Alcohol and HCV chronic infection are risk cofactors of type 2 diabetes mellitus for hepatocellular carcinoma in italy

International Journal of Environmental Research and Public Health

Volumn 7, Issue 4, 2010, Pages 1366-1378

  Balbi, Massimiliano ^a   Donadon, Valter ^a   Ghersetti, Michela ^a   Grazioli, Silvia ^a   della Valentina, Giovanni ^a   Gardenal, Rita ^a   Mas, Maria Dal ^a   Casarin, Pietro ^a   Zanette, Giorgio ^a   Miranda, Cesare ^a   Cimarosti, Paolo ^a  

^a Pordenone Hospital   (Italy)

Author keywords

Alcohol abuse; HCV infections; Hepatocellular carcinoma; Type 2 diabetes mellitus

Indexed keywords

ALCOHOL;

ADULT; AGED; ALCOHOL ABUSE; ALCOHOL CONSUMPTION; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; ITALY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; RISK FACTOR; CARCINOMA, HEPATOCELLULAR; COMPLICATION; DIABETES MELLITUS, TYPE 2; HEPATITIS C, CHRONIC; LIVER CIRRHOSIS, ALCOHOLIC; LIVER NEOPLASMS; MIDDLE AGED;

HEPATITIS C VIRUS;

AGED; CARCINOMA, HEPATOCELLULAR; DIABETES MELLITUS, TYPE 2; FEMALE; HEPATITIS C, CHRONIC; HUMANS; ITALY; LIVER CIRRHOSIS, ALCOHOLIC; LIVER NEOPLASMS; MALE; MIDDLE AGED; PREVALENCE;

EID: 77954547047     PISSN: None     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph7041366     Document Type: Article

References (44)

