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Volumn 12, Issue 6, 2010, Pages 501-515

Adjusting transgene expression levels in lymphocytes with a set of inducible promoters

Author keywords

Cell death; Doxycycline; Gene regulation; Inducible expression; Lymphocytes; Reporter genes

Indexed keywords

CASPASE 3; CD123 ANTIGEN; ENHANCED GREEN FLUORESCENT PROTEIN; TETRACYCLINE; HYBRID PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 77954606202     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1461     Document Type: Article
Times cited : (24)

References (53)
  • 1
    • 0042268512 scopus 로고    scopus 로고
    • Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes
    • Berens C, Hillen W. Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes. Eur J Biochem2003; 270: 3109-3121.
    • (2003) Eur J Biochem , vol.270 , pp. 3109-3121
    • Berens, C.1    Hillen, W.2
  • 2
    • 6344226516 scopus 로고    scopus 로고
    • Tetracycline derivatives: Alternative effectors for Tet transregulators
    • Krueger C, Pfleiderer K, Hillen W, et al. Tetracycline derivatives: alternative effectors for Tet transregulators. BioTechniques 2004; 37: 546-550. (Pubitemid 39391168)
    • (2004) BioTechniques , vol.37 , Issue.4 , pp. 546-550
    • Krueger, C.1    Pfleiderer, K.2    Hillen, W.3    Berens, C.4
  • 3
    • 0030681310 scopus 로고    scopus 로고
    • Inducible gene expression in mammalian cells and transgenic mice
    • Saez E, No D, West A, et al. Inducible gene expression in mammalian cells and transgenic mice. Curr Opin Biotechnol 1997; 8: 608-616.
    • (1997) Curr Opin Biotechnol , vol.8 , pp. 608-616
    • Saez, E.1    No, D.2    West, A.3
  • 4
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992; 89: 5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 5
    • 0028795108 scopus 로고
    • Efficacy of tetracycline-controlled gene expression is influenced by cell type
    • Ackland-Berglund CE, Leib DA. Efficacy of tetracycline-controlled gene expression is influenced by cell type. BioTechniques 1995; 18: 196-200.
    • (1995) BioTechniques , vol.18 , pp. 196-200
    • Ackland-Berglund, C.E.1    Leib, D.A.2
  • 6
    • 0029009922 scopus 로고
    • The responsiveness of a tetracycline-sensitive expression system differs in different cell lines
    • Howe JR, Skryabin BV, Belcher SM, et al. The responsiveness of a tetracycline-sensitive expression system differs in different cell lines. J Biol Chem 1995; 270: 14168-14174.
    • (1995) J Biol Chem , vol.270 , pp. 14168-14174
    • Howe, J.R.1    Skryabin, B.V.2    Belcher, S.M.3
  • 7
    • 30344473326 scopus 로고    scopus 로고
    • Efficient control of gene expression in the hematopoietic system using a single Tet-on inducible lentiviral vector
    • Barde I, Zanta-Boussif MA, Paisant S, et al. Efficient control of gene expression in the hematopoietic system using a single Tet-on inducible lentiviral vector. Mol Ther 2006; 13: 382-390.
    • (2006) Mol Ther , vol.13 , pp. 382-390
    • Barde, I.1    Zanta-Boussif, M.A.2    Paisant, S.3
  • 8
    • 33747863329 scopus 로고    scopus 로고
    • A gene regulation system with four distinct expression levels
    • Krueger C, Danke C, Pfleiderer K, et al. A gene regulation system with four distinct expression levels. J Gene Med 2006; 8: 1037-1047.
    • (2006) J Gene Med , vol.8 , pp. 1037-1047
    • Krueger, C.1    Danke, C.2    Pfleiderer, K.3
  • 9
    • 0034159971 scopus 로고    scopus 로고
    • The tetracycline-responsive promoter contains functional interferon-inducible response elements
    • Rang A, Will H. The tetracycline-responsive promoter contains functional interferon-inducible response elements. Nucleic Acids Res 2000; 28: 1120-1125. (Pubitemid 30107680)
    • (2000) Nucleic Acids Research , vol.28 , Issue.5 , pp. 1120-1125
    • Rang, A.1    Will, H.2
  • 10
    • 25144502434 scopus 로고    scopus 로고
    • An optimized conditional suicide switch using doxycycline-dependent expression of human tBid
    • Knott A, Drueppel L, Beyer T, et al. An optimized conditional suicide switch using doxycycline-dependent expression of human tBid. Cancer Biol Ther 2005; 4: 532-536.
