메뉴 건너뛰기




Volumn 44, Issue 7-8, 2010, Pages 1271-1286

A review of oral antiretroviral therapy for the treatment of chronic hepatitis B

Author keywords

Adefovir; Chronic hepatitis B; Clevudine; Emtricitabine; Entecavir; Lamivudine; Nucleoside inhibitor; Nucleotide inhibitor; Pradefovir; Telbivudine; Tenofovir

Indexed keywords

ADEFOVIR; ADEFOVIR DIPIVOXIL; ANTIRETROVIRUS AGENT; CLEVUDINE; EMTRICITABINE; ENTECAVIR; LAMIVUDINE; PRADEFOVIR; TELBIVUDINE; TENOFOVIR; TENOFOVIR DISOPROXIL; VIRUS DNA;

EID: 77954593322     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1M590     Document Type: Review
Times cited : (10)

References (89)
  • 1
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • DOI 10.1056/NEJMra0801644
    • Dienstag J. Hepatitis B virus infection. N Engl J Med 2008;259;1486-500. DOI 10.1056/NEJMra0801644
    • (2008) N Engl J Med , vol.259 , pp. 1486-1500
    • Dienstag, J.1
  • 2
    • 76749152895 scopus 로고    scopus 로고
    • Chronic hepatitis B: Update 2009 (AASLD Practice Guidelines)
    • DOI 10.1002/hep.00000
    • Lok AS, McMahon BJ. Chronic hepatitis B: update 2009 (AASLD Practice Guidelines). Hepatology 2009;50:1-36. DOI 10.1002/hep.00000
    • (2009) Hepatology , vol.50 , pp. 1-36
    • Lok, A.S.1    McMahon, B.J.2
  • 3
    • 77954601407 scopus 로고    scopus 로고
    • Update on pharmacotherapy of chronic hepatitis B and C
    • Chessman KH, ed. 6th ed. Kansas City, MO: American College of Clinical Pharmacy
    • Corey RL. Update on pharmacotherapy of chronic hepatitis B and C. In: Chessman KH, ed. Gastroenterology I and II and nutrition - PSAP VI, book 9. 6th ed. Kansas City, MO: American College of Clinical Pharmacy, 2009:1-24.
    • (2009) Gastroenterology I and II and Nutrition - PSAP VI, Book 9 , pp. 1-24
    • Corey, R.L.1
  • 4
    • 32444435768 scopus 로고    scopus 로고
    • HBV drug resistance: Mechanisms, detection and interpretation
    • DOI 10.1016/j.jhep.2006.01.001, PII S016882780600002X
    • Shaw T, Bartholomeusz A, Locarnini S. HBV drug resistance: mechanisms, detection and interpretation. J Hepatol 2006;44:593-606. DOI 10.1016/j.jhep.2006.01.001 (Pubitemid 43227885)
    • (2006) Journal of Hepatology , vol.44 , Issue.3 , pp. 593-606
    • Shaw, T.1    Bartholomeusz, A.2    Locarnini, S.3
  • 5
    • 0033592764 scopus 로고    scopus 로고
    • Lamivudine as initial treatment for chronic hepatitis B in the United States
    • DOI 10.1056/NEJM199910213411702
    • Dienstag JL, Schiff ER, Wright TL, et al. Lamivudine as initial treatment for chronic hepatitis B in the United States. N Engl J Med 1999; 341:1256-63. DOI 10.1056/NEJM199910213411702
    • (1999) N Engl J Med , vol.341 , pp. 1256-1263
    • Dienstag, J.L.1    Schiff, E.R.2    Wright, T.L.3
  • 6
    • 0033012793 scopus 로고    scopus 로고
    • Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B
    • Lamivudine Precore Mutant Study Group DOI 10.1002/hep.510290321
    • Tassopoulos NC, Volpes R, Pastore G, et al. Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Lamivudine Precore Mutant Study Group. Hepatology 1999;29:889-96. DOI 10.1002/hep.510290321
    • (1999) Hepatology , vol.29 , pp. 889-896
    • Tassopoulos, N.C.1    Volpes, R.2    Pastore, G.3
  • 7
    • 0031780935 scopus 로고    scopus 로고
    • Identification and characterization of mutations in hepatitis B virus resistant to lamivudine
    • Lamivudine Clinical Investigation Group DOI 10.1002/hep.510270628
    • Allen MI, Deslauriers M, Andrews CW, et al. Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group. Hepatology 1998;27:1670-7. DOI 10.1002/hep.510270628
    • (1998) Hepatology , vol.27 , pp. 1670-1677
    • Allen, M.I.1    Deslauriers, M.2    Andrews, C.W.3
  • 8
    • 10744225554 scopus 로고    scopus 로고
    • Long-term safety of lamivudine treatment in patients with chronic hepatitis B
    • DOI 10.1053/j.gastro.2003.09.033
    • Lok AS, Lai CL, Leung N, et al. Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology 2003;125:1714-22. DOI 10.1053/j.gastro.2003.09.033
    • (2003) Gastroenterology , vol.125 , pp. 1714-1722
    • Lok, A.S.1    Lai, C.L.2    Leung, N.3
  • 9
    • 0034802516 scopus 로고    scopus 로고
    • Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy
    • DOI 10.1053/jhep.2001.27563
    • Yuen MF, Sablon E, Hui CK, Yuan HJ, Decraemer H, Lai CL. Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy. Hepatology 2001;34:751-7. DOI 10.1053/jhep.2001. 27563
    • (2001) Hepatology , vol.34 , pp. 751-757
    • Yuen, M.F.1    Sablon, E.2    Hui, C.K.3    Yuan, H.J.4    Decraemer, H.5    Lai, C.L.6
  • 10
    • 0036288645 scopus 로고    scopus 로고
    • Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease
    • DOI 10.1053/jhep.2002.33894
    • Papatheodoridis GV, Dimou E, Laras A, Papadimitropoulos V, Hadziyannis SJ. Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease. Hepatology 2002;36:219-26. DOI 10.1053/jhep.2002.33894
    • (2002) Hepatology , vol.36 , pp. 219-226
    • Papatheodoridis, G.V.1    Dimou, E.2    Laras, A.3    Papadimitropoulos, V.4    Hadziyannis, S.J.5
  • 11
    • 0037221907 scopus 로고    scopus 로고
    • Histological outcome during long-term lamivudine therapy
    • DOI 10.1053/gast.2003.50013
    • Dienstag JL, Goldin RD, Heathcote EJ, et al. Histological outcome during long-term lamivudine therapy. Gastroenterology 2003;124:105-17. DOI 10.1053/gast.2003.50013
    • (2003) Gastroenterology , vol.124 , pp. 105-117
    • Dienstag, J.L.1    Goldin, R.D.2    Heathcote, E.J.3
  • 12
    • 0032783679 scopus 로고    scopus 로고
    • Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
    • DOI 10.1002/hep.510300221
    • Liaw YF, Chien RN, Yeh CT, Tsai SL, Chu CM. Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 1999;30:567-72. DOI 10.1002/hep.510300221
    • (1999) Hepatology , vol.30 , pp. 567-572
    • Liaw, Y.F.1    Chien, R.N.2    Yeh, C.T.3    Tsai, S.L.4    Chu, C.M.5
  • 13
    • 38049087457 scopus 로고    scopus 로고
    • Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease
    • Yuen MF, Seto WK, Chow DH, et al. Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease. Antivir Ther 2007;12:1295-303.
