Development and comparison of two multiresidue methods for the analysis of 17 mycotoxins in cereals by liquid chromatography electrospray ionization tandem mass spectrometry

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 13, 2010, Pages 7510-7519

  Desmarchelier, Aurelien ^a   Oberson, Jean Marie ^a   Tella, Patricia ^a   Gremaud, Eric ^a   Seefelder, Walburga ^a   Mottier, Pascal ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Accelerated solvent extraction; LC MS MS; Liquid chromatography tandem mass spectrometry; Multiresidue methods; Mycotoxins; QuEChERS

Indexed keywords

MYCOTOXIN;

ARTICLE; CEREAL; CHEMISTRY; COMPARATIVE STUDY; ELECTROSPRAY MASS SPECTROMETRY; EVALUATION; FOOD CONTAMINATION; LIQUID CHROMATOGRAPHY; METHODOLOGY; SENSITIVITY AND SPECIFICITY; ANALYSIS; EVALUATION STUDY; PROCEDURES;

CEREALS; CHROMATOGRAPHY, LIQUID; FOOD CONTAMINATION; MYCOTOXINS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 77954561786     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf100891m     Document Type: Article

References (36)

1. Hussein, H. S.; Brasel, J. M. Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 2001, 167, 101-134.
2. Delatour, T. Mycotoxins in foodstuffs: Structures, exposure and toxicity. In Envenimations, Intoxinations; EMInter: France, 2004; pp 63-78.
3. Fink-Gremmels, J. Mycotoxins: Their implications for human and animal health. Vet. Ourat. 1999, 21, 115-120.
4. Commission Regulation (EC). No. 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Off. J. Eur. Commun. 2006, 1, 364, 5-24.
5. Commission Regulation (EC). No. 1126/2007 of 28 September 2007 amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products. Off J. Eur. Commun. 2007, 1, 255, 14-17.
6. Zöllner, P.; Mayer-Helm, B. Trace mycotoxin analysis in complex biological and food matrices by liquid, chromatography-atmospheric pressure ionisation mass spectrometry. J. Chromatogr. A 2006, 1136, 123-169. (Pubitemid 44809126)
7. Krska, R.; Molinelli, A. Mycotoxin analysis: state-of-the-art and future trends. Anal. Bioanal. Chem. 2007, 387, 145-148. (Pubitemid 44956265)
8. Speijers, G. J.; Speijers, M. H. Combined toxic effects of mycotoxins. Toxicol. Lett. 2004, 153, 91-98.
9. Royer, D.; Humpf, H. U.; Guy, P. A. Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Food Addit. Contam. 2004, 21, 678-692.
10. Klötzel, M.; Lauber, U.; Humpf, H. U. A new solid phase extraction clean-up method for the determination of 12 type A. and B trichothecenes in cereals and cereal-based food by LC-MS/MS. Mol. Nutr. Food Res. 2006, 50, 261-269.
11. Biselli, S.; Hummert, C. Development of a multicomponent method for Fusarium toxins using LC-MS/MS and its application during a survey for the content of T-2 toxin and deoxynivalenol in various feed, and food samples. Food Addit. Contam. 2005, 22, 752-760. (Pubitemid 41236607)
12. Klötzel, M.; Gutsche, B.; Lauber, U.; Humpf, H. U. Determination of 12 type A and B trichothecenes in cereals by liquid chromatography-electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 2005, 53, 8904-8910. (Pubitemid 41735651)
13. Berthiller, F.; Schuhmacher, R.; Buttinger, G.; Krska, R. Rapid simultaneous determination of major type A- and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography-tandem mass spectrometry. J. Chroatogr. A 2005, 1062, 209-216. (Pubitemid 40044688)
14. Cavaliere, C.; D'Ascenzo, G.; Foglia, P.; Pastorini, E.; Samperi, R.; Laganà, A. Determination of type B trichothecenes and macrocyclic lactone mycotoxins in field contaminated maize. Food. Chem. 2005, 92, 559-568. (Pubitemid 40445517)
15. Ren, Y.; Zhang, Y.; Shao, S.; Cai, Z.; Feng, L.; Pan, H.; Wang, Z. Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry. J. Chromatogr. A 2007, 1143, 48-64. (Pubitemid 46209099)
16. Sulyok, M.; Berthiller, F.; Krska, R.; Schuhmacher, R. Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize. Rapid Commun. Mass Spectram. 2006, 20, 2649-2659. (Pubitemid 44497392)
17. Sulyok, M.; Krska, R.; Schuhmacher, R. A liquid chromatography/tandem, mass spectrometric multi-mycotoxin method for the quantification of 87 analytes and its application to semi-quantitative screening of moldy food samples. Anal. Bioanal. Chem. 2007, 389, 1505-1523. (Pubitemid 350023675)
18. Spanjer, M. C.; Rensen, P. M.; Scholten, J. M. LC-MS/MS multimethod for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs. Food Addit. Contam. 2008, 25, 472-489.