    • (2005) Cancer Biol Ther , vol.4 , pp. 532-536
    • Knott, A.1    Drueppel, L.2    Beyer, T.3
  • 11
    • 0033761127 scopus 로고    scopus 로고
    • Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema
    • Zheng T, Zhu Z, Wang Z, et al. Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest 2000; 106: 1081-1093.
    • (2000) J Clin Invest , vol.106 , pp. 1081-1093
    • Zheng, T.1    Zhu, Z.2    Wang, Z.3
  • 12
    • 43249097209 scopus 로고    scopus 로고
    • Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis
    • Sleat DE, El-Banna M, Sohar I, et al. Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis. Mol Genet Metab 2008; 94: 222-233.
    • (2008) Mol Genet Metab , vol.94 , pp. 222-233
    • Sleat, D.E.1    El-Banna, M.2    Sohar, I.3
  • 13
    • 0031740332 scopus 로고    scopus 로고
    • Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16
    • Rossi FMV, Guicherit OM, Spicher A, et al. Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16. Nat Genet 1998; 20: 389-393.
    • (1998) Nat Genet , vol.20 , pp. 389-393
    • Rossi, F.M.V.1    Guicherit, O.M.2    Spicher, A.3
  • 14
    • 0033555764 scopus 로고    scopus 로고
    • Tetracycline-inducible expression systems with reduced basal activity in mammalian cells
    • Forster K, Helbl V, Lederer T, et al. Tetracycline-inducible expression systems with reduced basal activity in mammalian cells. Nucleic Acids Res 1999; 27: 708-710.
    • (1999) Nucleic Acids Res , vol.27 , pp. 708-710
    • Forster, K.1    Helbl, V.2    Lederer, T.3
  • 15
    • 0032600013 scopus 로고    scopus 로고
    • A Tetracycline Controlled Activation/Repression System with Increased Potential for Gene Transfer into Mammalian Cells
    • Freundlieb S, Schirra-M̈uller C, Bujard H. A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells. J Gene Med 1999; 1: 4-12. (Pubitemid 129631058)
    • (1999) Journal of Gene Medicine , vol.1 , Issue.1 , pp. 4-12
    • Freundlieb, S.1    Schirra-Muller, C.2    Bujard, H.3
  • 16
    • 85069129788 scopus 로고    scopus 로고
    • Clontech pTRE-Tight vectors
    • Clontech: Palo Alto, CA
    • Clontech pTRE-Tight vectors. Clontechniques. Clontech: Palo Alto, CA, 2003.
    • (2003) Clontechniques
  • 17
    • 13644264181 scopus 로고    scopus 로고
    • Second-generation tetracycline-regulatable promoter: Repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness
    • Agha-Mohammadi S, O'Malley M, Etemad A, et al. Second-generation tetracycline-regulatable promoter: repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness. J Gene Med 2004; 6: 817-828.
    • (2004) J Gene Med , vol.6 , pp. 817-828
    • Agha-Mohammadi, S.1    O'Malley, M.2    Etemad, A.3
  • 18
    • 0035932984 scopus 로고    scopus 로고
    • In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
    • Marzio G, Verhoef K, Vink M, et al. In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies. Proc Natl Acad Sci USA 2001; 98: 6342-6347.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6342-6347
    • Marzio, G.1    Verhoef, K.2    Vink, M.3
  • 19
    • 0030835644 scopus 로고    scopus 로고
    • A novel tetracycline-dependent expression vector with low basal expression and potent regulatory properties in various mammalian cell lines
    • Hoffmann A, Villalba M, Journot L, et al. A novel tetracycline-dependent expression vector with low basal expression and potent regulatory properties in various mammalian cell lines. Nucleic Acids Res 1997; 25: 1078-1079.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1078-1079
    • Hoffmann, A.1    Villalba, M.2    Journot, L.3
  • 20
    • 5644287672 scopus 로고    scopus 로고
    • Tetracycline-inducible expression systems for the generation of transgenic animals: A comparison of various inducible systems carried in a single vector
    • Backman CM, Zhang Y, Hoffer BJ, et al. Tetracycline-inducible expression systems for the generation of transgenic animals: a comparison of various inducible systems carried in a single vector. J Neurosci Methods 2004; 139: 257-262.
