Association between the A1 allele of the DRD2 gene and reduced verbal abilities in adolescence and early adulthood

Journal of Neural Transmission

Volumn 117, Issue 7, 2010, Pages 827-830

  Beaver, Kevin M ^a   Delisi, Matt ^b   Vaughn, Michael G ^c   Wright, John Paul ^d  

^a FLORIDA STATE UNIVERSITY   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c SAINT LOUIS UNIVERSITY   (United States)

^d UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Add Health; Dopamine; DRD2; Verbal skills

Indexed keywords

ADOLESCENT; ADULT; ALLELE; ARTICLE; CAUCASIAN; DNA POLYMORPHISM; DOPAMINE 2 RECEPTOR GENE; FEMALE; GENE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; VERBAL COMMUNICATION; DNA SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; LANGUAGE; LANGUAGE TEST; LEARNING; LONGITUDINAL STUDY; UNITED STATES; YOUNG ADULT;

ADOLESCENT; ALLELES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; HUMANS; LANGUAGE; LANGUAGE TESTS; LONGITUDINAL STUDIES; MALE; POLYMORPHISM, GENETIC; RECEPTORS, DOPAMINE D2; SEQUENCE ANALYSIS, DNA; UNITED STATES; VERBAL LEARNING; YOUNG ADULT;

DOPAMINE 2 RECEPTOR;

EID: 77954539423     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-010-0421-8     Document Type: Article

References (19)

1. TP Alloway SE Gathercole SJ Pickering 2006 Verbal and visuospatial short-term and working memory in children: are they separable? Child Dev 77 1698 1716 10.1111/j.1467-8624.2006.00968.x 17107455 (Pubitemid 44730036)
2. D Ball L Hill TC Eley MJ Chorney K Chorney LA Thompson, et al. 1998 Dopamine markers and general cognitive ability Neuroreport 9 347 349 10.1097/00001756-199801260-00031 1:CAS:528:DyaK1cXhtFCgurs%3D 9507981
3. SM Berman EP Noble 1995 Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele Behav Genet 25 45 58 10.1007/BF02197241 1:STN:280:DyaK2M3nsFWrtg%3D%3D 7755518
4. IJ Deary W Johnson LM Houlihan 2009 Genetic foundations of human intelligence Hum Genet 126 215 232 10.1007/s00439-009-0655-4 19294424
5. BC Haberstick A Smolen 2004 Genotyping of three single nucleotide polymorphisms following whole genome preamplification of DNA collected from buccal cells Behav Genet 34 541 547 10.1023/B:BEGE.0000038492.50446.25 15319577 (Pubitemid 39178767)
6. N Harlaar LM Butcher E Meaburn P Sham IW Craig R Plomin 2005 A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds J Child Psychol Psychiatry 46 1097 1107 10.1111/j.1469-7610.2005.01515.x 16178934 (Pubitemid 44201557)
7. Harris KM, Florey F, Tabor J, Bearman PS, Jones J, Udry JR (2003) The national longitudinal study of adolescent health: research design [www document]. http://www.cpc.unc.edu/projects/addhealth/design
8. KM Harris CT Halpern A Smolen BC Haberstick 2006 The national longitudinal study of adolescent health (Add Health) twin data Twin Res Hum Genet 9 988 997 10.1375/twin.9.6.988 17254442
9. HW Moises RM Frieboes P Spelzhaus L Yang, et al. 2001 No association between dopamine D2 receptor gene (DRD2) and human intelligence J Neural Trans 108 115 121 10.1007/s007020170102 1:CAS:528:DC%2BD3MXivVKrsrg%3D (Pubitemid 32692618)
10. 2 dopamine receptor gene with receptor binding characteristics in alcoholism Arch Gen Psychiatry 48 648 654 1:STN:280:DyaK3M3pvVyntg%3D%3D 2069496
11. EP Noble LA Gottschalk JH Fallon T Ritchie JC Wu 1997 D2 dopamine polymorphism and brain regional glucose metabolism Am J Med Genet 74 162 166 10.1002/(SICI)1096-8628(19970418)74:2<162::AID-AJMG9>3.0.CO;2-W 1:STN:280:DyaK2s3nsF2mtw%3D%3D 9129716 (Pubitemid 27187645)
12. SA Petrill R Plomin GE McClearn DL Smith S Vignetti, et al. 1997 No association between general cognitive ability and the A1 allele of the D2 dopamine receptor gene Behav Genet 27 29 31 10.1023/A:1025659124405 1:STN:280:DyaK2s3ptV2itw%3D%3D 9145541
13. R Plomin 1999 Genetics and general cognitive ability Nature 402 C25 C29 10.1038/35011520 1:CAS:528:DyaK1MXnslKmsrs%3D 10591222
14. R Plomin Y Kovas 2005 Generalist genes and learning disabilities Psychol Bull 131 592 617 10.1037/0033-2909.131.4.592 16060804 (Pubitemid 41168498)
15. R Plomin FM Spinath 2002 Genetics and general cognitive ability (g) Trends Cogn Sci 6 169 176 10.1016/S1364-6613(00)01853-2 11912040 (Pubitemid 34242701)
16. R Plomin FM Spinath 2004 Intelligence: genetics, genes, and genomics J Pers Soc Psychol 86 112 129 10.1037/0022-3514.86.1.112 14717631 (Pubitemid 38142814)
17. MD Resnick PS Bearman RW Blum KE Bauman KM Harris J Jones J Tabor T Beuhring RE Sieving M Shew M Ireland LH Bearinger JR Udry 1997 Protecting adolescents from harm: findings from the national longitudinal study of adolescent health JAMA 278 823 832 10.1001/jama.278.10.823 1:STN:280: DyaK2svjvVaitw%3D%3D 9293990
18. DC Rowe KC Jacobson EJCG Van den Oord 1999 Genetic and environmental influences on vocabulary IQ: parental education level as moderator Child Dev 70 1151 1162 10.1111/1467-8624.00084 1:STN:280:DC%2BD3c%2FhtlKlsw%3D%3D 10546338
19. Udry JR (2003) The national longitudinal study of adolescent health (Add Health), waves I and II, 1994-1996; Wave III, 2001-2002 [machine-readable data file and documentation]. Carolina Population Center, University of North Carolina, Chapel Hill