메뉴 건너뛰기




Volumn 224, Issue 3, 2010, Pages 722-733

N-terminal interaction domain implicates PAK4 in translational regulation and reveals novel cellular localization signals

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; P21 ACTIVATED KINASE 4; PROTEIN CDC42; RIBONUCLEOPROTEIN;

EID: 77954605404     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22172     Document Type: Article
Times cited : (19)

References (52)
  • 1
    • 0032538973 scopus 로고    scopus 로고
    • PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
    • Abo A, Qu J, Cammarano MS, Dan C, Fritsch A, Baud V, Belisle B, Minden A. 1998. PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia. EMBO 17:6527-6540. (Pubitemid 28521788)
    • (1998) EMBO Journal , vol.17 , Issue.22 , pp. 6527-6540
    • Abo, A.1    Qu, J.2    Cammarano, M.S.3    Dan, C.4    Fritsch, A.5    Baud, V.6    Belisle, B.7    Minden, A.8
  • 2
    • 43049167377 scopus 로고    scopus 로고
    • A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF
    • Ahmed T, Shea K, Masters JR, Jones GE, Wells CM. 2008. A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF. Cell Signal 20:1320-1328.
    • (2008) Cell Signal , vol.20 , pp. 1320-1328
    • Ahmed, T.1    Shea, K.2    Masters, J.R.3    Jones, G.E.4    Wells, C.M.5
  • 4
    • 0029686290 scopus 로고    scopus 로고
    • The large ribosomal subunit stalk as a regulatory element of the eukaryotic translational machinery
    • Ballesta JP, Remacha M. 1996. The large ribosomal subunit stalk as a regulatory element of the eukaryotic translational machinery. Prog Nucleic Acid Res Mol Biol 55:157-193.
    • (1996) Prog Nucleic Acid Res Mol Biol , vol.55 , pp. 157-193
    • Ballesta, J.P.1    Remacha, M.2
  • 5
    • 70349591634 scopus 로고    scopus 로고
    • Identification of PAK4 as a putative target gene for amplification within 19q13.12-q13.2 in oral squamouscell carcinoma
    • Begum A, Imoto I, Kozaki K, Tsuda H, Suzuki E, Amagasa T, Inazawa J. 2009. Identification of PAK4 as a putative target gene for amplification within 19q13.12-q13.2 in oral squamouscell carcinoma. Cancer Sci 100:1908-1916.
    • (2009) Cancer Sci , vol.100 , pp. 1908-1916
    • Begum, A.1    Imoto, I.2    Kozaki, K.3    Tsuda, H.4    Suzuki, E.5    Amagasa, T.6    Inazawa, J.7
  • 6
    • 0027205394 scopus 로고
    • The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation
    • Borman A, Howell MT, Patton JG, Jackson RJ. 1993. The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation. J Gen Virol 74:1775-1788. (Pubitemid 23272342)
    • (1993) Journal of General Virology , vol.74 , Issue.9 , pp. 1775-1788
    • Borman, A.1    Howell, M.T.2    Patton, J.G.3    Jackson, R.J.4
  • 8
    • 37049030005 scopus 로고    scopus 로고
    • Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs
    • DOI 10.1091/mbc.E07-06-0603
    • Cammas A, Pileur F, Bonnal S, Lewis SM, Lévêque N, Holcik M, Vagner S. 2007. Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs. Mol Biol Cell 18:5048-5059. (Pubitemid 350246704)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.12 , pp. 5048-5059
    • Cammas, A.1    Pileur, F.2    Bonnal, S.3    Lewis, S.M.4    Leveque, N.5    Holcik, M.6    Vagner, S.7
  • 10
    • 0141817910 scopus 로고    scopus 로고
    • Identification of an Autoinhibitory Domain of p21-activated Protein Kinase 5
    • DOI 10.1074/jbc.C300234200
    • Ching YP, Leong VY, Wong CM, Kung HF. 2003. Identification of an autoinhibitory domain of p21-activated protein kinase 5. J Biol Chem 278:33621-33624. (Pubitemid 37553193)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.36 , pp. 33621-33624
    • Ching, Y.-P.1    Leong, V.Y.L.2    Wong, C.-M.3    Kung, H.-F.4
  • 12
    • 33645815687 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
    • Cotteret S, Chernoff J. 2006. Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties. Mol Cell Biol 26:3215-3230.
