Mechanisms of synchronous activity in cerebellar Purkinje cells

Journal of Physiology

Volumn 588, Issue 13, 2010, Pages 2373-2390

  Wise, Andrew K ^a   Cerminara, Nadia L ^a   Marple Horvat, Dilwyn E ^a,b   Apps, Richard ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE; XYLAZINE;

ARTICLE; BRAIN CELL; BRAIN DEPTH STIMULATION; BRAIN REGION; CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; ADULT; ANIMAL EXPERIMENT; BRAIN CORTEX; CEREBELLUM; CEREBRAL CRUS; CONTROLLED STUDY; CRUS II; ELECTROSTIMULATION; MICROELECTRODE; PARAMEDIAN LOBULE; PARAVERMAL C1 ZONE; POSTERIOR LOBE OF CEREBELLUM; SPIKE WAVE; VERMAL A2 ZONE; ANIMAL; CYTOLOGY; DRUG EFFECTS; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; PERIPHERAL NERVE; PHYSIOLOGY; SPRAGUE DAWLEY RAT; WISTAR RAT;

ANIMALS; CEREBELLUM; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIALS; PERIPHERAL NERVES; PURKINJE CELLS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

EID: 77954503030     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.189704     Document Type: Article

References (70)

1. Aizenman CD, Linden DJ. Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum. J Neurophysiol 1999, 82:1697-1709.
2. Apps R, Garwicz M. Anatomical and physiological foundations of cerebellar information processing. Nat Rev Neurosci 2005, 6:297-311.
3. Apps R, Hawkes R. Cerebellar cortical organization: a one-map hypothesis. Nat Rev Neurosci 2009, 10:670-681.
4. Armstrong DM. Supraspinal contributions to the initiation and control of locomotion in the cat. Prog Neurobiol 1986, 26:273-361.
5. Armstrong DM, Harvey RJ, Schild RF. Cerebello-cerebellar responses mediated via climbing fibres. Exp Brain Res 1973a, 18:19-39.
6. Armstrong DM, Harvey RJ, Schild RF. The spatial organisation of climbing fibre branching in the cat cerebellum. Exp Brain Res 1973b, 18:40-58.
7. Armstrong DM, Harvey RJ, Schild RF. Spino-olivocerebellar pathways to the posterior lobe of the cat cerebellum. Exp Brain Res 1973c, 18:1-18.
8. Armstrong DM, Rawson JA. Activity patterns of cerebellar cortical neurones and climbing fibre afferents in the awake cat. J Physiol 1979, 289:425-448.
9. Atkins MJ, Apps R. Somatotopical organisation within the climbing fibre projection to the paramedian lobule and copula pyramidis of the rat cerebellum. J Comp Neurol 1997, 389:249-263.
10. Bell CC, Grimm RJ. Discharge properties of Purkinje cells recorded on single and double microelectrodes. J Neurophysiol 1969, 32:1044-1055.
11. Bell CC, Kawasaki T. Relations among climbing fiber responses of nearby Purkinje cells. J Neurophysiol 1972, 35:155-169.
12. Bengtsson F, Jorntell H. Ketamine and xylazine depress sensory-evoked parallel fiber and climbing fiber responses. J Neurophysiol 2007, 98:1697-1705.
13. Cerminara NL, Apps R, Marple-Horvat DE. An internal model of a moving visual target in the lateral cerebellum. J Physiol 2009, 587:429-442.
14. Cerminara NL, Rawson JA. Evidence that climbing fibers control an intrinsic spike generator in cerebellar Purkinje cells. J Neurosci 2004, 24:4510-4517.
15. Devor A, Yarom Y. Generation and propagation of subthreshold waves in a network of inferior olivary neurons. J Neurophysiol 2002, 87(6):3059-69.
16. De Zeeuw CI, Koekkoek SK, Wylie DR, Simpson JI. Association between dendritic lamellar bodies and complex spike synchrony in the olivocerebellar system. J Neurophysiol 1997, 77:1747-1758.
