Epigallocatechin-3-gallate inhibits mast cell degranulation, leukotriene C4 secretion, and calcium influx via mitochondrial calcium dysfunction

Free Radical Biology and Medicine

Volumn 49, Issue 4, 2010, Pages 632-640

  Inoue, Toshio ^a   Suzuki, Yoshihiro ^a   Ra, Chisei ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

Antigen; Ca2+; EGCG; Mast cell; Mtochondria; ROS

Indexed keywords

CALCIUM; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CARDIOLIPIN; EPICATECHIN; EPIGALLOCATECHIN GALLATE; LEUKOTRIENE C4; REACTIVE OXYGEN METABOLITE;

ALLERGY; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CHANNEL GATING; CONTROLLED STUDY; DRUG STRUCTURE; INHIBITION KINETICS; LIPID OXIDATION; MAST CELL DEGRANULATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT;

ANIMALS; CALCIUM; CATECHIN; LEUKOTRIENE C4; MAST CELLS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; RATS; REACTIVE OXYGEN SPECIES;

ANIMALIA;

EID: 77954543185     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.05.015     Document Type: Article

References (45)

1. Graham H.N. Green tea composition, consumption, and polyphenol chemistry. Prev. Med. 1992, 21:334-350.
2. Salah N., Miller N.J., Paganga G., Tijburg L., Bolwell G.P., Rice-Evans C. Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidans. Arch. Biochem. Biophys. 1995, 322:339-346.
3. Rice-Evans C. Plant polyphenols: free radical scavengers or chain-breaking antioxidant?. Biochem. Soc. Symp. 1995, 61:103-116.
4. Gao Y.T., McLaughlin J.K., Blot W.J., Ji B.T., Dai Q., Fraumeni J.F. Reduced risk of esophageal cancer associated with green tea consumption. J. Natl Cancer Inst. 1994, 86:855-858.
5. Mandel S., Youdim M.B. Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases. Free Radic. Biol. Med. 2004, 37:304-317.
6. Zaveri N.T. Green tea and its polyphenolic catechins: medicinal uses in cancer and noncancer applications. Life Sci. 2006, 78:2073-2080.
7. Shimizu M., Weinstein I.B. Modulation of signal transduction by tea catechins and related phytochemicals. Mutat. Res. 2005, 591:147-160.
8. Khan N., Afaq F., Saleem M., Ahmad N., Mukhtar H. Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res. 2006, 66:2500-2505.
9. Patra S.K., Rizzi F., Silva A., Rugina D.O., Bettuzzi S. Molecular targets of (-)-epigallocatechin-3-gallate (EGCG): specificity and interaction with membrane lipid rafts. J. Physiol. Pharmacol. 2008, 59(Suppl. 9):217-235.
10. Tachibana H. Molecular basis for cancer chemoprevention by green tea polyphenol EGCG. Forum Nutr. 2009, 61:156-169.
11. Shimizu M., Shirakami Y., Moriwaki H. Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG. Int. J. Mol. Sci. 2008, 9:1034-1049.
12. Orrenius S., Gogvadze V., Zhivotovsky B. Mitochondrial oxidative stress: implications for cell death. Annu. Rev. Pharmacol. Toxicol. 2007, 47:143-183.
13. Suzuki M., Yoshino K., Maeda-Yamamoto M., Miyase T., Sano M. Inhibitory effects of tea catechins and O-methylated derivatives of (-)-epigallocatechin-3-O-gallate on mouse type IV allergy. J. Agric. Food Chem. 2000, 48:5649-5653.
14. Kinet J.P. The high-affinity IgE receptor (FcεRI): from physiology to pathology. Annu. Rev. Immunol. 1999, 17:931-972.
15. Matsuo N., Yamada K., Shoji K., Mori M., Sugano M. Effect of tea polyphenols on histamine release from rat basophilic leukemia (RBL-2H3) cells: the structure-inhibitory activity relationship. Allergy 1997, 52:58-64.
16. Yamashita K., Suzuki Y., Matsui T., Yoshimaru T., Yamaki M., Suzuki-Karasaki M., Hayakawa S., Shimizu K. Epigallocatechin gallate inhibits histamine release from rat basophilic leukemia (RBL-2H3) cells: role of tyrosine phosphorylatipon pathway. Biochem. Biophys. Res. Commun. 2000, 274:603-608.
17. Nanjo F., Goto K., Seto R., Suzuki M., Sakai M., Hara Y. Scavenging effects of tea catechins and their derivatives on 1, 1-diphenyl-2-picrylhydrazyl radical. Free Radic. Biol. Med. 1996, 21:895-902.
