Internalization of the human nicotinic acid receptor GPR109A is regulated by Gi, GRK2, and arrestin3

Journal of Biological Chemistry

Volumn 285, Issue 29, 2010, Pages 22605-22618

  Li, Guo ^a   Shi, Ying ^a   Huang, Haishan ^a   Zhang, Yaping ^a   Wu, Kuangpei ^b   Luo, Jiansong ^c   Sun, Yi ^a   Lu, Jianxin ^b   Benovic, Jeffrey L ^c   Zhou, Naiming ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CARBOXYL-TERMINAL; CELL SURFACES; CLATHRINS; COUPLED RECEPTORS; ENHANCED GREEN FLUORESCENT PROTEIN; FORSKOLIN; FREE FATTY ACID; G PROTEIN COUPLED RECEPTORS; G PROTEIN-COUPLED RECEPTOR KINASE 2; HEK293 CELLS; INTRACELLULAR CA; MOLECULAR MECHANISM; MONENSIN; NICOTINIC ACID; PERTUSSIS TOXIN; PLASMA MEMBRANES; PRE-TREATMENT; RECEPTOR RECYCLING; RNA INTERFERENCE; TIME-DEPENDENT;

ACIDS; CALCIUM; CELL MEMBRANES; FATTY ACIDS; FETAL MONITORING; PYRIDINE; RECYCLING; RNA; SUGAR (SUCROSE);

PROTEINS;

CLATHRIN; CYCLIC AMP; ENHANCED GREEN FLUORESCENT PROTEIN; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 109A; G PROTEIN COUPLED RECEPTOR KINASE 2; MONENSIN; PERTUSSIS TOXIN; RETINA S ANTIGEN; RNA; SUCROSE; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; INTERNALIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; ARRESTINS; CELL LINE; CLATHRIN; COATED PITS, CELL-MEMBRANE; DYNAMINS; ENDOCYTOSIS; ENDOSOMES; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; LYSOSOMES; MODELS, BIOLOGICAL; PERTUSSIS TOXIN; PROTEIN TRANSPORT; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; RECOMBINANT FUSION PROTEINS; SRC-FAMILY KINASES;

EID: 77954608826     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.087213     Document Type: Article

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