Methamphetamine increases brain viral load and activates natural killer cells in simian immunodeficiency virus-infected monkeys

American Journal of Pathology

Volumn 177, Issue 1, 2010, Pages 355-361

  Marcondes, Maria Cecilia Garibaldi ^a   Flynn, Claudia ^a   Watry, Debbie D ^a   Zandonatti, Michelle ^a   Fox, Howard S ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHAMPHETAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BLOOD SAMPLING; BRAIN; BRAIN INJURY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL ISOLATION; CEREBROSPINAL FLUID; DRUG ABUSE; DRUG BLOOD LEVEL; FLOW CYTOMETRY; HISTOPATHOLOGY; HYPOTHESIS; IMMUNOCOMPETENT CELL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIREMIA; VIRUS INFECTION; VIRUS LOAD;

EID: 77954577011     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090953     Document Type: Article

References (37)

1. Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE: Updated research nosology for HIV-associated neurocognitive disorders. Neurology 2007, 69:1789-1799
2. Kaul M, Zheng J, Okamoto S, Gendelman HE, Lipton SA: HIV-1 infection and AIDS: consequences for the central nervous system, Cell Death Differ 2005, 12(Suppl 1):878-892 (Pubitemid 41038393)
3. Fox HS: Virus-host interaction in the simian immunodeficiency virus-infected brain. J Neurovirol 2008, 14:286-291
4. Kraft-Terry SD, Buch SJ, Fox HS, Gendelman HE: A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection. Neuron 2009, 64:133-145
5. Winslow BT, Voorhees KI, Pehl KA: Methamphetamine abuse. Am Fam Physician 2007, 76:1169-1174
6. Molitor F, Truax SR, Ruiz JD, Sun RK: Association of methamphetamine use during sex with risky sexual behaviors and HIV infection among non-injection drug users. West J Med 1998, 168:93-97 (Pubitemid 28100967)
7. Rotheram-Borus MJ, Luna GC, Marotta T, Kelly H: Going nowhere fast: methamphetamine use and HIV infection. NIDA Res Monogr 1994, 143:155-182
8. Chesney MA, Barrett DC, Stall R: Histories of substance use and risk behavior: precursors to HIV seroconversion in homosexual men. Am J Public Health 1998, 88:113-116
9. Molitor F, Ruiz JD, Flynn N, Mikanda JN, Sun RK, Anderson R: Methamphetamine use and sexual and injection risk behaviors among out-of-treatment injection drug users. Am J Drug Alcohol Abuse 1999, 25:475-493 (Pubitemid 29395142)
10. Vongsheree S, Sri-Ngam P, Ruchusatsawat N, Thaisri H, Puangtabtim W, Phutiprawan T, Sawanpanyalert P: High HIV-1 prevalence among methamphetamine users in central Thailand, 1999-2000. J Med Assoc Thai 2001, 84:1263-1267
11. Kita T, Wagner GC, Nakashima T: Current research on methamphetamine- induced neurotoxicity: animal models of monoamine disruption. J Pharmacol Sci 2003, 92:178-195 (Pubitemid 36992304)
12. Cadet JL, Jayanthi S, Deng X: Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis. FASEB J 2003, 17:1775-1788 (Pubitemid 37214772)
13. LaVoie MJ, Card JP, Hastings TG: Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity. Exp Neurol 2004, 187:47-57 (Pubitemid 38470011)
14. Rippeth JD, Heaton RK, Carey CL, Marcotte TD, Moore DJ, Gonzalez R, Wolfson T, Grant I: Methamphetamine dependence increases risk of neuropsychological impairment in HIV infected persons. J Int Neuropsychol Soc 2004, 10:1-14
15. Ellis RJ, Childers ME, Cherner M, Lazzaretto D, Letendre S, Grant I: Increased human immunodeficiency virus loads in active methamphetamine users are explained by reduced effectiveness of antiretroviral therapy. J Infect Dis 2003, 188:1820-1826
16. Everall I, Salaria S, Roberts E, Corbeil J, Sasik R, Fox H, Grant I, Masliah E: Methamphetamine stimulates interferon inducible genes in HIV infected brain. J Neuroimmunol 2005, 170:158-171