    • (2004) J Neurosci Methods , vol.139 , pp. 257-262
    • Backman, C.M.1    Zhang, Y.2    Hoffer, B.J.3
  • 21
    • 21044449615 scopus 로고    scopus 로고
    • Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters
    • Pluta K, Luce MJ, Bao L, et al. Tight control of transgene expression by lentivirus vectors containing second-generation tetracycline-responsive promoters. J Gene Med 2005; 7: 803-817.
    • (2005) J Gene Med , vol.7 , pp. 803-817
    • Pluta, K.1    Luce, M.J.2    Bao, L.3
  • 22
    • 61349179407 scopus 로고    scopus 로고
    • Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling
    • Herzog S, Reth M, Jumaa H. Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nat Rev Immunol 2009; 9: 195-205.
    • (2009) Nat Rev Immunol , vol.9 , pp. 195-205
    • Herzog, S.1    Reth, M.2    Jumaa, H.3
  • 23
    • 61849128182 scopus 로고    scopus 로고
    • T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
    • Salmond RJ, Filby A, Qureshi I, et al. T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol Rev 2009; 228: 9-22.
    • (2009) Immunol Rev , vol.228 , pp. 9-22
    • Salmond, R.J.1    Filby, A.2    Qureshi, I.3
  • 24
    • 38649090061 scopus 로고    scopus 로고
    • Immunological decision-making: How does the immune system decide to mount a helper T-cell response?
    • Kaiko GE, Horvat JC, Beagley KW, et al. Immunological decision-making: how does the immune system decide to mount a helper T-cell response? Immunology 2008; 123: 326-338.
    • (2008) Immunology , vol.123 , pp. 326-338
    • Kaiko, G.E.1    Horvat, J.C.2    Beagley, K.W.3
  • 25
    • 58149097584 scopus 로고    scopus 로고
    • The who, how and where of antigen presentation to B cells
    • Batista FD, Harwood NE. The who, how and where of antigen presentation to B cells. Nat Rev Immunol 2009; 9: 15-27.
    • (2009) Nat Rev Immunol , vol.9 , pp. 15-27
    • Batista, F.D.1    Harwood, N.E.2
  • 26
    • 0029993331 scopus 로고    scopus 로고
    • Apoptosis and the maintenance of homoeostasis in the immune system
    • DOI 10.1016/S0952-7915(96)80063-X
    • Osborne BA. Apoptosis and the maintenance of homoeostasis in the immune system. Curr Opin Immunol 1996; 8: 245-254. (Pubitemid 26166990)
    • (1996) Current Opinion in Immunology , vol.8 , Issue.2 , pp. 245-254
    • Osborne, B.A.1
  • 27
    • 56749180605 scopus 로고    scopus 로고
    • Immunotherapy of autoimmunity and cancer: The penalty for success
    • Caspi RR. Immunotherapy of autoimmunity and cancer: the penalty for success. Nat Rev Immunol 2008; 8: 970-976.
    • (2008) Nat Rev Immunol , vol.8 , pp. 970-976
    • Caspi, R.R.1
  • 28
    • 34250718593 scopus 로고    scopus 로고
    • The suicide gene therapy challenge: How to improve a successful gene therapy approach
    • Bonini C, Bondanza A, Perna SK, et al. The suicide gene therapy challenge: how to improve a successful gene therapy approach. Mol Ther 2007; 15: 1248-1252.
    • (2007) Mol Ther , vol.15 , pp. 1248-1252
    • Bonini, C.1    Bondanza, A.2    Perna, S.K.3
  • 29
    • 44449114273 scopus 로고    scopus 로고
    • An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease
    • de Witte MA, Jorritsma A, Swart E, et al. An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease. J Immunol 2008; 180: 6365-6373.
    • (2008) J Immunol , vol.180 , pp. 6365-6373
    • De Witte, M.A.1    Jorritsma, A.2    Swart, E.3
  • 30
    • 62949195751 scopus 로고    scopus 로고
    • Genetic control of wayward pluripotent stem cells and their progeny after transplantation
    • KiuruM, BoyerJL, O'ConnorTP, et al. Genetic control of wayward pluripotent stem cells and their progeny after transplantation. Cell Stem Cell 2009; 4: 289-300.
