Cloning and sequencing of complete BoNT gene of Clostridium botulinum type A for therapy

Chinese Journal of Biologicals

Volumn 23, Issue 6, 2010, Pages 598-601

  Zhao, Ya Jing ^a   Wei, Ran ^a   Liu, Chen Ming ^a  

^a LANZHOU INSTITUTE OF BIOLOGICAL PRODUCTS   (China)

Author keywords

Cloning; Clostridium botulinum type A; Neurotoxins; Sequencing

Indexed keywords

BOTULINUM TOXIN A; NUCLEOTIDE;

ARTICLE; AT RICH SEQUENCE; BACTERIAL STRAIN; CHINA; CLOSTRIDIUM BOTULINUM TYPE A; GC RICH SEQUENCE; GENBANK; GENE AMPLIFICATION; GENE SEQUENCE; GENE VECTOR; GENETIC TRAIT; MOLECULAR CLONING; NONHUMAN; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; QUALITY CONTROL; RECOMBINANT PLASMID; SEQUENCE HOMOLOGY;

CLOSTRIDIUM BOTULINUM;

EID: 77954521540     PISSN: 10045503     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Jacobson MJ, Lin G, Whittam TS, et al. Phylogenetic analysis of Clostridium botulinum type A by multi-locus sequence typing [J]. Microbiology, 2008, 154 (Pt8): 2408-2415.
2. Zhou Y, Paturi S, Lindo P, et al. Cloning, expression, purification and characterization of biologically active recombinant hemagglutinin-33, type A botulinum neurotoxin associated protein [J]. Protein, 2007, 26 (1): 29-37.
3. Panicker JN, Muthane UB. Botulinum toxins: pharmacology and its current therapeutic evidence for use [J]. Neurol India, 2003, 51 (4): 455-460.
4. Schulte-Mattler WJ, Leinisch E. Role of botulinum toxin in migraine therapy [J]. Drug Develop Res, 2008, 68 (7): 397-402.
5. Salles AG, Toledo PN, Ferreira MC. Botulinum toxin injection in long-standing facial paralysis patients: improvement of facial symmetry observed up to 6 months [J]. Aesthetic Plast Surg, 2009, 33 (4): 582-590.
6. Kitamura M. Identification of RNA species in the RNA-toxin complex and structure of the complex in Clostridium botulinum tyoe E. Biochem Biophys Res Commun, 2002, 291 (1): 154-157. (Pubitemid 34681152)
7. Schiavo G, Rossetto O, Santucci A, et al. Botulinum neurotoxins are zinc proteins [J]. J Biol Chem, 1992, 267 (33): 23479-23483. (Pubitemid 23088143)