    • (2007) Antivir Ther , vol.12 , pp. 1295-1303
    • Yuen, M.F.1    Seto, W.K.2    Chow, D.H.3
  • 14
    • 33646369149 scopus 로고    scopus 로고
    • Antiviral drug resistance: Clinical consequences and molecular aspects
    • DOI 10.1055/s-2006-939758
    • Bartholomeusz A, Locarnini SA. Antiviral drug resistance: clinical consequences and molecular aspects. Semin Liver Dis 2006;26:162-70. DOI 10.1055/s-2006-939758
    • (2006) Semin Liver Dis , vol.26 , pp. 162-170
    • Bartholomeusz, A.1    Locarnini, S.A.2
  • 15
    • 70349240414 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • DOI 10.1002/hep.23190
    • Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology 2009;50:661-2. DOI 10.1002/hep.23190
    • (2009) Hepatology , vol.50 , pp. 661-662
    • Lok, A.S.1    McMahon, B.J.2
  • 16
    • 49849099939 scopus 로고    scopus 로고
    • Care of HIV patients with chronic hepatitis B: Updated recommendations from the HIV-Hepatitis B Virus International Panel
    • DOI 10.1097/QAD.0b013e3282f8b46f
    • Soriano V, Puoti M, Peters M, et al. Care of HIV patients with chronic hepatitis B: updated recommendations from the HIV-Hepatitis B Virus International Panel. AIDS 2008;22:1399-410. DOI 10.1097/QAD.0b013e3282f8b46f
    • (2008) AIDS , vol.22 , pp. 1399-1410
    • Soriano, V.1    Puoti, M.2    Peters, M.3
  • 17
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • DOI 10.1056/NEJMoa051285
    • Chang TT, Gish RG, de Man R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 2006;354:1001-10. DOI 10.1056/NEJMoa051285
    • (2006) N Engl J Med , vol.354 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    De Man, R.3
  • 18
    • 34548494824 scopus 로고    scopus 로고
    • A one-year trial of entecavir treatment in patients with HBeAg-positive chronic hepatitis B
    • Ren FY, Piao DM, Piao XX. A one-year trial of entecavir treatment in patients with HBeAg-positive chronic hepatitis B. World J Gastroenterol 2007;13:4264-7.
    • (2007) World J Gastroenterol , vol.13 , pp. 4264-4267
    • Ren, F.Y.1    Piao, D.M.2    Piao, X.X.3
  • 19
    • 57149089345 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir compared to lamivudine in nucleoside-naïve patients with chronic hepatitis B: A randomized double-blind trial in China
    • DOI 10.1007/s12072-007-9009-2
    • Yao G, Chen CW, Lu WL, et al. Efficacy and safety of entecavir compared to lamivudine in nucleoside-naïve patients with chronic hepatitis B: a randomized double-blind trial in China. Hepatol Int 2007;1:365-72. DOI 10.1007/s12072-007-9009-2
    • (2007) Hepatol Int , vol.1 , pp. 365-372
    • Yao, G.1    Chen, C.W.2    Lu, W.L.3
  • 20
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • DOI 10.1056/NEJMoa051287
    • Lai CL, Shouval D, Lok AS, et al. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med 2006;354:1011-21. DOI 10.1056/NEJMoa051287
    • (2006) N Engl J Med , vol.354 , pp. 1011-1021
    • Lai, C.L.1    Shouval, D.2    Lok, A.S.3
  • 21
    • 35649020315 scopus 로고    scopus 로고
    • Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B
    • DOI 10.1053/j.gastro.2007.08.024
    • Gish RG, Lok AS, Chang TT, et al. Entecavir therapy for up to 96 weeks in patients with HBeAg-positive chronic hepatitis B. Gastroenterology 2007;133:1437-44. DOI 10.1053/j.gastro.2007.08.024
    • (2007) Gastroenterology , vol.133 , pp. 1437-1444
    • Gish, R.G.1    Lok, A.S.2    Chang, T.T.3
  • 22
    • 57149101516 scopus 로고    scopus 로고
    • Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naïve Chinese patients with chronic hepatitis B: A randomized, multicenter study
    • DOI 10.1007/s12072-008-9088-8
    • Yao G, Chen CW, Lu WL, et al. Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naïve Chinese patients with chronic hepatitis B: a randomized, multicenter study. Hepatol Int 2008;2:486-93. DOI 10.1007/s12072-008-9088-8
    • (2008) Hepatol Int , vol.2 , pp. 486-493
    • Yao, G.1    Chen, C.W.2    Lu, W.L.3
  • 23
    • 33744531146 scopus 로고    scopus 로고
    • Entecavir for treatment of lamivudine-refractory, HBeAg-positive chronic hepatitis B
    • DOI 10.1053/j.gastro.2006.04.007
    • Sherman M, Yurdaydin C, Sollano J, et al. Entecavir for treatment of lamivudine-refractory, HBeAg-positive chronic hepatitis B. Gastroenterology 2006;130:2039-49. DOI 10.1053/j.gastro.2006.04.007
    • (2006) Gastroenterology , vol.130 , pp. 2039-2049
    • Sherman, M.1    Yurdaydin, C.2    Sollano, J.3
  • 24
    • 49849099655 scopus 로고    scopus 로고
    • Efficacy and safety of entecavir in lamivudine-refractory patients with chronic hepatitis B: Randomized controlled trial in Japanese patients
    • DOI 10.1111/j.1440-1746.2008.05455.x
    • Suzuki F, Toyoda J, Katano Y, et al. Efficacy and safety of entecavir in lamivudine-refractory patients with chronic hepatitis B: randomized controlled trial in Japanese patients. J Gastrol Hepatol 2008;23:1320-6. DOI 10.1111/j.1440-1746.2008.05455.x
    • (2008) J Gastrol Hepatol , vol.23 , pp. 1320-1326
