Comparative study of cellular and synaptic abnormalities in brain tissue samples from pediatric tuberous sclerosis complex and cortical dysplasia type II

Epilepsia

Volumn 51, Issue SUPPL. 3, 2010, Pages 160-165

  Cepeda, Carlos ^a   André, Véronique M ^a   Yamazaki, Irene ^a   Hauptman, Jason S ^a   Chen, Jane Y ^a   Vinters, Harry V ^a   Mathern, Gary W ^a   Levine, Michael S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain malformations; Dysplastic cells; Electrophysiology; Epilepsy; Slice; Taylor cortical dysplasia

Indexed keywords

BRAIN ELECTROPHYSIOLOGY; BRAIN TISSUE; CELL DISRUPTION; CELL STRUCTURE; CELL TYPE; CELLULAR DISTRIBUTION; CLINICAL FEATURE; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; CORTICAL DYSPLASIA; DISEASE CLASSIFICATION; DISEASE SEVERITY; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIAL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; TUBEROUS SCLEROSIS;

BRAIN; CHILD, PRESCHOOL; HUMANS; MALFORMATIONS OF CORTICAL DEVELOPMENT; MEMBRANE POTENTIALS; PYRAMIDAL CELLS; SEIZURES; SYNAPTIC POTENTIALS; TUBEROUS SCLEROSIS;

EID: 77954512649     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02633.x     Document Type: Conference Paper

References (21)

1. Andre VM, Wu N, Yamazaki I, Nguyen ST, Fisher RS, Vinters HV, Mathern GW, Levine MS, Cepeda C. (2007) Cytomegalic interneurons: a new abnormal cell type in severe pediatric cortical dysplasia. J Neuropathol Exp Neurol 66:491-504.
2. Cepeda C, Hurst RS, Flores-Hernandez J, Hernandez-Echeagaray E, Klapstein GJ, Boylan MK, Calvert CR, Jocoy EL, Nguyen OK, Andre VM, Vinters HV, Ariano MA, Levine MS, Mathern GW. (2003) Morphological and electrophysiological characterization of abnormal cell types in pediatric cortical dysplasia. J Neurosci Res 72:472-486.
3. Cepeda C, Andre VM, Flores-Hernandez J, Nguyen OK, Wu N, Klapstein GJ, Nguyen S, Koh S, Vinters HV, Levine MS, Mathern GW. (2005) Pediatric cortical dysplasia: correlations between neuroimaging, electrophysiology and location of cytomegalic neurons and balloon cells and glutamate/GABA synaptic circuits. Dev Neurosci 27:59-76.
4. Cepeda C, Andre VM, Levine MS, Salamon N, Miyata H, Vinters HV, Mathern GW. (2006) Epileptogenesis in pediatric cortical dysplasia: the dysmature cerebral developmental hypothesis. Epilepsy Behav 9:219-235.
5. Chandra PS, Salamon N, Nguyen ST, Chang JW, Huynh MN, Cepeda C, Leite JP, Neder L, Koh S, Vinters HV, Mathern GW. (2007) Infantile spasm-associated microencephaly in tuberous sclerosis complex and cortical dysplasia. Neurology 68:438-445.
6. Curatolo P, Bombardieri R, Jozwiak S. (2008) Tuberous sclerosis. Lancet 372:657-668.
7. Horikawa K, Armstrong WE. (1988) A versatile means of intracellular labeling: injection of biocytin and its detection with avidin conjugates. J Neurosci Methods 25:1-11.
8. Jansen FE, Braams O, Vincken KL, Algra A, Anbeek P, Jennekens- Schinkel A, Halley D, Zonnenberg BA, van den Ouweland A, van Huffelen AC, van Nieuwenhuizen O, Nellist M (2008) Overlapping neurologic and cognitive phenotypes in patients with TSC1 or TSC2 mutations. Neurology 70:908-915.
9. Lamparello P, Baybis M, Pollard J, Hol EM, Eisenstat DD, Aronica E, Crino PB. (2007) Developmental lineage of cell types in cortical dysplasia with balloon cells. Brain 130:2267-2276.
10. Lerner JT, Salamon N, Hauptman JS, Velasco TR, Hemb M, Wu JY, Sankar R, Donald Shields W, Engel J Jr, Fried I, Cepeda C, Andre VM, Levine MS, Miyata H, Yong WH, Vinters HV, Mathern GW. (2009) Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience. Epilepsia 50:1310-1335.
11. Leung AK, Robson WL. (2007) Tuberous sclerosis complex: a review. J Pediatr Health Care 21:108-114.
12. Mathern GW, Giza CC, Yudovin S, Vinters HV, Peacock WJ, Shewmon DA, Shields WD. (1999) Postoperative seizure control and antiepileptic drug use in pediatric epilepsy surgery patients: the UCLA experience, 1986-1997. Epilepsia 40:1740-1749.
13. Mathern GW, Cepeda C, Hurst RS, Flores-Hernandez J, Mendoza D, Levine MS. (2000) Neurons recorded from pediatric epilepsy surgery patients with cortical dysplasia. Epilepsia 41(Suppl 6):S162-S167.
14. Mathern GW, Andres M, Salamon N, Chandra PS, Andre VM, Cepeda C, Levine MS, Leite JP, Neder L, Vinters HV. (2007) A hypothesis regarding the pathogenesis and epileptogenesis of pediatric cortical dysplasia and hemimegalencephaly based on MRI cerebral volumes and NeuN cortical cell densities. Epilepsia 48(Suppl 5):74-78.
15. Palmini A, Najm I, Avanzini G, Babb T, Guerrini R, Foldvary-Schaefer N, Jackson G, Luders HO, Prayson R, Spreafico R, Vinters HV. (2004) Terminology and classification of the cortical dysplasias. Neurology 62:S2-S8.
16. Sparagana SP, Roach ES. (2000) Tuberous sclerosis complex. Curr Opin Neurol 13:115-119.
17. Taylor DC, Falconer MA, Bruton CJ, Corsellis JA. (1971) Focal dysplasia of the cerebral cortex in epilepsy. J Neurol Neurosurg Psychiatry 34:369-387.
18. Vinters HV, De Rosa MJ, Farrell MA. (1993) Neuropathologic study of resected cerebral tissue from patients with infantile spasms. Epilepsia 34:772-779. (Pubitemid 23228146)
19. Wang Y, Greenwood JS, Calcagnotto ME, Kirsch HE, Barbaro NM, Baraban SC. (2007) Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1. Ann Neurol 61:139-152.
20. Wu JY, Salamon N, Kirsch HE, Mantle MM, Nagarajan SS, Kurelowech L, Aung MH, Sankar R, Shields WD, Mathern GW. (2009) Non-invasive testing and early surgery linked with seizure freedom in tuberous sclerosis complex. Neurology 74,392-398.
21. Zecevic N. (2004) Specific characteristic of radial glia in the human fetal telencephalon. Glia 48:27-35.