Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli

Nature Biotechnology

Volumn 28, Issue 7, 2010, Pages 727-732

  Chatterjee, Manash S ^a   Purvis, Jeremy E ^b   Brass, Lawrence F ^b   Diamond, Scott L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD SUBSTITUTES; CALCIUM; CYTOLOGY; FORECASTING; LOCOMOTIVES; PLATELETS; RAILROAD CARS; SIGNALING;

CALCIUM SIGNALING; CELL BIOLOGY; CELLULAR RESPONSE; CELLULAR SIGNALING; COMBINATORIAL COMPLEXITY; COMPLEX SIGNAL; DOSE RESPONSE; INPUT SIGNAL; NEURAL NETWORK MODEL; PAIR-WISE COMBINATIONS; PHENOTYPIC RESPONSE; SIGNALING PATHWAYS;

NEURAL NETWORKS;

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; CONVULXIN; PEPTIDE DERIVATIVE; PROSTAGLANDIN E2; ALANYL-TYROSYL-PROLYL-GLYCYL-LYSYL-PHENYLALANINE; LECTIN; OLIGOPEPTIDE; PEPTIDE FRAGMENT; SNAKE VENOM; THROMBIN RECEPTOR PEPTIDE (42-47);

ARTICLE; ARTIFICIAL NEURAL NETWORK; CALCIUM SIGNALING; CONTROLLED STUDY; HUMAN; HUMAN CELL; PHENOTYPE; PLASMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; DOSE RESPONSE; DRUG EFFECTS; METABOLISM;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADENOSINE DIPHOSPHATE; BLOOD PLATELETS; CROTALID VENOMS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LECTINS, C-TYPE; NEURAL NETWORKS (COMPUTER); OLIGOPEPTIDES; PEPTIDE FRAGMENTS; SIGNAL TRANSDUCTION;

EID: 77954522738     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1642     Document Type: Article

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