    • Suzuki, F.1    Toyoda, J.2    Katano, Y.3
  • 25
    • 69349083026 scopus 로고    scopus 로고
    • Lamivudine-to-entecavir switching treatment in type B chronic hepatitis patients without evidence of lamivudine resistance
    • DOI 10.1007/s00535-009-0076-0
    • Kurashige N, Ohkawa K, Hiramatsu N, et al. Lamivudine-to-entecavir switching treatment in type B chronic hepatitis patients without evidence of lamivudine resistance. J Gastroenterol 2009;44:864-70. DOI 10.1007/s00535-009- 0076-0
    • (2009) J Gastroenterol , vol.44 , pp. 864-870
    • Kurashige, N.1    Ohkawa, K.2    Hiramatsu, N.3
  • 26
    • 58149316191 scopus 로고    scopus 로고
    • Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: The case for continuous antiviral therapy
    • DOI 10.1016/j.jhep.2008.10.017
    • Shouval D, Lai CL, Chang TT, et al. Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: the case for continuous antiviral therapy. J Hepatol 2009;50:289-95. DOI 10.1016/j.jhep.2008.10.017
    • (2009) J Hepatol , vol.50 , pp. 289-295
    • Shouval, D.1    Lai, C.L.2    Chang, T.T.3
  • 27
    • 58949087420 scopus 로고    scopus 로고
    • Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir
    • DOI 10.1002/hep.22658
    • Leung N, Peng CY, Hann HW, et al. Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: a randomized international study of entecavir versus adefovir. Hepatology 2009;49:72-9. DOI 10.1002/hep.22658
    • (2009) Hepatology , vol.49 , pp. 72-79
    • Leung, N.1    Peng, C.Y.2    Hann, H.W.3
  • 28
    • 33845675367 scopus 로고    scopus 로고
    • Entecavir resistance is rare in nucleoside naïve patients with hepatitis B
    • DOI 10.1002/hep.21422
    • Colonno RJ, Rose R, Baldick CJ, et al. Entecavir resistance is rare in nucleoside naïve patients with hepatitis B. Hepatology 2006;44:1656-65. DOI 10.1002/hep.21422
    • (2006) Hepatology , vol.44 , pp. 1656-1665
    • Colonno, R.J.1    Rose, R.2    Baldick, C.J.3
  • 29
    • 33847701354 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • DOI 10.1002/hep.21513
    • Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology 2007;45:507-39. DOI 10.1002/hep.21513
    • (2007) Hepatology , vol.45 , pp. 507-539
    • Lok, A.S.1    McMahon, B.J.2
  • 30
    • 70349440589 scopus 로고    scopus 로고
    • Early hepatitis B virological rebound on entecavir through selection of lamivudine-associated mutations
    • DOI 10.1093/jac/dkp283
    • Tong CW, Mullen JE, Wong T. Early hepatitis B virological rebound on entecavir through selection of lamivudine-associated mutations. J Antimicrob Chemother 2009;64:875-7. DOI 10.1093/jac/dkp283
    • (2009) J Antimicrob Chemother , vol.64 , pp. 875-877
    • Tong, C.W.1    Mullen, J.E.2    Wong, T.3
  • 31
    • 65049086668 scopus 로고    scopus 로고
    • Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naïve chronic hepatitis B
    • DOI 10.1007/s12072-008-9109-8
    • Kobashi H, Fujioka S, Kawaguchi M, et al. Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naïve chronic hepatitis B. Hepatol Int 2009;3:403-10. DOI 10.1007/s12072-008-9109-8
    • (2009) Hepatol Int , vol.3 , pp. 403-410
    • Kobashi, H.1    Fujioka, S.2    Kawaguchi, M.3
  • 32
    • 33847683844 scopus 로고    scopus 로고
    • Two-year assessment of entecavir resistance in lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present
    • DOI 10.1128/AAC.00833-06
    • Tenney DJ, Rose RE, Baldick CJ, et al. Two-year assessment of entecavir resistance in lamivudine-refractory hepatitis B virus patients reveals different clinical outcomes depending on the resistance substitutions present. J Antimicrob Chemother 2007;51:902-11. DOI 10.1128/AAC.00833-06
    • (2007) J Antimicrob Chemother , vol.51 , pp. 902-911
    • Tenney, D.J.1    Rose, R.E.2    Baldick, C.J.3
  • 33
    • 70350050776 scopus 로고    scopus 로고
    • Efficacy of entecavir in patients with chronic hepatitis B resistant to both lamivudine and adefovir or to lamivudine alone
    • DOI 10.1002/hep.23145
    • Shim JH, Suh DJ, Kim KM, et al. Efficacy of entecavir in patients with chronic hepatitis B resistant to both lamivudine and adefovir or to lamivudine alone. Hepatology 2009;30:1064-71. DOI 10.1002/hep.23145
    • (2009) Hepatology , vol.30 , pp. 1064-1071
    • Shim, J.H.1    Suh, D.J.2    Kim, K.M.3
  • 34
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • DOI 10.1056/NEJMoa020681
    • Marcellin P, Chang TT, Lim SG, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003;348:808-16. DOI 10.1056/NEJMoa020681
    • (2003) N Engl J Med , vol.348 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 35
    • 33745921497 scopus 로고    scopus 로고
    • A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B
    • DOI 10.1002/hep.21225
    • Zeng M, Mao Y, Yao G, et al. A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B. Hepatology 2006;44:108-16. DOI 10.1002/hep.21225
    • (2006) Hepatology , vol.44 , pp. 108-116
    • Zeng, M.1    Mao, Y.2    Yao, G.3
  • 36
    • 0037468406 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B