1. World Health Organization. Mortality database. Available online: http://www.who.int/whosis/whostat/EN_WHS08_Part1.pdf(accessed on 4 December 2008).
2. Armstrong, G.L.; Alter, M.J.; McQuillan, G.M.; Margolis, H.S. The past incidence of hepatitis C virus infection: implications for the future burden of chronic liver disease in the United States. Hepatology 2003, 1, 777-782.
3. Davila, J.A.; Morgan, R.O.; Shaib, Y.; McGlynn, K.A.; El-Serag, H.B. Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study. Gut 2005, 54, 533-539.
4. Metascreen Writing Committee; Bonadonna, R.C.; Cucinotta, D.; Fedele, D.; Riccardi, G.; Tiengo, A. The metabolic syndrome is a risk indicator of microvascular and macrovascular complications in diabetes: results from Metascreen, a multicenter diabetes clinic-based survey. Diabetes Care 2006, 29, 2701-2707.
5. Sloan, F.A.; Bethel, A.; Ruiz, D.; Shea, A.H.; Feinglos, M.N. The growing burden of diabetes mellitus in the US elderly population. Arch. Intern. Med. 2008, 168, 192-199.
6. Bugianesi, E.; Leone, N.; Vanni, E.; Marchesini, G.; Brunello, F.; Carucci, P.; Musso, A.; Polis, P.; Capussotti, L.; Salizzoni, M.; Rizzetto, M. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002, 123, 134-140.
7. Moscatiello, S.; Manini, R.; Marchesini, G. Diabetes and liver disease: an ominous association. Nutr. Metab. Cardiovasc. Dis. 2007, 17, 63-70.
8. El-Serag, H.B.; Richardson, P.A.; Everhart, J.E. The role of diabetes in hepatocellular carcinoma: a case-control study among United States veterans. Am. J. Gastroenterol. 2001, 96, 2462-2467.
9. Verlato, G.; Bonora, E.; Zoppini, G.; Muggeo, M. Mortality from site-specific malignancies in type 2 diabetic patients from Verona. Diabetes Care 2003, 26, 1047-1051.
10. Coughlin, S.S.; Calle, E.E.; Teras, L.R.; Petrelli, J.; Thun, M.J. Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am. J. Epidemiol. 2004, 159, 1160-1167.
11. El Serag, H.B.; Tran, T.; Everhart, J.E. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004, 126, 460-468.
12. Chen, C.L.; Yang, H.I.; Yang, W.S.; Liu, C.J.; Chen, P.J.; You, S.L.; Wang, L.Y.; Sun, C.A.; Lu, S.N.; Chen, D.S.; Chen, C.J. Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan. Gastroenterology 2008, 135, 111-121.
13. Inoue, M.; Iwasaki, M.; Otani, T.; Sasazuki, S.; Noda, M.; Tsugane, S. Diabetes mellitus and the risk of cancer: results from a large-scale population-based cohort study in Japan. Arch. Intern. Med. 2006, 166, 1871-1877.
14. Lai, M.S.; Hsieh, M.S.; Chiu, Y.H.; Chen, T.H.H. Type 2 diabetes and hepatocellular carcinoma: a cohort study in high prevalence area of hepatitis virus infection. Hepatology 2006, 43, 1295-1302.
15. Donadon, V.; Balbi, M.; Casarin, P.; Alberti, A. Association between hepatocellular carcinoma and type 2 diabetes mellitus in Italy: Potential role of insulin. World J. Gastroenterol. 2008, 14, 5695-700.
16. Hassan, M.M.; Hwang, L.Y.; Hatten, C.J.; Swaim, M.; Donghui, L.; Abbruzzese, J.L.; Beasley, P.; Patt, Y.Z. Risk factors for hepatocellular carcinoma. Synergism of alcohol with viral hepatitis and diabetes mellitus. Hepatology 2002, 36, 1206-1213.
17. Yuan, J.M.; Govindarajan, S.; Arakawa, K.; Yu, M. Synergism of alcohol, diabetes and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the US. Cancer 2004, 101, 1009-1017.
18. Llovet, J.M.; Beaugrand, M. Hepatocellular carcinoma: present status and future prospects. J. Hepato. 2003, 38, S136-S149.
19. De Paschale, M.; Biagiotti, S.; Chianese, R. Variazione nel tempo della prevalenza dei marcatori dell'epatite B in donatori di sangue. La trasfusione del sangue 2001, 46, 335-340.
20. Pilotto, L.; Gaggioli, A.; Lo Noce, C.; Dima, F.; Palmieri, L.; Uguccioni, M.; Pede, S.; Giampaoli, S.; Vanuzzo, D. Diabetes in Italy: a public health problem. Ital. Heart. J. Suppl. 2004, 5, 480-486.
21. Bellentani, S.; Miglioli, L.; Bedogni, G; Crocè, L.S; Tiribelli, C. Epidemiology of hepatitis C virus infection. Minerva Gastroenterol. Dietol. 2005, 51, 15-29.
22. Bellentani, S.; Tiribelli, C; Saccoccio, G; Sodde, M; Fratti, M.; De Martin, C; Cristianini, G. Prevalence of chronic liver disease in the general population of Northern Italy: The dionysos study. Hepatology 1994, 20, 1442-1449.
23. National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1979, 28, 1039-1057.
24. American Diabetes Association. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003, 26, S5-S20.
25. Corrao, G.; Lepore, A.R.; Torchio, P.; Valenti, M.; Galatola, G.; D'amicis, A.; Arico, S.; di Orio, F. The effect of drinking coffee and smoking cigarettes on the risk of cirrhosis associated with alcohol consumption. A case-control study. Provincial group for the study of chronic liver disease. Eur. J. Epidemiol. 1994, 10, 657-664.
26. Rothman, K.J. The estimation of synergy or antagonism. Am. J. Epidemiol. 1976, 103, 506-511.
27. McKeown-Eyssen, G. Epidemiology of colorectal cancer revisited: are serum triglycerides and/or plasma glucose associated with risk? Cancer Epidemiol. Biomarkers. Prev. 1994, 3, 687-695.
28. Giovannucci, E. Insulin and colon cancer. Cancer Causes Control. 1995, 6, 164-179.
29. Giovannucci, E. Nutrition, insulin, insulin-like growth factors and cancer. Horm. Metab. Res. 2003, 35, 694-704.
30. Balkau, B.; Kahn, H.S.; Courbon, D; Eschwege, E; Ducimetiere, P. Hyperinsulinemia predicts fatal liver cancer but is inversely associated with fatal cancer at some other sites. Diabetes Care 2001, 24, 843-849.
31. Carlsson, S; Hammar, N; Grill, V. Alcohol consumption and type 2 diabetes. Diabetologia 2005, 48, 1051-1054.
32. Rosen, P; Nawroth, P.P; King, G; Moller, W; Tritschler, H.J; Packer, L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab. Res. Rev. 2001, 17, 189-212.
33. Kar, M.; Chakraborti, A.S. Release of iron from haemoglobin a possible source of free radicals in diabetes mellitus. Indian J. Exp. Boil. 1999, 37, 190-192.
34. Ford, E.S.; Cogswell, M.E. Diabetes and serum ferritin concentration among US adults. Diabetes Care 1999, 22, 1978-1983.
35. Oberley, L.W. Free radicals and diabetes. Free Radic. Boil. Med. 1988, 5, 113-124.
36. Gillery, P.; Monboisse, J.C; Maquart, F.X; Borel, J.P. Does oxygen free radical increased formation explain long term complications of diabetes mellitus? Med. Hypotheses 1989, 29, 47-50.
37. Batey, R.G.; Burns, T; Benson, R.J.; Byth, K. Alcohol consumption and risk for cirrhosis. Med. J. Aust. 1992, 156, 413-416.
38. Lieber, C.S.; Seitz, H.K; Garro, A.J;, Worner, T.M. Alcohol related disease and carcinogenesis. Cancer Res. 1979, 39, 2863-2886.
39. Lieber, C.S. Mechanism of ethanol induced hepatic injury. Pharmacol. Ther. 1990, 46, 1-46.
40. McKillop, I.; Schrum, L.W. Alcohol and liver cancer. Alcohol 2005, 35, 195-203.
41. Petersen, D.R. Alcohol, iron-associated oxidative stress and cancer. Alcohol 2005, 35, 243-249.
42. Wang, X.D. Alcohol, vitamin A and cancer. Alcohol 2005, 35, 251-258.
43. De Marco, R.; Locatelli, F; Zoppini, G; Verlato, G; Bonora, E; Muggeo, M. Cause-specific mortality in type 2 diabetes: The Verona diabetes study. Diabetes Care 1999, 22, 756-761.
44. Tolman, K.G; Fonseca, V; Dalpiaz, A; Tan, M.H. Spectrum of liver disease in type 2 diabetes and management of patients with diabetes and liver disease. Diabetes Care 2007, 30, 734-743.