    • (2009) Cell Stem Cell , vol.4 , pp. 289-300
    • Kiuru, M.1    Boyer, J.L.2    O'Connor, T.P.3
  • 31
    • 34548649502 scopus 로고    scopus 로고
    • Ig heavy chain promotes mature B cell survival in the absence of light chain
    • Geraldes P, Rebrovich M, Herrmann K, et al. Ig heavy chain promotes mature B cell survival in the absence of light chain. J Immunol 2007; 179: 1659-1668.
    • (2007) J Immunol , vol.179 , pp. 1659-1668
    • Geraldes, P.1    Rebrovich, M.2    Herrmann, K.3
  • 32
    • 34547699018 scopus 로고    scopus 로고
    • Inducible gene expression with the Tet-on system in CD4+ T cells and thymocytes of mice
    • Huai J, Firat E, Niedermann G. Inducible gene expression with the Tet-on system in CD4+ T cells and thymocytes of mice. Genesis 2007; 45: 427-431.
    • (2007) Genesis , vol.45 , pp. 427-431
    • Huai, J.1    Firat, E.2    Niedermann, G.3
  • 33
    • 41949098160 scopus 로고    scopus 로고
    • Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
    • Hanna J, Markoulaki S, Schorderet P, et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 2008; 133: 250-264.
    • (2008) Cell , vol.133 , pp. 250-264
    • Hanna, J.1    Markoulaki, S.2    Schorderet, P.3
  • 34
    • 0019846013 scopus 로고
    • Organization and reorganization of immunoglobulin genes in A-MULV-transformed cells: Rearrangement of heavy but not light chain genes
    • Alt F, Rosenberg N, Lewis S, et al. Organization and reorganization of immunoglobulin genes in A-MULV-transformed cells: rearrangement of heavy but not light chain genes. Cell 1981; 27: 381-390.
    • (1981) Cell , vol.27 , pp. 381-390
    • Alt, F.1    Rosenberg, N.2    Lewis, S.3
  • 35
    • 0019516872 scopus 로고
    • Cell cycle related heterogeneity of Ia antigen expression on a murine B lymphoma cell line: Analysis by flow cytometry
    • Lanier LL, Warner NL. Cell cycle related heterogeneity of Ia antigen expression on a murine B lymphoma cell line: analysis by flow cytometry. J Immunol 1981; 126: 626-631.
    • (1981) J Immunol , vol.126 , pp. 626-631
    • Lanier, L.L.1    Warner, N.L.2
  • 36
    • 0018726056 scopus 로고
    • A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines
    • Kearney JF, Radbruch A, Liesegang B, et al. A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J Immunol 1979; 123: 1548-1550.
    • (1979) J Immunol , vol.123 , pp. 1548-1550
    • Kearney, J.F.1    Radbruch, A.2    Liesegang, B.3
  • 37
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
    • Urlinger S, Baron U, Thellmann M, et al. Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc Natl Acad Sci USA 2000; 97: 7963-7968.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3
  • 38
    • 0037145513 scopus 로고    scopus 로고
    • A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture
    • Anastassiadis K, Kim J, Daigle N, et al. A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture. Gene 2002; 298: 159-172.
    • (2002) Gene , vol.298 , pp. 159-172
    • Anastassiadis, K.1    Kim, J.2    Daigle, N.3
  • 39
    • 0442307865 scopus 로고    scopus 로고
    • Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors
    • Qu Z, Thottassery JV, Van Ginkel S, et al. Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors. Gene 2004; 327: 61-73.
    • (2004) Gene , vol.327 , pp. 61-73
    • Qu, Z.1    Thottassery, J.V.2    Van Ginkel, S.3
  • 40
    • 0035662980 scopus 로고    scopus 로고
    • Interleukin-3 receptor á chain (CD123) is widely expressed in hematologic malignancies
    • Munoz L, Nomdedeu JF, Lopez O, et al. Interleukin-3 receptor á chain (CD123) is widely expressed in hematologic malignancies. Haematologica 2001; 86: 1261-1269.
