epidemiol Biomarkers Prev 1998; 7: 351-354.
30. Li C, Meng X, Winnik B, Lee MJ, Lu H, Sheng S, Buckley B and Yang CS. Analysis of urinary metabolites of tea catechins by liquid chromatography/ electrospray ionization mass spectrometry. Chem Res Toxicol 2001; 14: 702-707.
31. Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, Lambert G, Mohr S and Yang CS. Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers Prev 2002; 11: 1025-1032.
32. Lee MJ, Wang ZY, Li H, Chen L, Sun Y, Gobbo S, Balentine DA and Yang CS. Analysis of plasma and urinary tea polyphenols in human subjects. Cancer Epidemiol Biomarkers Prev 1995; 4: 393-399.