17. De Zeeuw CI, Lang EJ, Sugihara I, Ruigrok TJ, Eisenman LM, Mugnaini E, Llinás R. Morphological correlates of bilateral synchrony in the rat cerebellar cortex. J Neurosci 1996, 16:3412-3426.
18. De Zeeuw CI, Wylie DR, DiGiorgi PL, Simpson JI. Projections of individual Purkinje cells of identified zones in the flocculus to the vestibular and cerebellar nuclei in the rabbit. J Comp Neurol 1994, 349:428-447.
19. Drummond GB. Reporting ethical matters in The Journal of Physiology: standards and advice. J Physiol 2009, 587:713-719.
20. Eccles JC, Llinás R, Sasaki K. The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum. J Physiol 1966, 182:268-296.
21. Gauck V, Jaeger D. The control of rate and timing of spikes in the deep cerebellar nuclei by inhibition. J Neurosci 2000, 20:3006-3016.
22. Gauck V, Jaeger D. The contribution of NMDA and AMPA conductances to the control of spiking in neurons of the deep cerebellar nuclei. J Neurosci 2003, 23:8109-8118.
23. Gerstein GL, Perkel DH. Mutual temporal relationships among neuronal spike trains. Statistical techniques for display and analysis. Biophys J 1972, 12:453-473.
24. Hamori J, Szentagothai J. Identification of synapses formed in the cerebellar cortex by Purkinje axon collaterals: an electron microscope study. Exp Brain Res 1968, 5:118-128.
25. Häusser M, Clark BA. Tonic synaptic inhibition modulates neuronal output pattern and spatiotemporal synaptic integration. Neuron 1997, 19:665-678.
26. Heck DH, Thach WT, Keating JG. On-beam synchrony in the cerebellum as the mechanism for the timing and coordination of movement. Proc Nat Acad Sci U S A 2007, 104:7658-7663.
27. Hounsgaard J, Midtgaard J. Intrinsic determinants of firing pattern in Purkinje cells of the turtle cerebellum in vitro. J Physiol 1988, 402:731-749.
28. Lang EJ. Organization of olivocerebellar activity in the absence of excitatory glutamatergic input. J Neurosci 2001, 21:1663-1675.
29. Lang EJ. GABAergic and glutamatergic modulation of spontaneous and motor-cortex-evoked complex spike activity. J Neurophysiol 2002, 87:1993-2008.
30. Lang EJ. Excitatory afferent modulation of complex spike synchrony. Cerebellum 2003, 2:165-170.
31. Lang EJ, Sugihara I, Llinás R. GABAergic modulation of complex spike activity by the cerebellar nucleoolivary pathway in rat. J Neurophysiol 1996, 76:255-275.
32. Lang EJ, Sugihara I, Welsh JP, Llinás R. Patterns of spontaneous Purkinje cell complex spike activity in the awake rat. J Neurosci 1999, 19:2728-2739.
33. Lemkey-Johnston N, Larramendi LM. Types and distribution of synapses upon basket and stellate cells of the mouse cerebellum: an electron microscopic study. J Comp Neurol 1968, 134:73-112.
34. Llinás R, Baker R, Sotelo C. Electrotonic coupling between neurons in cat inferior olive. J Neurophysiol 1974, 37:560-571.
35. Llinás R, Sasaki K. the functional organization of the olivo-cerebellar system as examined by multiple Purkinje cell recordings. Eur J Neurosci 1989, 1:587-602.
36. Llinás R, Sugimori M. Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices. J Physiol 1980, 305:171-195.
37. Llinás R, Yarom Y. Electrophysiology of mammalian inferior olivary neurones in vitro. Different types of voltage-dependent ionic conductances. J Physiol 1981a, 315:549-567.
38. Llinás R, Yarom Y. Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro. J Physiol 1981b, 315:569-584.