    • (2006) Mol Cell Biol , vol.26 , pp. 3215-3230
    • Cotteret, S.1    Chernoff, J.2
  • 15
    • 0142123165 scopus 로고    scopus 로고
    • Death Receptor-Induced Activation of Initiator Caspase 8 Is Antagonized by Serine/Threonine Kinase PAK4
    • DOI 10.1128/MCB.23.21.7838-7848.2003
    • Gnesutta N, Minden A. 2003. Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4. Mol Cell Biol 23:7838-7848. (Pubitemid 37271480)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.21 , pp. 7838-7848
    • Gnesutta, N.1    Minden, A.2
  • 16
    • 0035957986 scopus 로고    scopus 로고
    • The Serine/Threonine Kinase PAK4 Prevents Caspase Activation and Protects Cells from Apoptosis
    • Gnesutta N, Qu J, Minden A. 2001. The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis. J Biol Chem 276:14414-14419. (Pubitemid 37391833)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.17 , pp. 14414-14419
    • Gnesutta, N.1    Qu, J.2    Minden, A.3
  • 17
    • 33749242977 scopus 로고    scopus 로고
    • PAK4 and alphaPIX determine podosome size and number in macrophages through localized actin regulation
    • DOI 10.1002/jcp.20777
    • Gringel A, Walz D, Rosenberger G, Minden A, Kutsche K, Kopp P, Linder S. 2006. PAK4 and alpha PIX determine podosome size and number in macrophages through localized actin regulation. J Cell Physiol 209:568-579. (Pubitemid 44484648)
    • (2006) Journal of Cellular Physiology , vol.209 , Issue.2 , pp. 568-579
    • Gringel, A.1    Walz, D.2    Rosenberger, G.3    Minden, A.4    Kutsche, K.5    Kopp, P.6    Linder, S.7
  • 19
    • 0035396727 scopus 로고    scopus 로고
    • Internal ribosome entry sites in eukaryotic mRNA molecules
    • DOI 10.1101/gad.891101
    • Hellen CU, Sarnow P. 2001. Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev 15:1593-1612. (Pubitemid 32702581)
    • (2001) Genes and Development , vol.15 , Issue.13 , pp. 1593-1612
    • Hellen, C.U.T.1    Sarnow, P.2
  • 20
    • 17144424622 scopus 로고    scopus 로고
    • Translational control in stress and apoptosis
    • Holcik M, Sonenberg N. 2005. Translational control in stress and apoptosis. Nat Rev Mol Cell Biol 6:318-327.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 318-327
    • Holcik, M.1    Sonenberg, N.2
  • 22
    • 0023758546 scopus 로고
    • A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
    • Jang SK, Kräusslich HG, Nicklin MJ, Duke GM, Palmenberg AC, Wimmer E. 1988. A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J Virol 62:2636-2643.
    • (1988) J Virol , vol.62 , pp. 2636-2643
    • Jang, S.K.1    Kräusslich, H.G.2    Nicklin, M.J.3    Duke, G.M.4    Palmenberg, A.C.5    Wimmer, E.6
  • 23
    • 33144472700 scopus 로고    scopus 로고
    • Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex
    • Jao DL, Chen KY. 2006. Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex. J Cell Biochem 97:583-598.
    • (2006) J Cell Biochem , vol.97 , pp. 583-598
    • Jao, D.L.1    Chen, K.Y.2
  • 26
    • 55549107531 scopus 로고    scopus 로고
    • The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control
    • Lai MC, Lee YH, Tarn WY. 2008. The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control. Mol Biol Cell 19:3847-3858.