    • DOI 10.1056/NEJMoa021812
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B. N Engl J Med 2003;348:800-7. DOI 10.1056/NEJMoa021812
    • (2003) N Engl J Med , vol.348 , pp. 800-807
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 37
    • 51349107091 scopus 로고    scopus 로고
    • Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis Be antigen-positive chronic hepatitis B
    • DOI 10.1002/hep.22414
    • Marcellin P, Chang TT, Lim SG, et al. Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis Be antigen-positive chronic hepatitis B. Hepatology 2008;48:750-8. DOI 10.1002/hep.22414
    • (2008) Hepatology , vol.48 , pp. 750-758
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 38
    • 21244455293 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B
    • DOI 10.1056/NEJMoa042957
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B. N Engl J Med 2005;352:2673-81. DOI 10.1056/NEJMoa042957
    • (2005) N Engl J Med , vol.352 , pp. 2673-2681
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 39
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • DOI 10.1053/j.gastro.2006/09.020
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology 2006;131:1743-51. DOI 10.1053/j.gastro.2006/09.020
    • (2006) Gastroenterology , vol.131 , pp. 1743-1751
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 41
    • 33947427581 scopus 로고    scopus 로고
    • Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: Final long-term results
    • DOI 0.1002/lt.20981
    • Schiff E, Lai CL, Hadziyannis S, et al. Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: final long-term results. Liver Transpl 2007;13:349-60. DOI 0.1002/lt.20981
    • (2007) Liver Transpl , vol.13 , pp. 349-360
    • Schiff, E.1    Lai, C.L.2    Hadziyannis, S.3
  • 42
    • 0041853784 scopus 로고    scopus 로고
    • Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase
    • DOI 10.1016/S0016-5085(03)00939-9
    • Angus P, Vaughan R, Xiong S, et al. Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase. Gastroenterology 2003;125:292-7. DOI 10.1016/S0016-5085(03)00939-9
    • (2003) Gastroenterology , vol.125 , pp. 292-297
    • Angus, P.1    Vaughan, R.2    Xiong, S.3
  • 43
    • 0346243783 scopus 로고    scopus 로고
    • Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient
    • DOI 10.1016/j.jhep.2003.09.022
    • Villeneuve JP, Durantel D, Durantel S, et al. Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient. J Hepatol 2003;39:1085-9. DOI 10.1016/j.jhep.2003.09.022
    • (2003) J Hepatol , vol.39 , pp. 1085-1089
    • Villeneuve, J.P.1    Durantel, D.2    Durantel, S.3
  • 44
    • 27144488889 scopus 로고    scopus 로고
    • Incidence and predictors of emergence of adefovir resistant HBV during four years of adefovir dipivoxil therapy for patients with chronic hepatitis B
    • abstract
    • Locarnini S, Qi X, Arterburn S, et al. Incidence and predictors of emergence of adefovir resistant HBV during four years of adefovir dipivoxil therapy for patients with chronic hepatitis B (abstract). J Hepatol 2005;42:17A.
    • (2005) J Hepatol , vol.42
    • Locarnini, S.1    Qi, X.2    Arterburn, S.3
  • 45
    • 51349107091 scopus 로고    scopus 로고
    • Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • DOI 10.1002/hep.22414
    • Marcellin P, Chang TT, Lim SG, et al. Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. Hepatology 2008;48:750-8. DOI 10.1002/hep.22414
    • (2008) Hepatology , vol.48 , pp. 750-758
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 46
    • 77954577407 scopus 로고    scopus 로고
    • Package insert Foster City, CA: Gilead Sciences, November
    • Package insert. Viread (tenofovir). Foster City, CA: Gilead Sciences, November 2008.
    • (2008) Viread (Tenofovir)
  • 47
    • 57349095400 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
    • DOI 10.1056/NEJMoa0802878
    • Marcellin P, Heathcote EJ, Buti M, et al. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N Engl J Med 2008;359:2442-55. DOI 10.1056/NEJMoa0802878
    • (2008) N Engl J Med , vol.359 , pp. 2442-2455
    • Marcellin, P.1    Heathcote, E.J.2    Buti, M.3
  • 48
    • 10644275213 scopus 로고    scopus 로고
    • Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection
    • DOI 10.1002/hep.20464
    • Van Brommel F, Wunsche T, Mauss S, et al. Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection. Hepatology 2004;40:1421-5. DOI 10.1002/hep.20464
    • (2004) Hepatology , vol.40 , pp. 1421-1425
    • Van Brommel, F.1    Wunsche, T.2    Mauss, S.3
  • 49
    • 42049103348 scopus 로고    scopus 로고
    • A randomized, double-blind, comparison of tenofovir (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg-negative chronic hepatitis B (CHB): Study GS-US-174-0102
    • abstract
    • Marcellin P, Buti M, Krastev Z, et al. A randomized, double-blind, comparison of tenofovir (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg-negative chronic hepatitis B (CHB): study GS-US-174-0102 (abstract). Hepatology 2007;46:80A.
