-
1
-
-
0010203413
-
Interactions between bcl-2 and the IGF system control apoptosis in the developing mouse brain
-
Baker NL, Carlo Russo V, Bernard O, D'Ercole AJ, Werther GA (1999) Interactions between bcl-2 and the IGF system control apoptosis in the developing mouse brain. Brain Res Dev Brain Res 118:109-118
-
(1999)
Brain Res Dev Brain Res
, vol.118
, pp. 109-118
-
-
Baker, N.L.1
Carlo Russo, V.2
Bernard, O.3
D'Ercole, A.J.4
Werther, G.A.5
-
2
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn LI, Miller TM, Cleveland DW (2004) Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 27:723-749
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
3
-
-
33745573660
-
Control of microglial neurotoxicity by the fractalkine receptor
-
Cardona AE, Pioro EP, Sasse ME, Kostenko V, Cardona SM, Dijkstra IM, Huang D, Kidd G, Dombrowski S, Dutta R et al (2006) Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci 9:917-924
-
(2006)
Nat Neurosci
, vol.9
, pp. 917-924
-
-
Cardona, A.E.1
Pioro, E.P.2
Sasse, M.E.3
Kostenko, V.4
Cardona, S.M.5
Dijkstra, I.M.6
Huang, D.7
Kidd, G.8
Dombrowski, S.9
Dutta, R.10
-
4
-
-
57749100302
-
Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
-
Chattopadhyay M, Durazo A, Sohn SH, Strong CD, Gralla EB, Whitelegge JP, Valentine JS (2008) Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. Proc Natl Acad Sci USA 105:18663-18668
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18663-18668
-
-
Chattopadhyay, M.1
Durazo, A.2
Sohn, S.H.3
Strong, C.D.4
Gralla, E.B.5
Whitelegge, J.P.6
Valentine, J.S.7
-
5
-
-
14344256204
-
Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice
-
Crochemore C, Pena-Altamira E, Virgili M, Monti B, Contestabile A (2005) Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice. Neurochem Int 46:357-368
-
(2005)
Neurochem Int
, vol.46
, pp. 357-368
-
-
Crochemore, C.1
Pena-Altamira, E.2
Virgili, M.3
Monti, B.4
Contestabile, A.5
-
6
-
-
33646466296
-
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria
-
Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH et al (2006) Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria. Proc Natl Acad Sci USA 103:7142-7147
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7142-7147
-
-
Deng, H.X.1
Shi, Y.2
Furukawa, Y.3
Zhai, H.4
Fu, R.5
Liu, E.6
Gorrie, G.H.7
Khan, M.S.8
Hung, W.Y.9
Bigio, E.H.10
-
7
-
-
70350075024
-
Genetics of motor neuron disorders: New insights into pathogenic mechanisms
-
Dion PA, Daoud H, Rouleau GA (2009) Genetics of motor neuron disorders: new insights into pathogenic mechanisms. Nat Rev Genet 10:769-782
-
(2009)
Nat Rev Genet
, vol.10
, pp. 769-782
-
-
Dion, P.A.1
Daoud, H.2
Rouleau, G.A.3
-
8
-
-
34250177650
-
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
-
Ezzi SA, Urushitani M, Julien JP (2007) Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. J Neurochem 102:170-178
-
(2007)
J Neurochem
, vol.102
, pp. 170-178
-
-
Ezzi, S.A.1
Urushitani, M.2
Julien, J.P.3
-
9
-
-
34447294839
-
Gene expression analysis of the murine model of amyotrophic lateral sclerosis: Studies of the Leu126- delTT mutation in SOD1
-
Fukada Y, Yasui K, Kitayama M, Doi K, Nakano T, Watanabe Y, Nakashima K (2007) Gene expression analysis of the murine model of amyotrophic lateral sclerosis: studies of the Leu126- delTT mutation in SOD1. Brain Res 1160:1-10
-
(2007)
Brain Res
, vol.1160
, pp. 1-10
-
-
Fukada, Y.1
Yasui, K.2
Kitayama, M.3
Doi, K.4
Nakano, T.5
Watanabe, Y.6
Nakashima, K.7
-
10
-
-
0028125281
-
Transgenic-mouse model of amyotrophic lateral sclerosis
-
Gurney ME (1994) Transgenic-mouse model of amyotrophic lateral sclerosis. N Engl J Med 331:1721-1722
-
(1994)
N Engl J Med
, vol.331
, pp. 1721-1722
-
-
Gurney, M.E.1
-
11
-
-
0037734370
-
Mutations in dynein link motor neuron degeneration to defects in retrograde transport
-
New York, NY
-
Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S et al (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (New York, NY) 300:808-812
-
(2003)
Science
, vol.300
, pp. 808-812
-
-
Hafezparast, M.1
Klocke, R.2
Ruhrberg, C.3
Marquardt, A.4
Ahmad-Annuar, A.5
Bowen, S.6
Lalli, G.7
Witherden, A.S.8
Hummerich, H.9
Nicholson, S.10
-
12
-
-
0028847436
-
Changes in expression of NR-1 and c-jun mRNA in rat lumbar spinal cord after neonatal common peroneal nerve crush
-
Hay C, Virgo L, Mentis G, Navarrete R, de Belleroche J (1995) Changes in expression of NR-1 and c-jun mRNA in rat lumbar spinal cord after neonatal common peroneal nerve crush. Brain Res 704:145-150
-
(1995)
Brain Res
, vol.704
, pp. 145-150
-
-
Hay, C.1
Virgo, L.2
Mentis, G.3
Navarrete, R.4
De Belleroche, J.5
-
13
-
-
33646683358
-
Swelling and vacuolisation of mitochondria in transgenic SOD1-ALS mice: A consequence of supranormal SOD1 expression?
-
author reply 50-41
-
Jaarsma D (2006) Swelling and vacuolisation of mitochondria in transgenic SOD1-ALS mice: a consequence of supranormal SOD1 expression? Mitochondrion 6:48-49, author reply 50-141
-
(2006)
Mitochondrion
, vol.6
, pp. 48-49
-
-
Jaarsma, D.1
-
14
-
-
0034520591
-
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1
-
Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC (2000) Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1. Neurobiol Dis 7:623-643
-
(2000)
Neurobiol Dis
, vol.7
, pp. 623-643
-
-
Jaarsma, D.1
Haasdijk, E.D.2
Grashorn, J.A.3
Hawkins, R.4
Van Duijn, W.5
Verspaget, H.W.6
London, J.7
Holstege, J.C.8
-
15
-
-
31544467869
-
Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models
-
Jonsson PA, Graffmo KS, Andersen PM, Brannstrom T, Lindberg M, Oliveberg M, Marklund SL (2006) Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models. Brain 129:451-464
-
(2006)
Brain
, vol.129
, pp. 451-464
-
-
Jonsson, P.A.1
Graffmo, K.S.2
Andersen, P.M.3
Brannstrom, T.4
Lindberg, M.5
Oliveberg, M.6
Marklund, S.L.7
-
16
-
-
0037273847
-
Progressive dystonia in a 12-year-old boy
-
Klepper J, Schaper J, Raca G, Coryell J, Das S, Hayflick SJ, Voit T (2003) Progressive dystonia in a 12-year-old boy. Eur J Paediatr Neurol 7:85-88
-
(2003)
Eur J Paediatr Neurol
, vol.7
, pp. 85-88
-
-
Klepper, J.1
Schaper, J.2
Raca, G.3
Coryell, J.4
Das, S.5
Hayflick, S.J.6
Voit, T.7
-
17
-
-
2442546517
-
Prenatal alteration and distribution of the GABA(B1) and GABA(B2) receptor subunit mRNAs during rat central nervous system development
-
Li S, Park MS, Kim MO (2004) Prenatal alteration and distribution of the GABA(B1) and GABA(B2) receptor subunit mRNAs during rat central nervous system development. Brain Res Dev Brain Res 150:141-150
-
(2004)