    • (2008) Mol Biol Cell , vol.19 , pp. 3847-3858
    • Lai, M.C.1    Lee, Y.H.2    Tarn, W.Y.3
  • 27
    • 39149111540 scopus 로고    scopus 로고
    • For IRES trans-acting factors, it is all about location
    • DOI 10.1038/sj.onc.1210777, PII 1210777
    • Lewis SM, Holcik M. 2008. For IRES trans-acting factors, it is all about location. Oncogene 27:1033-1035. (Pubitemid 351253194)
    • (2008) Oncogene , vol.27 , Issue.8 , pp. 1033-1035
    • Lewis, S.M.1    Holcik, M.2
  • 28
    • 29244439927 scopus 로고    scopus 로고
    • PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor
    • DOI 10.1074/jbc.M506884200
    • Li X, Minden A. 2005. PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor. J Biol Chem 280:41192-41200. (Pubitemid 41832173)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.50 , pp. 41192-41200
    • Li, X.1    Minden, A.2
  • 29
    • 28644439239 scopus 로고    scopus 로고
    • Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2
    • DOI 10.1038/sj.emboj.7600868
    • Ling J, Morley SJ, Traugh JA. 2005. Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2. EMBO J 24:4094-4105. (Pubitemid 41752878)
    • (2005) EMBO Journal , vol.24 , Issue.23 , pp. 4094-4105
    • Ling, J.1    Morley, S.J.2    Traugh, J.A.3
  • 32
    • 0037855772 scopus 로고    scopus 로고
    • P21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death
    • DOI 10.1074/jbc.M205875200
    • Lu Y, Pan ZZ, Devaux Y, Ray P. 2003. p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death. J Biol Chem 278:10374-10380. (Pubitemid 36800301)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.12 , pp. 10374-10380
    • Lu, Y.1    Pan, Z.-Z.2    Devaux, Y.3    Ray, P.4
  • 33
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • DOI 10.1038/367040a0
    • Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L. 1994. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367:40-46. (Pubitemid 24038530)
    • (1994) Nature , vol.367 , Issue.6458 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.-S.4    Lim, L.5
  • 34
    • 49649113339 scopus 로고    scopus 로고
    • Internal translation initiation on the foot-and-mouth disease virus IRES is affected by ribosomal stalk conformation
    • Martínez-Azorín F, Remacha M, Martínez-Salas E, Ballesta JP. 2008. Internal translation initiation on the foot-and-mouth disease virus IRES is affected by ribosomal stalk conformation. FEBS Lett 582:3029-3032.
    • (2008) FEBS Lett , vol.582 , pp. 3029-3032
    • Martínez-Azorín, F.1    Remacha, M.2    Martínez-Salas, E.3    Ballesta, J.P.4
  • 36
    • 0027197508 scopus 로고
    • A Jun-binding protein related to a putative tumor suppressor
    • Monteclaro FS, Vogt PK. 1993. A Jun-binding protein related to a putative tumor suppressor. Proc Natl Acad Sci USA 90:6726-6730.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6726-6730
    • Monteclaro, F.S.1    Vogt, P.K.2
  • 37
    • 24644502657 scopus 로고    scopus 로고
    • From birth to death: The complex lives of eukaryotic mRNAs
    • Moore MJ. 2005. From birth to death: The complex lives of eukaryotic mRNAs. Science 309:1514-1518.
    • (2005) Science , vol.309 , pp. 1514-1518
    • Moore, M.J.1
  • 41
    • 49349112872 scopus 로고    scopus 로고
    • Polypyrimidine-tract-binding protein: A multifunctional RNA-binding protein
    • Sawicka K, Bushell M, Spriggs KA, Willis AE. 2008. Polypyrimidine-tract- binding protein: A multifunctional RNA-binding protein. Biochem Soc Trans 36:641-647.