    • (2007) Hepatology , vol.46
    • Marcellin, P.1    Buti, M.2    Krastev, Z.3
  • 50
    • 39149122593 scopus 로고    scopus 로고
    • A randomized double-blind, comparison of tenofovir DF (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg-positive chronic hepatitis B (CHB): Study GS-US-174-0103
    • abstract
    • Heathcote EJ, Gane E, DeMan R, et al. A randomized double-blind, comparison of tenofovir DF (TDF) versus adefovir dipivoxil (ADV) for the treatment of HBeAg-positive chronic hepatitis B (CHB): study GS-US-174-0103 (abstract). Hepatology 2007;46:861A.
    • (2007) Hepatology , vol.46
    • Heathcote, E.J.1    Gane, E.2    DeMan, R.3
  • 51
    • 34548278800 scopus 로고    scopus 로고
    • Low-dose tenofovir is more potent than adefovir and is effective in controlling HBV viremia in chronic HBeAg-negative hepatitis B
    • Poggio PD, Zaccanelli M, Oggionni M, Colombo S, Jamoletti C, Puhalo V. Low-dose tenofovir is more potent than adefovir and is effective in controlling HBV viremia in chronic HBeAg-negative hepatitis B. World J Gastroenterol 2007;13:4096-9.
    • (2007) World J Gastroenterol , vol.13 , pp. 4096-4099
    • Poggio, P.D.1    Zaccanelli, M.2    Oggionni, M.3    Colombo, S.4    Jamoletti, C.5    Puhalo, V.6
  • 52
    • 32644436203 scopus 로고    scopus 로고
    • Successful rescue therapy with tenofovir in a patient with hepatic decompensation and adefovir resistant HBV mutant
    • DOI 10.1186/1476-5926-5-1
    • Ratziu V, Thibault V, Benhamou Y, Poynard T. Successful rescue therapy with tenofovir in a patient with hepatic decompensation and adefovir resistant HBV mutant. Comp Hepatol 2006;5:1-4. DOI 10.1186/1476-5926-5-1
    • (2006) Comp Hepatol , vol.5 , pp. 1-4
    • Ratziu, V.1    Thibault, V.2    Benhamou, Y.3    Poynard, T.4
  • 53
    • 33747041958 scopus 로고    scopus 로고
    • Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy
    • DOI 10.1002/hep.21253
    • Van Brommel F, Vernhard Z, Sarrazin C, et al. Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy. Hepatology 2006;44:318-25. DOI 10.1002/hep.21253
    • (2006) Hepatology , vol.44 , pp. 318-325
    • Van Brommel, F.1    Vernhard, Z.2    Sarrazin, C.3
  • 54
    • 39149096847 scopus 로고    scopus 로고
    • Tenofovir monotherapy is effective in hepatitis B patients with antiviral treatment failure to adefovir in the absence of adefovir-resistant mutations
    • DOI 10.1016/j.jhep.2007.09.202
    • Tan J, Degertekin B, Wong SN, Husain M, Oberhelman K, Lok AS. Tenofovir monotherapy is effective in hepatitis B patients with antiviral treatment failure to adefovir in the absence of adefovir-resistant mutations. J Hepatol 2008;48:391-8. DOI 10.1016/j.jhep.2007.09.202
    • (2008) J Hepatol , vol.48 , pp. 391-398
    • Tan, J.1    Degertekin, B.2    Wong, S.N.3    Husain, M.4    Oberhelman, K.5    Lok, A.S.6
  • 55
    • 77958193712 scopus 로고    scopus 로고
    • Two year tenofovir disoproxil fumarate (TDF) treatment and adefovir dipivoxil (ADV) switch data in HBeAg-positive patients with chronic hepatitis B: Study 103
    • Presented at
    • Heathcote EJ, Gane E, deMan R, et al. Two year tenofovir disoproxil fumarate (TDF) treatment and adefovir dipivoxil (ADV) switch data in HBeAg-positive patients with chronic hepatitis B: study 103. Presented at: 13th International Symposium on Viral Hepatitis and Liver Disease, 2009.
    • 13th International Symposium on Viral Hepatitis and Liver Disease, 2009
    • Heathcote, E.J.1    Gane, E.2    DeMan, R.3
  • 56
    • 19944430564 scopus 로고    scopus 로고
    • Tenofovir therapy for lamivudine resistance following liver transplantation
    • DOI 10.1345/aph.1E280
    • Neff GW, Nery J, Lau DTY, et al. Tenofovir therapy for lamivudine resistance following liver transplantation. Ann Pharmacother 2004;38:1999-2004. DOI 10.1345/aph.1E280
    • (2004) Ann Pharmacother , vol.38 , pp. 1999-2004
    • Neff, G.W.1    Nery, J.2    Lau, D.T.Y.3
  • 57
    • 34047190745 scopus 로고    scopus 로고
    • Treatment of patients with lamivudine-resistant and adefovir dipivoxil-resistant chronic hepatitis B virus infection: Is tenofovir the answer?
    • DOI 10.1136/gut.2006.108928
    • Trojan J, Stuermer M, Teuber G, Berger A, Gaust D. Treatment of patients with lamivudine-resistant and adefovir dipivoxil-resistant chronic hepatitis B virus infection: is tenofovir the answer? Gut 2007;56:436. DOI 10.1136/gut.2006.108928
    • (2007) Gut , vol.56 , pp. 436
    • Trojan, J.1    Stuermer, M.2    Teuber, G.3    Berger, A.4    Gaust, D.5
  • 58
    • 53249154274 scopus 로고    scopus 로고
    • Does the presence of adefovir-resistant variants lead to failure of tenofovir monotherapy?