18. Suzuki Y., Yoshimaru T., Matsui T., Inoue T., Niide O., Nunomura S., Ra C. FcεRI signaling of mast cells activates intracellular psoduction of hydrogen peroxide: role in the regulation of calcium signals. J. Immunol. 2003, 171:6119-6127.
19. 2+-dependent mast cell death induced by Ag (I) via cardiolipin oxidation and ATP depletion. J. Leukoc. Biol. 2009, 86:167-179.
20. 2+ dependence of mast cell degranulation. J. Leukoc. Biol. 2006, 79:508-518.
21. Hajnóczky G., Robb-Gaspers L.D., Seitz M.B., Thomas A.P. Decoding of cytosolic calcium oscillations in the mitochondria. Cell 1995, 82:415-424.
22. Inoue T., Suzuki Y., Yoshimaru T., Ra C. Reactive oxygen species produced up- or downstream of calcium influx regulate proinflammatory mediator release from mast cells: role of NADPH oxidase and mitochondria. Biochim. Biophys. Acta 2008, 1783:789-802.
23. 4 secretion. J. Biol. Chem. 2004, 279:29994-29999.
24. Zweifach A., Lewis R.S. Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes. J. Gen. Physiol. 1996, 107:597-610.
25. Parekh A.B., Fleig A., Penner R. The store-operated calcium current I (CRAC): nonlinear activation by InsP3 and dissociation from calcium release. Cell 1997, 89:973-980.
26. 2+ uptake. EMBO J. 2002, 21:6744-6754.
27. Suzuki Y., Yoshimaru T., Inoue T., Nunomura S., Ra C. The high-affinity immunoglobulin E receptor (FcεRI) regulates mitochondrial calcium uptake and a dihydropyridine receptor-mediated calcium influx in mast cells: role of the FcεRIβ chain immunoreceptor tyrosine-based activation motif. Biochem. Pharmacol. 2008, 75:1492-1503.
28. 2+ influx and mast cell activation: role of a nitric oxide synthase-independent pathway. J. Leukoc. Biol. 2009, 86:1365-1375.
29. Suzuki Y., Yoshimaru T., Inoue T., Niide O., Ra C. Role of oxidants in mast cell activation. Chem. Immunol. Allergy 2005, 87:32-42.
30. 2+ channel activity. Mol. Immunol. 2009, 46:2200-2209.
31. Robinson K.M., Janes M.S., Pehar M., Monette J.S., Ross M.F., Hagen T.M., Murphy M.P., Beckman J.S. Selective fluorescent imaging of superoxide in vivo using ethidium-based probes. Proc. Natl Acad. Sci. U. S. A. 2006, 103:15038-15043.
32. Mukhopadhyay P., Rajesh M., Kashiwaya Y., Haskó G., Pacher P. Simple quantitative detection of mitochondrial superoxide production in live cells. Biochem. Biophys. Res. Commun. 2007, 358:203-208.
33. Petit J.M., Maftah A., Ratinaud M.H., Julien R. 10N-nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria. Eur. J. Biochem. 1992, 209:267-273.
34. 2+ mediated oxidative modification of low density lipoprotein. Biol. Pharm. Bull. 1994, 17:1567-1572.
35. Kondo K., Kurihara M., Miyata N., Suzuki T., Toyoda M. Scavenging mechanism of (-)-epigallocatechin gallate and (-)-epigallocatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action. Free Radic. Biol. Med. 1999, 27:855-863.
36. Sang S., Hou Z., Lambert J.D., Yang C.S. Redox properties of tea polyphenols and related biological activities. Antioxid. Redox Signal. 2005, 7:1704-1714.
37. Parekh A.B., Penner R. Store depletion and calcium influx. Physiol. Rev. 1997, 77:901-930.
38. Parekh A.B., Putney J.W. Store-operated calcium channels. Physiol. Rev. 2005, 85:757-810.
39. Hoth M., Penner R. Depletion of intracellular calcium stores activates a calcium current in mast cells. Nature 1992, 355:353-356.
40. Vig M., Kinet J.P. Calcium signaling in immune cells. Nat. Immunol. 2009, 10:21-27.
41. Baba Y., Nishida K., Fujii Y., Hirano T., Hikida M., Kurosaki T. Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses. Nat. Immunol. 2009, 9:81-88.
42. 2+ uptake. EMBO J. 2002, 21:6744-6754.
43. 2+ channels. Mol. Immunol. 2009, 46:1267-1277.
44. 2+ influx. Clin. Immunol. 2009, 13:146-156.
45. 2+ signaling, cell activation and cell survival in immune cells. Mol. Immunol. 2010, 47:640-648.