    • (2008) Biochem Soc Trans , vol.36 , pp. 641-647
    • Sawicka, K.1    Bushell, M.2    Spriggs, K.A.3    Willis, A.E.4
  • 42
    • 20044389169 scopus 로고    scopus 로고
    • Internal ribosome entry segment-mediated translation during apoptosis: The role of IRES-trans-acting factors
    • DOI 10.1038/sj.cdd.4401642
    • Spriggs KA, Bushell M, Mitchell SA, Willis AE. 2005. Internal ribosome entry segment-mediated translation during apoptosis: The role of IRES-trans-acting factors. Cell Death Differ 12:585-591. (Pubitemid 40767161)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.6 , pp. 585-591
    • Spriggs, K.A.1    Bushell, M.2    Mitchell, S.A.3    Willis, A.E.4
  • 46
    • 0037107548 scopus 로고    scopus 로고
    • PAK4 is activated via PI3K in HGF-stimulated epithelial cells
    • Wells CM, Abo A, Ridley AJ. 2002. PAK4 is activated via PI3K in HGF-stimulated epithelial cells. J Cell Sci 115:3947-3956.
    • (2002) J Cell Sci , vol.115 , pp. 3947-3956
    • Wells, C.M.1    Abo, A.2    Ridley, A.J.3
  • 47
    • 33750509850 scopus 로고    scopus 로고
    • Multiple Rho proteins regulate the subcellular targeting of PAK5
    • Wu X, Frost JA. 2006. Multiple Rho proteins regulate the subcellular targeting of PAK5. Biochem Biophys Res Commun 351:328-335.
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 328-335
    • Wu, X.1    Frost, J.A.2
  • 48
    • 0035805587 scopus 로고    scopus 로고
    • Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6
    • Yang F, Li X, Sharma M, Zarnegar M, Lim B, Sun Z. 2001. Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. J Biol Chem 276:15345-15353.
    • (2001) J Biol Chem , vol.276 , pp. 15345-15353
    • Yang, F.1    Li, X.2    Sharma, M.3    Zarnegar, M.4    Lim, B.5    Sun, Z.6
  • 49
    • 33745185532 scopus 로고    scopus 로고
    • MRNPs, polysomes or granules: FMRP in neuronal protein synthesis
    • DOI 10.1016/j.conb.2006.05.010, PII S0959438806000614
    • Zalfa F, Achsel T, Bagni C. 2006. mRNPs, polysomes or granules: FMRP in neuronal protein synthesis. Curr Opin Neurobiol 16:265-269. (Pubitemid 43913459)
    • (2006) Current Opinion in Neurobiology , vol.16 , Issue.3 , pp. 265-269
    • Zalfa, F.1    Achsel, T.2    Bagni, C.3
  • 50
    • 34249982906 scopus 로고    scopus 로고
    • Nuclear export and cytoplasmic maturation of ribosomal subunits
    • DOI 10.1016/j.febslet.2007.05.013, PII S0014579307005376, Vienna Special Issue: Molecular Machines
    • Zemp I, Kutay U. 2007. Nuclear export and cytoplasmic maturation of ribosomal subunits. FEBS Lett 581:2783-2793. (Pubitemid 46881154)
    • (2007) FEBS Letters , vol.581 , Issue.15 , pp. 2783-2793
    • Zemp, I.1    Kutay, U.2
  • 51
    • 0037144861 scopus 로고    scopus 로고
    • P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration
    • Zhang H, Li Z, Viklund EK, Strömblad S. 2002. P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration. J Cell Biol 158:1287-1297.
    • (2002) J Cell Biol , vol.158 , pp. 1287-1297
    • Zhang, H.1    Li, Z.2    Viklund, E.K.3    Strömblad, S.4
  • 52
    • 14844293207 scopus 로고    scopus 로고
    • PAK and other Rho-associated kinases - Effectors with surprisingly diverse mechanisms of regulation
    • DOI 10.1042/BJ20041638
    • Zhao ZS, Manser E. 2005. PAK and other Rho-associated kinases - Effectors with surprisingly diverse mechanisms of regulation. Biochem J 386:201-214. (Pubitemid 40343777)
    • (2005) Biochemical Journal , vol.386 , Issue.2 , pp. 201-214
    • Zhao, Z.-S.1    Manser, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.