    • DOI 10.1016/j.jhep.2008.08.001
    • Deterding K, Manns MP, Wedemeyer H. Does the presence of adefovir-resistant variants lead to failure of tenofovir monotherapy? J Hepatol 2008;49:862. DOI 10.1016/j.jhep.2008.08.001
    • (2008) J Hepatol , vol.49 , pp. 862
    • Deterding, K.1    Manns, M.P.2    Wedemeyer, H.3
  • 59
    • 51049122209 scopus 로고    scopus 로고
    • Tenofovir (TDF) has stronger antiviral effect than adefovir (ADV) against lamivudine (LAM)-resistant hepatitis B virus (HBV)
    • DOI 10.1007/s12072-008-9045-6
    • Hann HW, Chaw HB, Dunn SR. Tenofovir (TDF) has stronger antiviral effect than adefovir (ADV) against lamivudine (LAM)-resistant hepatitis B virus (HBV). Hepatol Int 2008;2:244-9. DOI 10.1007/s12072-008-9045-6
    • (2008) Hepatol Int , vol.2 , pp. 244-249
    • Hann, H.W.1    Chaw, H.B.2    Dunn, S.R.3
  • 60
    • 65649147137 scopus 로고    scopus 로고
    • Hepatitis B virus mutations potentially conferring adefovir/tenofovir resistance in treatment-naïve patients
    • Pastor R, Habersetzer F, Fafi-Kremer S, et al. Hepatitis B virus mutations potentially conferring adefovir/tenofovir resistance in treatment-naïve patients. World J Gastroenterol 2009;15:753-5.
    • (2009) World J Gastroenterol , vol.15 , pp. 753-755
    • Pastor, R.1    Habersetzer, F.2    Fafi-Kremer, S.3
  • 61
    • 58649096155 scopus 로고    scopus 로고
    • 2-Year GLOBE trial results: Telbivudine is superior to lamivudine in patients with chronic hepatitis B
    • DOI 10.1053/j.gastro.2008.10.026
    • Liaw YF, Gane E, Leung N, et al. 2-Year GLOBE trial results: telbivudine is superior to lamivudine in patients with chronic hepatitis B. Gastroenterology 2009;136:486-95. DOI 10.1053/j.gastro.2008.10.026
    • (2009) Gastroenterology , vol.136 , pp. 486-495
    • Liaw, Y.F.1    Gane, E.2    Leung, N.3
  • 62
    • 37349120537 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in patients with chronic hepatitis B
    • DOI 10.1056/NEJMoa066422
    • Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med 2007;357:2576-88. DOI 10.1056/NEJMoa066422
    • (2007) N Engl J Med , vol.357 , pp. 2576-2588
    • Lai, C.L.1    Gane, E.2    Liaw, Y.F.3
  • 63
    • 67349178133 scopus 로고    scopus 로고
    • Baseline characteristics and early ontreatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B
    • DOI 10.1016/j.jhep.2008.12.019
    • Zeuzem S, Gane E, Liaw YF, et al. Baseline characteristics and early ontreatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B. J Hepatol 2009;51:11-20. DOI 10.1016/j.jhep.2008.12.019
    • (2009) J Hepatol , vol.51 , pp. 11-20
    • Zeuzem, S.1    Gane, E.2    Liaw, Y.F.3
  • 64
    • 38449093445 scopus 로고    scopus 로고
    • Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: A randomized trial
    • Chan HL, Heathcote EJ, Marcellin P, et al. Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial. Ann Intern Med 2007;147:745-54.
    • (2007) Ann Intern Med , vol.147 , pp. 745-754
    • Chan, H.L.1    Heathcote, E.J.2    Marcellin, P.3
  • 65
    • 36348947122 scopus 로고    scopus 로고
    • 76 week follow up of HBeAg positive chronic hepatitis B patients treated with telbivudine, adefovir or switched from adefovir to telbivudine
    • abstract 124
    • Marcellin P, Chan HL, Lai CL, et al. 76 week follow up of HBeAg positive chronic hepatitis B patients treated with telbivudine, adefovir or switched from adefovir to telbivudine (abstract 124). J Hepatol 2007;46:S55.
    • (2007) J Hepatol , vol.46
    • Marcellin, P.1    Chan, H.L.2    Lai, C.L.3
  • 66
    • 58149459587 scopus 로고    scopus 로고
    • Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross resistance profile than the nucleotide analog inhibitors adefovir and tenofovir
    • DOI 10.1016/j.antiviral.2008.10.008
    • Seifer M, Patty A, Serra I, Li B, Standring DN. Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross resistance profile than the nucleotide analog inhibitors adefovir and tenofovir. Antiviral Res 2009;81:147-55. DOI 10.1016/j.antiviral.2008.10.008
    • (2009) Antiviral Res , vol.81 , pp. 147-155
    • Seifer, M.1    Patty, A.2    Serra, I.3    Li, B.4    Standring, D.N.5
  • 67
    • 77954584040 scopus 로고    scopus 로고
    • Package insert Foster City, CA: Gilead Sciences, May
    • Package insert. Emtriva (emtricitabine) Foster City, CA: Gilead Sciences, May 2008.