Brain Res Dev Brain Res
, vol.150
, pp. 141-150
-
-
Li, S.1
Park, M.S.2
Kim, M.O.3
-
18
-
-
42549129406
-
BMP inhibition enhances axonal growth and functional recovery after spinal cord injury
-
Matsuura I, Taniguchi J, Hata K, Saeki N, Yamashita T (2008) BMP inhibition enhances axonal growth and functional recovery after spinal cord injury. J Neurochem 105:1471-1479
-
(2008)
J Neurochem
, vol.105
, pp. 1471-1479
-
-
Matsuura, I.1
Taniguchi, J.2
Hata, K.3
Saeki, N.4
Yamashita, T.5
-
19
-
-
76749135687
-
Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration
-
Meyer M, Gonzalez Deniselle MC, Garay LI, Monachelli GG, Lima A, Roig P, Guennoun R, Schumacher M, De Nicola AF (2010) Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration. Cell Mol Neurobiol 30(1):123-135
-
(2010)
Cell Mol Neurobiol
, vol.30
, Issue.1
, pp. 123-135
-
-
Meyer, M.1
Gonzalez Deniselle, M.C.2
Garay, L.I.3
Monachelli, G.G.4
Lima, A.5
Roig, P.6
Guennoun, R.7
Schumacher, M.8
De Nicola, A.F.9
-
20
-
-
49549111127
-
Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking
-
Nonis D, Schmidt MH, van de Loo S, Eich F, Dikic I, Nowock J, Auburger G (2008) Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking. Cell Signal 20:1725-1739
-
(2008)
Cell Signal
, vol.20
, pp. 1725-1739
-
-
Nonis, D.1
Schmidt, M.H.2
Van De Loo, S.3
Eich, F.4
Dikic, I.5
Nowock, J.6
Auburger, G.7
-
21
-
-
69249220446
-
Spinal cord mRNA profile in patients with ALS: Comparison with transgenic mice expressing the human SOD-1 mutant
-
Offen D, Barhum Y, Melamed E, Embacher N, Schindler C, Ransmayr G (2009) Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant. J Mol Neurosci 38:85-93
-
(2009)
J Mol Neurosci
, vol.38
, pp. 85-93
-
-
Offen, D.1
Barhum, Y.2
Melamed, E.3
Embacher, N.4
Schindler, C.5
Ransmayr, G.6
-
22
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
-
Pasinelli P, Brown RH (2006) Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat Rev 7:710-723
-
(2006)
Nat Rev
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
23
-
-
34447633192
-
Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis
-
Pehar M, Vargas MR, Robinson KM, Cassina P, Diaz-Amarilla PJ, Hagen TM, Radi R, Barbeito L, Beckman JS (2007) Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. J Neurosci 27: 7777-7785
-
(2007)
J Neurosci
, vol.27
, pp. 7777-7785
-
-
Pehar, M.1
Vargas, M.R.2
Robinson, K.M.3
Cassina, P.4
Diaz-Amarilla, P.J.5
Hagen, T.M.6
Radi, R.7
Barbeito, L.8
Beckman, J.S.9
-
24
-
-
2442624720
-
Monomeric Cu, Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis
-
Rakhit R, Crow JP, Lepock JR, Kondejewski LH, Cashman NR, Chakrabartty A (2004) Monomeric Cu, Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis. J Biol Chem 279:15499-15504
-
(2004)
J Biol Chem
, vol.279
, pp. 15499-15504
-
-
Rakhit, R.1
Crow, J.P.2
Lepock, J.R.3
Kondejewski, L.H.4
Cashman, N.R.5
Chakrabartty, A.6
-
25
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH Jr et al (1996) Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet 13:43-47
-
(1996)
Nat Genet
, vol.13
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
Kowall, N.W.4
Ferrante, R.J.5
Siwek, D.F.6
Wilcox, H.M.7
Flood, D.G.8
Beal, M.F.9
Brown Jr., R.H.10
-
26
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