39. Loewenstein Y, Mahon S, Chadderton P, Kitamura K, Sompolinsky H, Yarom Y, Häusser M. Bistability of cerebellar Purkinje cells modulated by sensory stimulation. Nat Neurosci 2005, 8:202-211.
40. Lou JS, Bloedel JR. Responses of sagittally aligned Purkinje cells during perturbed locomotion: synchronous activation of climbing fiber inputs. J Neurophysiol 1992, 68:570-580.
41. McCrea RA, Bishop GA, Kitai ST. Intracellular staining of Purkinje cells and their axons with horseradish peroxidase. Brain Res 1976, 118:132-136.
42. McKay BE, Turner RW. Physiological and morphological development of the rat cerebellar Purkinje cell. J Physiol 2005, 567:829-850.
43. Marshall SP, Lang EJ. Local changes in the excitability of the cerebellar cortex produce spatially restricted changes in complex spike synchrony. J Neurosci 2009, 29:14352-14362.
44. Marshall SP, Van Der Giessen RS, De Zeeuw CI, Lang EJ. Altered olivocerebellar activity patterns in the connexin36 knockout mouse. Cerebellum 2007, 6:287-299.
45. Ozden I, Sullivan MR, Lee HM, Wang SS. Reliable coding emerges from coactivation of climbing fibers in microbands of cerebellar Purkinje neurons. J Neurosci 2009, 29:10463-10473.
46. Palkovits M, Mezey E, Hamori J, Szentagothai J. Quantitative histological analysis of the cerebellar nuclei in the cat. I. Numerical data on cells and on synapses. Exp Brain Res 1977, 28:189-209.
47. Pardoe J, Apps R. Structure-function relations of two somatotopically corresponding regions of the rat cerebellar cortex: olivo-cortico-nuclear connections. Cerebellum 2002, 1:165-184.
48. Pijpers A, Apps R, Pardoe J, Voogd J, Ruigrok TJ. Precise spatial relationships between mossy fibers and climbing fibers in rat cerebellar cortical zones. J Neurosci 2006, 26:12067-12080.
49. Ros H, Sachdev RN, Yu Y, Sestan N, McCormick DA. Neocortical networks entrain neuronal circuits in cerebellar cortex. J Neurosci 2009, 29:10309-10320.
50. Ruigrok TJ, Cella F. Precerebellar nuclei and red nucleus. The Rat Nervous System 1995, 277-308. Paxinos G, In, ed, pp, Academic Press, Sydney
51. Sasaki K, Bower JM, Llinás R. Multiple Purkinje cell recording in rodent cerebellar cortex. Eur J Neurosci 1989, 1:572-586.
52. Schulman JA, Bloom FE. Golgi cells of the cerebellum are inhibited by inferior olive activity. Brain Res 1981, 210:350-355.
53. Schultz SR, Kitamura K, Post-Uiterweer A, Krupic J, Häusser M. Spatial pattern coding of sensory information by climbing fiber-evoked calcium signals in networks of neighboring cerebellar Purkinje cells. J Neurosci 2009, 29:8005-8015.
54. Schwarz C, Welsh JP. Dynamic modulation of mossy fiber system throughput by inferior olive synchrony: a multielectrode study of cerebellar cortex activated by motor cortex. J Neurophysiol 2001, 86:2489-2504.
55. Shin SL, De Schutter E. Dynamic synchronization of Purkinje cell simple spikes. J Neurophysiol 2006, 96:3485-3491.
56. Sotelo C, Llinás R, Baker R. Structural study of inferior olivary nucleus of the cat: morphological correlates of electrotonic coupling. J Neurophysiol 1974, 37:541-559.
57. Steuber V, Mittmann W, Hoebeek FE, Silver RA, De Zeeuw CI, Häusser M, De Schutter E. Cerebellar LTD and pattern recognition by Purkinje cells. Neuron 2007, 54:121-136.
58. Sugihara I. Organization and remodeling of the olivocerebellar climbing fiber projection. Cerebellum 2006, 5:15-22.
59. Sugihara I, