High expression and activity of ecto-5'-nucleotidase/CD73 in the male murine reproductive tract

Histochemistry and Cell Biology

Volumn 133, Issue 6, 2010, Pages 659-668

  Martín Satué, Mireia ^a,b   Lavoie, Elise G ^a   Fausther, Michel ^a   Lecka, Joanna ^a   Aliagas, Elisabet ^b   Kukulski, Filip ^a   Sévigny, Jean ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Adenosine; ATP; CD73; Ecto 5' nucleotidase; Epididymis; NTPDase; P1 and P2 receptors; Sperm

Indexed keywords

5' NUCLEOTIDASE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; NUCLEOTIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; EPIDIDYMIS; EXOCRINE GLAND; GENITAL SYSTEM; HYDROLYSIS; IMMUNOLOGICAL TECHNIQUE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; SOMATIC CELL; SPERM; TESTIS;

5'-NUCLEOTIDASE; ANIMALS; BLOTTING, WESTERN; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENITALIA, MALE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; TESTIS; VAS DEFERENS;

MAMMALIA; MURINAE;

EID: 77954542696     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-010-0704-z     Document Type: Article

References (42)

1. Adeoya-Osiguwa SA, Fraser LR (2002) Capacitation state-dependent changes in adenosine receptors and their regulation of adenylyl cyclase/cAMP. Mol Reprod Dev 63(2):245-255
2. Aliagas E, Torrejón-Escribano B, Lavoie EG, de Aranda IG, Sévigny J, Solsona C, Martín-Satué M (2010) Changes in expression and activity levels of ecto-50-nucleotidase/CD73 along the mouse female estrous cycle. Acta Physiol (Oxf) Feb 5. doi: 10.1111/j.1748-1716.2010. 02095.x (Epub ahead of print)
3. Antonio LS, Costa RR, Gomes MD, Varanda WA (2009) Mouse Leydig cells express multiple P2X receptor subunits. Purinergic Signal 3:277-287
4. Banks FC, Calvert RC, Burnstock G (2009) Changing P2X receptor localization on maturing sperm in the epididymides of mice, hamsters, rats, and humans: a preliminary study. Fertil and Steril. doi:10.1016/j.fertnstert.2009. 02.061
5. Baykov AA, Evtushenko OA, Avaeva SM (1988) A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Anal Biochem 171:266-270
6. Belleannee C, Da Silva N, Shum W, Breton S (2009) Role of luminal ATP and adenosine in V-ATPase activation. Biol Reprod 81:21
7. Benarroch EE (2008) Adenosine and its receptors: multiple modulatory functions and potential therapeutic targets for neurologic disease. Neurology 70:231-236
8. Boeynaems JM, Communi D, Gonzalez NS, Robaye B (2005) Overview of the P2 receptors. Semin Thromb Hemost 31:139-149
9. Braun N, Sévigny J, Mishra SK, Robson SC, Barth SW, Gerstberger R, Hammer K, Zimmermann H (2003) Expression of the ecto- ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. Eur J Neurosci 17:1355-1364
10. Burnstock G (2006) Purinergic signalling. Br J Pharmacol 147(Suppl 1):S172-S181
11. Burnstock G (2007) Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 87:659-797
12. Carlin RW, Lee JH, Marcus DC, Schultz BD (2003) Adenosine stimulates anion secretion across cultured and native adult human vas deferens epithelia. Biol Reprod 68:1027-1034
13. Colgan SP, Eltzschig HK, Eckle T, Thompson LF (2006) Physiological roles for ecto-50-nucleotidase (CD73). Purinergic Signal 2(2):351-360
14. Diniz C, Leal S, Goncalves J (2003) Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens. Eur J Pharmacol 460:191-199
15. Fausther M, Lecka J, Kukulski F, Lévesque SA, Pelletier J, Zimmermann H, Dranoff JA, Sévigny J (2007) Cloning, purification, and identification of the liver canalicular ecto- ATPase as NTPDase8. Am J Physiol Gastrointest Liver Physiol 292:G785-G795
16. Foresta C, Rossato M, Di Virgilio F (1992) Extracellular ATP is a trigger for the acrosome reaction in human spermatozoa. J Biol Chem 267(27):19443-19447
17. Foresta C, Rossato M, Nogara A, Gottardello F, Bordon P, Di Virgilio F (1996) Role of P2-purinergic receptors in rat Leydig cell steroidogenesis. Biochem J 320:499-504
18. Fraser LR (2008) The role of small molecules in sperm capacitation. Theriogenology 70:1356-1359
19. Fredholm BB, Jzerman AP, Jacobson KA, Klotz KN, Linden J (2001) International Union of Pharmacology XXV nomenclature and classification of adenosine receptors. Pharmacol Rev 53:527-552
20. Glass R, Bardini M, Robson T, Burnstock G (2001) Expression of nucleotide P2X receptor subtypes during spermatogenesis in the adult rat testis. Cells Tissues Organs 169(4):377-387
21. Kauffenstein G, Drouin A, Thorin-Trescases N, Bachelard H, Robaye B, D'Orléans-Juste P, Marceau F, Thorin E, Sévigny J (2010) NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse. Cardiovasc Res 1;85(1):204-213
22. Koszalka P, Ozüyaman B, Huo Y, Zernecke A, Flögel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sévigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, Ley K, Zimmermann H, Gödecke A, Schrader J (2004) Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circ Res 95(8):814-821
23. Kukulski F, Lévesque SA, Lavoie EG, Lecka J, Bigonnesse F, Knowles AF, Robson SC, Kirley TL, Sévigny J (2005) Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8. Purinergic Signal 1:193-204
24. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
25. Lazarowski ER, Tarran R, Grubb BR, van Heusden CA, Okada S, Boucher RC (2004) Nucleotide release provides a mechanism for airway surface liquid homeostasis. J Biol Chem 279(35):36855-36864
26. Levitt B, Head RJ, Westfall DP (1984) High-pressure liquid chromatographic-fluorometric detection of adenosine and adenine nucleotides: application to endogenous content and electrically induced release of adenyl purines in guinea pig vas deferens. Anal Biochem 137(1):93-100
27. Loir M (2001) Adenosine receptor-adenylate cyclase system in the trout testis: involvement in the regulation of germ cell proliferation. Mol Reprod Dev 58(3):307-317
28. Martín-Satué M, Lavoie EG, Pelletier J, Fausther M, Csizmadia E, Guckelberger O, Robson SC, Sévigny J (2009) Localization of plasma membrane bound NTPDases in the murine reproductive tract. Histochem Cell Biol 131:615-628
29. Minelli A, Allegrucci C, Piomboni P, Mannucci R, Lluis C, Franco R (2000) Immunolocalization of A1 adenosine receptors in mammalian spermatozoa. J Histochem Cytochem 48:1163-1171
30. Minelli A, Liguori L, Bellazza I, Mannucci R, Johansson B, Fredholm BB (2004) Involvement of A1 adenosine receptors in the acquisition of fertilizing capacity. J Androl 25:286-292
31. Minelli A, Bellezza I, Collodel G, Fredholm BB (2008) Promiscuous coupling and involvement of protein kinase C and extracellular signal-regulated kinase 1/2 in the adenosine A1 receptor signalling in mammalian spermatozoa. Biochem Pharmacol 75:931-941
32. Monks NJ, Fraser LR (1988) Enzymes of adenosine metabolism in mouse sperm suspensions. J Reprod Fertil 83:389-399
33. Queiroz G, Talaia C, Goncalves J (2003a) ATP modulates noradrenaline release by activation of inhibitory P2Y receptors and facilitatory P2X receptors in the rat vas deferens. J Pharmacol Exp Ther 307:809-815
34. Queiroz G, Talaia C, Gonçalves J (2003b) Adenosine A2A receptormediated facilitation of noradrenaline release involves protein kinase C activation and attenuation of presynaptic inhibitory receptor-mediated effects in the rat vas deferens. J Neurochem 85(3):740-748
35. Resta R, Hooker SW, Hansen KR, Laurent AB, Park JL, Blackburn MR, Knudsen TB, Thompson LF (1993) Murine ecto-5'- nucleotidase (CD73): cDNA cloning and tissue distribution. Gene 133(2):171-177
36. Rivkees SA (1994) Localization and characterization of adenosine receptor expression in rat testis. Endocrinology 135:2307-2313
37. Robson SC, Sévigny J, Zimmermann H (2006) The E-NTPDase family of ectonucleotidases: structure function relationships and pathophysiological significance. Purinergic Signal 2:409-430
38. Rodriguez-Miranda E, Buffone MG, Edwards SE, Ord TS, Lin K, Sammel MD, Gerton GL, Moss SB, Williams CJ (2008) Extracellular adenosine 5'-triphosphate alters motility and improves the fertilizing capability of mouse sperm. Biol Reprod 79:164-171
39. Schuh SM, Hille B, Babcock DF (2007) Adenosine and catecholamine agonists speed the flagellar beat of mammalian sperm by a non-receptor-mediated mechanism. Biol Reprod 77:960-969
40. Yegutkin GG (2008) Nucleotide- and nucleoside-converting ectoenzymes: important modulators of purinergic signalling cascade. Biochim Biophys Acta 1783:673-694
41. Zhou WL, Zuo WL, Ruan YC, Wang Z, Du JY, Xiong Y, Chan HC (2007) The role of extracellular ATP in the male reproductive tract. Sheng Li Xue Bao 59:487-494
42. Zimmermann H (2001) Ectonucleotidases: some recent developments and a note on nomenclature. Drug Dev Res 52:44-56