Bias and trials stopped early for benefit

JAMA

Volumn 304, Issue 2, 2010, Pages 156-

  Berry, Scott M ^a   Carlin, Bradley P ^b   Connor, Jason ^a  

^a University of Minnesota ^*

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL TENDENCY BIAS; CLINICAL RESEARCH; HUMAN; LETTER; PRIORITY JOURNAL; STUDY DESIGN;

EID: 77954573051     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2010.930     Document Type: Letter

References (2)

1. Bassler D, Briel M, Montori VM, et al; STOPIT-2 Study Group. Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA. 2010;303(12):1180-1187.
2. O'Brien PC, Fleming TR. A multiple testing procedure for clinical trials. Biometrics. 1979;35(3):549-556.