A mouse model to study infection against porcine circovirus type 2: Viral distribution and lesions in mouse

Virology Journal

Volumn 7, Issue , 2010, Pages

  Li, Jun ^a,b,c   Yuan, Xiaoyuan ^a,b   Zhang, Chaofan ^c   Miao, Lanfei ^c   Wu, Jiaqiang ^b   Shi, Jianli ^b   Xu, Shaojian ^b   Cui, Shangjin ^c   Wang, Jinbao ^a,b   Ai, Hongbin ^a  

^a SHANDONG NORMAL UNIVERSITY   (China)

^b SHANDONG PEANUT RESEARCH INSTITUTE   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BLOOD SAMPLING; CELL CULTURE; CELL DEATH; CIRCOVIRIDAE INFECTION; CIRCOVIRUS; CONTROLLED STUDY; EXPERIMENTAL MODEL; HISTOPATHOLOGY; INFECTION SENSITIVITY; INOCULATION; KUNMING MOUSE; LYMPH NODE; LYMPHOCYTE; MOUSE; MOUSE STRAIN; NONHUMAN; POLYMERASE CHAIN REACTION; PORCINE CIRCOVIRUS TYPE 2; SEROCONVERSION; THYMUS; VIRUS REPLICATION; ANIMAL; ANIMAL DISEASE; BLOOD; DISEASE MODEL; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; LUNG; PATHOLOGY; PHYSIOLOGY; SWINE DISEASE; VIROLOGY;

MUS; PORCINE CIRCOVIRUS 2; SUIDAE;

ANIMALS; ANTIBODIES, VIRAL; CIRCOVIRIDAE INFECTIONS; CIRCOVIRUS; DISEASE MODELS, ANIMAL; LUNG; LYMPH NODES; MICE; SWINE DISEASES;

EID: 77954547324     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-7-158     Document Type: Article

References (15)

1. Characterization of papovavirus and picornavirus-like particles in permanent pig kidney cell lines. I Tischer R Rasch G Tochtermann, Zentralbl Bakteriol Hyg A 1974 226 153 167
2. A very small porcine virus with circularsingle-stranded DNA. I Tischer H Gelderblom W Vettermann MA Koch, Nature 1982 295 64 66 10.1038/295064a0 7057875
3. Virus taxonomy at the XIth International Congress of Virology, Sydney, Australia. CR Pringle, Arch Virol 1999 144 2065 2070 10.1007/s007050050728 10550679
4. Reproduction of lesions of postweaning multisystemic wasting syndrome in gnotobiotic pigs. J Ellis S Krakowka M Lairmore D Haines A Bratanich E Clark G Allan C Konoby L Hassard B Meehan K Martin J Harding S Kennedy F McNeilly, J Vet Diagn Invest 1999 11 3 14 9925205
5. Cloned genomic DNA of type 2 porcine circovirus was infectious when injected directly into the liver and lymph nodes of pigs: characterization of clinical disease, virus distribution, and pathologic lesions. M Fenaux PG Halbur G Haqshenas, J Virol 2002 76 541 551 10.1128/JVI.76.2.541-551.2002 11752145
6. Post-weaning multisystemic wasting syndrome. EG Clark, Proc Annu Meet Am Assoc Swine Pract 1997 28 499 501
7. Eepidemic feature and restrain measures of immune inhibition diseases in pigs. HC Yang, China Animal Husbandry and Veterinary Medicine 2004 31 41 43
8. Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus. GM Allan S Kennedy F McNeilly JC Foster JA Ellis SJ Krakowka BM Meehan BM Adair, J Comp Pathol 1999 121 1 11 10.1053/jcpa.1998.0295 10373289
9. Experimental infection of colostrums deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication. GM Allan F McNeilly J Ellis S Krakowka B Meeham I McNair I Walker S Kennedy, Arch Virol 2000 145 2421 2429 10.1007/s007050070031 11205128
10. Porcine Circovirus type 2 (PCV2) causes apoptosis in experimentally inoculated BALB/c mice. M Kiupel WG Stevenson JE Galbreath A North H HogenEsch KS Mittal, BMC Veterinary Research 2005 1 7 10.1186/1746-6148-1-7 16259631
11. Clinical and pathological observations on pigs with postweaning multisystemic wasting syndrome. J Quintana J Segalés C Rosell M Calsamiglia GM Rodríguez-Arrioja F Chianini JM Folch J Maldonado M Doming M Canal J Plana-Durn, Vet Re 2001 149 357 361
12. Evidence for circovirus in cattle with respiratory disease and from aborted bovine fetuses. GP Nayar AL Hamel L Linn C Sachvie E Grudeski G Spearman, Can Vet J 1999 40 277 278 10200889
13. Experimental inoculation of porcine circoviruses type 1 (PCV1) and type 2 (PCV2) in rabbits and mice. J Quintana J Segalés M Calsamiglia M Domingo, Vet Res 2002 33 229 237 10.1051/vetres:2002011 12056474
14. Porcine circovirus causes congenital tremors type A-II proved by fulfilling Koch's postulates. RK Hines, PhD Diss University of Georgia, Athens, GA 1994
15. Molecular Cloning: A Laboratory Manual. J Sambrook DW Russell, Cold Spring Harbor Laboratory Press, New York 3 2001