    • (2008) Emtriva (Emtricitabine)
  • 68
    • 0036093269 scopus 로고    scopus 로고
    • Dose range study of pharmacokinetics, safety, and preliminary antiviral activity of emtricitabine in adults with hepatitis B virus infection
    • DOI 10.1128/AAC.46.6.1734-1740.2002
    • Gish RG, Leung NW, Wright TL, et al. Dose range study of pharmacokinetics, safety, and preliminary antiviral activity of emtricitabine in adults with hepatitis B virus infection. Antimicrob Agents Chemother 2002;46:1734-40. DOI 10.1128/AAC.46.6.1734-1740.2002
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1734-1740
    • Gish, R.G.1    Leung, N.W.2    Wright, T.L.3
  • 69
    • 20444416688 scopus 로고    scopus 로고
    • Safety and antiviral activity of emtricitabine (FTC) for the treatment of chronic hepatitis B infection: A two-year study
    • DOI 10.1016/j.jhep.2005/02.017
    • Gish RG, Trinh H, Leung N, et al. Safety and antiviral activity of emtricitabine (FTC) for the treatment of chronic hepatitis B infection: a two-year study. J Hepatol 2005;43:60-6. DOI 10.1016/j.jhep.2005/02.017
    • (2005) J Hepatol , vol.43 , pp. 60-66
    • Gish, R.G.1    Trinh, H.2    Leung, N.3
  • 70
    • 30344457555 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of emtricitabine in chronic hepatitis B
    • DOI 10.1001/archinte.166.1.49
    • Lim SG, Ng TM, King N, et al. A double-blind placebo-controlled study of emtricitabine in chronic hepatitis B. Arch Intern Med 2006;166:49-56. DOI 10.1001/archinte.166.1.49
    • (2006) Arch Intern Med , vol.166 , pp. 49-56
    • Lim, S.G.1    Ng, T.M.2    King, N.3
  • 71
    • 33749515464 scopus 로고    scopus 로고
    • Clevudine: A potent inhibitor of hepatitis B virus in vitro and in vivo
    • DOI 10.1586/14787210.4.4549
    • Korba BE, Furman PA, Otto MJ. Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo. Expert Rev Anti Infect Ther 2006;4:549-61. DOI 10.1586/14787210.4.4549
    • (2006) Expert Rev Anti Infect Ther , vol.4 , pp. 549-561
    • Korba, B.E.1    Furman, P.A.2    Otto, M.J.3
  • 72
    • 3042782464 scopus 로고    scopus 로고
    • A Phase II dose-escalating trial of clevudine in patients with chronic hepatitis B
    • DOI 10.1002/hep.20257
    • Marcellin P, Mommeja-Martin H, Sacks SL, et al. A Phase II dose-escalating trial of clevudine in patients with chronic hepatitis B. Hepatology 2004;40:140-8. DOI 10.1002/hep.20257
    • (2004) Hepatology , vol.40 , pp. 140-148
    • Marcellin, P.1    Mommeja-Martin, H.2    Sacks, S.L.3
  • 73
    • 43849084211 scopus 로고    scopus 로고
    • Clinical trial: A phase II, randomized study evaluating the safety, pharmacokinetics and anti-viral activity of clevudine for 12 weeks in patients with chronic hepatitis B
    • DOI 10.1111/j.1365-2036.2008.03686.x
    • Lim SG, Leung N, Hann HWL, et al. Clinical trial: a phase II, randomized study evaluating the safety, pharmacokinetics and anti-viral activity of clevudine for 12 weeks in patients with chronic hepatitis B. Aliment Pharmacol Ther 2008;27:1282-92. DOI 10.1111/j.1365-2036.2008.03686.x
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 1282-1292
    • Lim, S.G.1    Leung, N.2    Hann, H.W.L.3
  • 74
    • 33646585175 scopus 로고    scopus 로고
    • A 12 week clevudine therapy showed potent and durable antiviral activity in HBe-positive chronic hepatitis B
    • DOI 10.1002/hep.21166
    • Lee HS, Chung YW, Lee KS, et al. A 12 week clevudine therapy showed potent and durable antiviral activity in HBe-positive chronic hepatitis B. Hepatology 2006;43:982-8. DOI 10.1002/hep.21166
    • (2006) Hepatology , vol.43 , pp. 982-988
    • Lee, H.S.1    Chung, Y.W.2    Lee, K.S.3
  • 75
    • 34447647491 scopus 로고    scopus 로고
    • Clevudine therapy for 24 weeks further reduced serum hepatitis B virus DNA levels and increased ALT normalization rates without emergence of viral breakthrough than 12 weeks of clevudine therapy
    • DOI 10.1159/000105442
    • Lee KS, Byun KS, Chung, et al. Clevudine therapy for 24 weeks further reduced serum hepatitis B virus DNA levels and increased ALT normalization rates without emergence of viral breakthrough than 12 weeks of clevudine therapy. Intervirology 2007;50:296-302. DOI 10.1159/000105442
    • (2007) Intervirology , vol.50 , pp. 296-302
    • Lee, K.S.1    Byun, K.S.2    Chung3
  • 76
    • 34248668494 scopus 로고    scopus 로고
    • Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B
    • DOI 10.1002/hep.21629
    • Yoo BC, Kim JH, Chung YH, et al. Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B. Hepatology 2007;45:1172-8. DOI 10.1002/hep.21629
    • (2007) Hepatology , vol.45 , pp. 1172-1178
    • Yoo, B.C.1    Kim, J.H.2    Chung, Y.H.3
  • 77
    • 36348953975 scopus 로고    scopus 로고
    • Clevudine is highly efficacious in hepatitis B with durable off-therapy viral suppression
    • DOI 10.1002/hep.21800
    • Yoo BC, Kim JH, Kim TH, et al. Clevudine is highly efficacious in hepatitis B with durable off-therapy viral suppression. Hepatology 2007;46:1041-8. DOI 10.1002/hep.21800
    • (2007) Hepatology , vol.46 , pp. 1041-1048
    • Yoo, B.C.1    Kim, J.H.2    Kim, T.H.3
  • 78
    • 68549097944 scopus 로고    scopus 로고
    • Clinical and virologic responses to clevudine therapy in chronic hepatitis B patients: Results at 1 year of an open-labeled prospective study
    • Ko SY, Kwon SY, Choe WH, Kim BK, Kim KH, Lee CH. Clinical and virologic responses to clevudine therapy in chronic hepatitis B patients: results at 1 year of an open-labeled prospective study. Antivir Ther 2009;14:585-90.
