Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of a case-control study

BMC Medical Genetics

Volumn 11, Issue 1, 2010, Pages

  Teeuw, Marieke E ^a   Henneman, Lidewij ^a   Bochdanovits, Zoltan ^a   Heutink, Peter ^a   Kuik, Dirk J ^a   Cornel, Martina C ^a   ten Kate, Leo P ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; AUTOSOMAL RECESSIVE INHERITANCE; CASE CONTROL STUDY; CONSANGUINITY; CONTROLLED STUDY; FAMILY HISTORY; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; PARENT; PEDIGREE; PROGENY; RELATIVE; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; CHILD; CHROMOSOME DISORDER; FEMALE; GENETIC VARIABILITY; GENETICS; MALE; MORTALITY; PREVALENCE; RECESSIVE GENE; REFERENCE VALUE; STATISTICS;

CHILD; CHROMOSOME DISORDERS; CONSANGUINITY; DNA; FEMALE; GENES, RECESSIVE; GENETIC VARIATION; HUMANS; MALE; PARENTS; PEDIGREE; PREVALENCE; REFERENCE VALUES; RISK ASSESSMENT; STOCHASTIC PROCESSES;

EID: 77954546959     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-11-113     Document Type: Article

References (13)

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