19. Beltrán, E.; Ibáñez, M.; Sancho, J. V.; Hernández, F. Determination of mycotoxins in different food commodities by ultra-high-pressure liquid chromatography coupled to triple quadrupole mass spectrometry. Rapid Commun. Mass Spectrom. 2009, 23, 1801-1809.
20. Herebian, D.; Zühike, S.; Lamshöft, M.; Spiteller, M. Multimycotoxin analysis in complex biological matrices using LC-ESI/MS: Experimental study using triple stage quadrupole and LTQOrbitrap. J. Sep. Sci. 2009, 32, 939-948.
21. Mol, H. G. J.; Plaza-Bolaños, P.; Zomer, P.; De Rijk, T. C.; Stolker, A. A. M.; Mulder, P. P. J. Toward a generic extraction method for simultaneous determination of pesticides, mycotoxins, plant toxins, and veterinary drugs in feed and food matrixes. Anal. Chem. 2008, 80, 9450-9459.
22. Frenich, A. G.; Vidal, J. L. M.; Romero-González, R.; Aguilera-Luiz, M. d. M. Simple and high-throughput method for the multimycotoxin analysis in cereals and related foods by ultra-high performance liquid chromatography/tandem mass spectrometry. Food Chem. 2009, 117, 705-712.
23. Anastassiades, M.; Lehotay, S. J.; Stajnbaher, D.; Schenck, F. J. Fast and easy multiresidue method employing acetonitrile extraction/partitioning and "dispersive solid-phase extraction" for the determination of pesticide residues in produce. J. AOAC Int. 2003, 86, 412-431.
24. Sospedra, I.; Blesa, J.; Soriano, J. M.; Manes, J. Use of the modified quick easy cheap effective rugged and safe sample preparation approach for the simultaneous analysis of type A- and B-trichothecenes in wheat flour. J. Chromatogr. A 2010, 1277, 1437-1440.
25. Zachariasova, M.; Lacina, O.; Malachova, A.; Kostelanska, M.; Poustka, J.; Godula, M.; Hajslova, J. Novel approaches in analysis of Fusarium mycotoxins in cereals employing ultra performance liquid chromatography coupled with high resolution mass spectrometry. Anal. Chim. Acta 2010, 662, 51-61.
26. Commission Decision 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and interpretation of results. Off. J. Eur. Commun. 2002, L221, 8-36.
27. Rodriguez, M.; Orescan, D. B. Confirmation and quantitation of selected sulfonylurea, imidazolinone, and sulfonamide herbicides in surface water using electrospray LC/MS. Anal. Chem. 1998, 70, 2710-2717. (Pubitemid 28353993)
28. Razzazi-Fazeli, E.; Böhm, J.; Luf, W. Determination of nivalenol and deoxynivalenol in wheat using liquid chromatography-mass spectrometry with negative ion atmospheric pressure chemical ionisation. J. Chromatogr. A 1999, 854, 45-55. (Pubitemid 29387304)
29. Di Mavungu, J. D.; Monbaliu, S.; Scippo, M. L.; Maghuin-Rogister, G.; Schneider, Y.-J.; Larondelle, Y.; Callebaut, A.; Robbens, J.; Van Peteghem, C.; De Sager, S. LC-MS/MS multi-analyte method for mycotoxin determination in food supplements. Food Addit. Contam. 2009, 26, 885-895.
30. Cavaliere, C.; Foglia, P.; Pastorini, E.; Samperi, R.; Lagana, A. Development of a multiresidue method for analysis of major Fusarium mycotoxins in corn meal using liquid chromatography/tandem mass spectrometry, Rapid Commun. Mass Spectrom. 2005, 19, 2085-2093. (Pubitemid 41026434)
31. Berger, U.; Oehme, M.; Kuhn, F. Quantitative determination and structure elucidation of type A- and B-trichothecenes by HPLC/ion trap multiple mass spectrometry. J. Agric. Food Chem. 1999, 47, 4240-4245.
32. Kokkonen, M. K.; Jestoi, M. N. A multi-compound LC-MS/MS method for the screening of mycotoxins in grains. Food Anal. Methods 2009, 2, 128-140.
33. -(3 3) Document No. SANCO/10684/2009. Method validation and quality control procedures pesticide residue analysis in food and feed; 2010; http://ec.europa.eu/food/plant/protection/resources/qualcontrol-en.pdf.
34. European Committee for Standardization (CEN). Draft standard prCEN/TR 16059. Food analysis-Performance criteria for single laboratory validated methods of analysis for the determination of mycotoxins. To be published.
35. Mottier, P.; Hammel, Y. A.; Gremaud, E.; Guy, P. A. Quantitative high-throughput analysis of 16 (fluoro)quinolones in honey using automated extraction by turbulent flow chromatography coupled to liquid chromatography-tandem mass spectrometry. J. Agric. Food Chem. 2008, 56, 35-43.
36. European Committee for Standardization (CEN). EN 15662:2008. Foods of plant origin - Determination of pesticide residues using GC-MS and/or LC-MS/MS following acetonitrile extraction/partitioning and clean-up by dispersive SPE-QuEChERS-method, 2008.