17. Watry D, Lane TE, Streb M, Fox HS: Transfer of neuropathogenic simian immunodeficiency virus with naturally infected microglia. Am J Pathol 1995, 146:914-923
18. Lane TE, Buchmeier MJ, Watry DD, Jakubowski DB, Fox HS: Serial passage of microglial SIV results in selection of homogeneous env quasispecies in the brain. Virology 1995, 212:458-465
19. + T cells in the brain correlate with early central nervous system dysfunction in simian immunodeficiency virus infection. J Immunol 2001, 167:5429-5438
20. Roberts ES, Zandonatti MA, Watry DD, Madden LJ, Henriksen SJ, Taffe MA, Fox HS: Induction of pathogenic sets of genes in macrophages and neurons in neuroAIDS. Am J Pathol 2003, 162:2041-2057
21. Thompson PM, Hayashi KM, Simon SL, Geaga JA, Hong MS, Sui Y, Lee JY, Toga AW, Ling W, London ED: Structural abnormalities in the brains of human subjects who use methamphetamine. J Neurosci 2004, 24:6028-6036
22. Simon SL, Richardson K, Dacey J, Glynn S, Domier CP, Rawson RA, Ling W: A comparison of patterns of methamphetamine and cocaine use. J Addict Dis 2002, 21(1):35-44
23. Alter G, Malenfant JM, Altfeld M: CD107a as a functional marker for the identification of natural killer cell activity. J Immunol Methods 2004, 294:15-22 (Pubitemid 39626587)
24. + peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection. J Neurovirol 2001, 7:528-541
25. Williams KC, Corey S, Westmoreland SV, Pauley D, Knight H, deBakker C, Alvarez X, Lackner AA: Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS. J Exp Med 2001, 193:905-916
26. Liang H, Wang X, Chen H, Song L, Ye L, Wang SH, Wang YJ, Zhou L, Ho WZ: Methamphetamine enhances HIV infection of macrophages. Am J Pathol 2008, 172:1617-1624 (Pubitemid 351793354)
27. Nair MP, Saiyed ZM, Nair N, Gandhi NH, Rodriguez JW, Boukli N, Provencio-Vasquez E, Malow RM, Miguez-Burbano MJ: Methamphetamine enhances HIV-1 infectivity in monocyte derived dendritic cells. J Neuroimmune Pharmacol 2009, 4:129-139
28. Gaskill PJ, Calderon TM, Luers AJ, Eugenin EA, Javitch JA, Berman JW: Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse. Am J Pathol 2009, 175:1148-1159
29. King WD, Larkins S, Hucks-Ortiz C, Wang PC, Gorbach PM, Veniegas R, Shoptaw S: Factors associated with HIV viral load in a respondent driven sample in Los Angeles. AIDS Behav 2009, 13:145-153
30. O'Connell KA, Han Y, Williams TM, Siliciano RF, Blankson JN: Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro. J Virol 2009, 83:5028-5034
31. Choi EI, Reimann KA, Letvin NL: In vivo natural killer cell depletion during primary simian immunodeficiency virus infection in rhesus monkeys. J Virol 2008, 82:6758-6761
32. Basu S, Dasgupta PS: Dopamine, a neurotransmitter, influences the immune system. J Neuroimmunol 2000, 102:113-124
33. Beck G, Brinkkoetter P, Hanusch C, Schulte J, van Ackern K, van der Woude FJ, Yard BA: Clinical review: immunomodulatory effects of dopamine in general inflammation. Crit Care 2004, 8:485-491 (Pubitemid 40073684)
34. Saito M, Yamaguchi T, Kawata T, Ito H, Kanai T, Terada M, Yokosuka M, Saito TR: Effects of methamphetamine on cortisone concentration: NK cell activity and mitogen response of T-lymphocytes in female cynomolgus monkeys. Exp Anim 2006, 55:477-481 (Pubitemid 44741722)
35. Saito M, Terada M, Kawata T, Ito H, Shigematsu N, Kromkhun P, Yokosuka M, Saito TR: Effects of single or repeated administrations of methamphetamine on immune response in mice. Exp Anim 2008, 57:35-43
36. In SW, Son EW, Rhee DK, Pyo S: Methamphetamine administration produces immunomodulation in mice. J Toxicol Environ Health A 2005, 68:2133-2145
37. Segal DS, Kuczenski R: Human methamphetamine pharmacokinetics simulated in the rat: single daily intravenous administration reveals elements of sensitization and tolerance. Neuropsychopharmacology 2006, 31:941-955