    • (2001) Haematologica , vol.86 , pp. 1261-1269
    • Munoz, L.1    Nomdedeu, J.F.2    Lopez, O.3
  • 41
    • 0037108559 scopus 로고    scopus 로고
    • Elevated expression of IL-3Rα in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis
    • Testa U, Riccioni R, Militi S, et al. Elevated expression of IL-3Rα in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis. Blood 2002; 100: 2980-2988.
    • (2002) Blood , vol.100 , pp. 2980-2988
    • Testa, U.1    Riccioni, R.2    Militi, S.3
  • 42
    • 0033893119 scopus 로고    scopus 로고
    • In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein
    • Alexander RL, Kucera GL, Klein B, et al. In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein. Bioconjug Chem 2000; 11: 564-568.
    • (2000) Bioconjug Chem , vol.11 , pp. 564-568
    • Alexander, R.L.1    Kucera, G.L.2    Klein, B.3
  • 43
    • 34547729633 scopus 로고    scopus 로고
    • New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells
    • Du X, Ho M, Pastan I. New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells. J Immunother 2007; 30: 607-613.
    • (2007) J Immunother , vol.30 , pp. 607-613
    • Du, X.1    Ho, M.2    Pastan, I.3
  • 44
    • 0034886842 scopus 로고    scopus 로고
    • High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein
    • Alexander RL, Ramage J, Kucera GL, et al. High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein. Leuk Res 2001; 25: 875-881.
    • (2001) Leuk Res , vol.25 , pp. 875-881
    • Alexander, R.L.1    Ramage, J.2    Kucera, G.L.3
  • 45
    • 16944367543 scopus 로고    scopus 로고
    • Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLLAF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23)
    • Matsuo Y, MacLeod RA, Uphoff CC, et al. Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLLAF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23). Leukemia 1997; 11: 1469-1477.
    • (1997) Leukemia , vol.11 , pp. 1469-1477
    • Matsuo, Y.1    MacLeod, R.A.2    Uphoff, C.C.3
  • 46
    • 0032562661 scopus 로고    scopus 로고
    • Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits
    • Srinivasula SM, Ahmad M, MacFarlane M, et al. Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits. J Biol Chem 1998; 273: 10107-10111.
    • (1998) J Biol Chem , vol.273 , pp. 10107-10111
    • Srinivasula, S.M.1    Ahmad, M.2    MacFarlane, M.3
  • 47
    • 0035902601 scopus 로고    scopus 로고
    • Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death
    • Suzuki Y, Nakabayashi Y, Takahashi R. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc Natl Acad Sci USA 2001; 98: 8662-8667.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8662-8667
    • Suzuki, Y.1    Nakabayashi, Y.2    Takahashi, R.3
  • 50
    • 0035881310 scopus 로고    scopus 로고
    • Cell growth inhibition by the multifunctional multivalent zinc-finger factor CTCF
    • Rasko JE, Klenova EM, Leon J, et al. Cell growth inhibition by the multifunctional multivalent zinc-finger factor CTCF. Cancer Res 2001; 61: 6002-6007.
    • (2001) Cancer Res , vol.61 , pp. 6002-6007
    • Rasko, J.E.1    Klenova, E.M.2    Leon, J.3
  • 51
    • 33748353422 scopus 로고    scopus 로고
    • A retroviral expression system based on tetracycline-regulated tricistronic transactivator/repressor vectors for functional analyses of antiproliferative and toxic genes
    • Ausserlechner MJ, Obexer P, Deutschmann A, et al. A retroviral expression system based on tetracycline-regulated tricistronic transactivator/repressor vectors for functional analyses of antiproliferative and toxic genes. Mol Cancer Ther 2006; 5: 1927-34.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1927-1934
    • Ausserlechner, M.J.1    Obexer, P.2    Deutschmann, A.3
  • 52
    • 0037085927 scopus 로고    scopus 로고
    • A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors
    • Feuring-Buske M, Frankel AE, Alexander RL, et al. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors. Cancer Res 2002; 62: 1730-1736. (Pubitemid 34408495)
    • (2002) Cancer Research , vol.62 , Issue.6 , pp. 1730-1736
    • Feuring-Buske, M.1    Frankel, A.E.2    Alexander, R.L.3    Gerhard, B.4    Hogge, D.E.5
  • 53
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, Zhang X, Parsons DW, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008; 321: 1801-1806.
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3


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