Rothstein JD (2009) Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 65(Suppl 1): S3-S9
-
(2009)
Ann Neurol
, vol.65
, Issue.SUPPL. 1
-
-
Rothstein, J.D.1
-
27
-
-
0034326790
-
Six important themes in amyotrophic lateral sclerosis (ALS) research
-
Rothstein JD (2009) Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 65(Suppl 1): S3-S9 Rowland LP (2000) Six important themes in amyotrophic lateral sclerosis (ALS) research, 1999. J Neurol Sci 180:2-6
-
(1999)
J Neurol Sci
, vol.180
, pp. 2-6
-
-
Rowland, L.P.1
-
28
-
-
65149101697
-
Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS
-
Shan X, Vocadlo D, Krieger C (2009) Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS. Neurosci Lett 458:70-74
-
(2009)
Neurosci Lett
, vol.458
, pp. 70-74
-
-
Shan, X.1
Vocadlo, D.2
Krieger, C.3
-
29
-
-
70849113863
-
Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization
-
Teilum K, Smith MH, Schulz E, Christensen LC, Solomentsev G, Oliveberg M, Akke M (2009) Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization. Proc Natl Acad Sci USA 106:18273-18278
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18273-18278
-
-
Teilum, K.1
Smith, M.H.2
Schulz, E.3
Christensen, L.C.4
Solomentsev, G.5
Oliveberg, M.6
Akke, M.7
-
30
-
-
0038460810
-
Adult Hallervorden-Spatz syndrome simulating amyotrophic lateral sclerosis
-
Vasconcelos OM, Harter DH, Duffy C, McDonough B, Seidman JG, Seidman CE, Campbell WW (2003) Adult Hallervorden-Spatz syndrome simulating amyotrophic lateral sclerosis. Muscle Nerve 28:118-122
-
(2003)
Muscle Nerve
, vol.28
, pp. 118-122
-
-
Vasconcelos, O.M.1
Harter, D.H.2
Duffy, C.3
McDonough, B.4
Seidman, J.G.5
Seidman, C.E.6
Campbell, W.W.7
-
31
-
-
0028903269
-
Induction of the immediate early gene c-jun in human spinal cord in amyotrophic lateral sclerosis with concomitant loss of NMDA receptor NR-1 and glycine transporter mRNA
-
Virgo L, de Belleroche J (1995) Induction of the immediate early gene c-jun in human spinal cord in amyotrophic lateral sclerosis with concomitant loss of NMDA receptor NR-1 and glycine transporter mRNA. Brain Res 676:196-204
-
(1995)
Brain Res
, vol.676
, pp. 196-204
-
-
Virgo, L.1
De Belleroche, J.2
-
32
-
-
64549124726
-
Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse
-
Wang L, Deng HX, Grisotti G, Zhai H, Siddique T, Roos RP (2009) Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse. Hum Mol Genet 18:1642-1651
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1642-1651
-
-
Wang, L.1
Deng, H.X.2
Grisotti, G.3
Zhai, H.4
Siddique, T.5
Roos, R.P.6
-
34
-
-
0037460835
-
Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis
-
Wilczak N, de Vos RA, De Keyser J (2003) Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis. Lancet 361:1007-1011
-
(2003)
Lancet
, vol.361
, pp. 1007-1011
-
-
Wilczak, N.1
De Vos, R.A.2
De Keyser, J.3
-
35
-
-
34447550238
-
Interaction between familial amyotrophic lateral sclerosis (ALS)- Linked SOD1 mutants and the dynein complex
-
Zhang F, Strom AL, Fukada K, Lee S, Hayward LJ, Zhu H (2007) Interaction between familial amyotrophic lateral sclerosis (ALS)- linked SOD1 mutants and the dynein complex. J Biol Chem 282:16691-16699
-
(2007)
J Biol Chem
, vol.282
, pp. 16691-16699
-
-
Zhang, F.1
Strom, A.L.2
Fukada, K.3
Lee, S.4
Hayward, L.J.5
Zhu, H.6
|