    • (2009) Antivir Ther , vol.14 , pp. 585-590
    • Ko, S.Y.1    Kwon, S.Y.2    Choe, W.H.3    Kim, B.K.4    Kim, K.H.5    Lee, C.H.6
  • 79
    • 68649086002 scopus 로고    scopus 로고
    • Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA
    • DOI 10.1002/hep.22959
    • Seok JI, Lee DK, Lee CH, et al. Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA. Hepatology 2009;49:2080-6. DOI 10.1002/hep.22959
    • (2009) Hepatology , vol.49 , pp. 2080-2086
    • Seok, J.I.1    Lee, D.K.2    Lee, C.H.3
  • 80
    • 69949133388 scopus 로고    scopus 로고
    • Clevudine myopathy in patients with chronic hepatitis B
    • DOI 10.1002/hep.22959
    • Kim BK, Oh J, Kwon SY, et al. Clevudine myopathy in patients with chronic hepatitis B. J Hepatol 2009;51:829-34. DOI 10.1002/hep.22959
    • (2009) J Hepatol , vol.51 , pp. 829-834
    • Kim, B.K.1    Oh, J.2    Kwon, S.Y.3
  • 81
    • 69949126031 scopus 로고    scopus 로고
    • Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B
    • DOI 10.1016/j.jhep.2009.06.011
    • Fleische RD, Lok ASF. Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B. J Hepatol 2009;51:787-91. DOI 10.1016/j.jhep.2009.06.011
    • (2009) J Hepatol , vol.51 , pp. 787-791
    • Fleische, R.D.1    Lok, A.S.F.2
  • 83
    • 84923546412 scopus 로고    scopus 로고
    • Open-label treatment extension study for patients who complete study RNA200103-201
    • Open-label treatment extension study for patients who complete study RNA200103-201. http://www.clinicaltrials.gov/ct2/show/NCT00230490 (accessed 2010 Mar 22).
    • Accessed 2010 Mar 22
  • 84
    • 20044375767 scopus 로고    scopus 로고
    • Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir
    • DOI 10.1002/hep.20723
    • Brunell MN, Jacquard AC, Pichoud C, et al. Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir. Hepatology 2005;41:1391-8. DOI 10.1002/hep.20723
    • (2005) Hepatology , vol.41 , pp. 1391-1398
    • Brunell, M.N.1    Jacquard, A.C.2    Pichoud, C.3
  • 85
    • 4744350764 scopus 로고    scopus 로고
    • Combinations of adefovir with nucleoside analogs produce additive antiviral effects against hepatitis B virus in vitro
    • DOI 10.1128/AAC.48.10.3702-3710.2004
    • Delaney WE, Yang H, Miller MD, Gibbs CS, Xiong S. Combinations of adefovir with nucleoside analogs produce additive antiviral effects against hepatitis B virus in vitro. Antimicrob Agents Chemother 2004;48:3702-10. DOI 10.1128/AAC.48.10.3702-3710.2004
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3702-3710
    • Delaney, W.E.1    Yang, H.2    Miller, M.D.3    Gibbs, C.S.4    Xiong, S.5
  • 86
    • 39149096847 scopus 로고    scopus 로고
    • Tenofovir monotherapy is effective in hepatitis B patients with antiviral treatment failure to adefovir in the absence of adefovir-resistant mutations
    • DOI 10.1016/j.jhep.2007.12.006
    • Tan J, Degertekin B, Wong SN, Husain M, Oberhelman K, Lok ASF. Tenofovir monotherapy is effective in hepatitis B patients with antiviral treatment failure to adefovir in the absence of adefovir-resistant mutations. J Hepatol 2008;48:391-8. DOI 10.1016/j.jhep.2007.12.006
    • (2008) J Hepatol , vol.48 , pp. 391-398
    • Tan, J.1    Degertekin, B.2    Wong, S.N.3    Husain, M.4    Oberhelman, K.5    Lok, A.S.F.6
  • 87
    • 33750937268 scopus 로고    scopus 로고
    • Effect of switching to tenofovir with emtricitabine in patients with chronic hepatitis B failing to respond to an adefovir-containing regimen
    • DOI 10.1097/01.meg.0000243877.17444.5e
    • Santos SA, Uriel AJ, Park JS, et al. Effect of switching to tenofovir with emtricitabine in patients with chronic hepatitis B failing to respond to an adefovir-containing regimen. Eur J Gastroenterol Hepatol 2006;18:1247-53. DOI 10.1097/01.meg.0000243877.17444.5e
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 1247-1253
    • Santos, S.A.1    Uriel, A.J.2    Park, J.S.3
  • 88
    • 43049168909 scopus 로고    scopus 로고
    • Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: Two-year follow-up
    • DOI 10.1016/j.jhep.2008.02.019
    • Yatsuji H, Suzuki F, Sezaki H, et al. Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: two-year follow-up. J Hepatol 2008;48:923-31. DOI 10.1016/j.jhep.2008.02.019
    • (2008) J Hepatol , vol.48 , pp. 923-931
    • Yatsuji, H.1    Suzuki, F.2    Sezaki, H.3
  • 89
    • 33646438502 scopus 로고    scopus 로고
    • Randomized, double-blind study of emtricitabine (FTC) plus clevudine versus FTC alone in the treatment of chronic hepatitis B
    • DOI 10.1128/AAC.50.5.1642-1648.2006
    • Lim SG, Krastev Z, Ng TM. Randomized, double-blind study of emtricitabine (FTC) plus clevudine versus FTC alone in the treatment of chronic hepatitis B. Antimicrob Agents Chemother 2006;50:1642-8. DOI 10.1128/AAC.50.5.1642-1648.2006
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1642-1648
    • Lim, S.G.1    Krastev, Z.2    Ng, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.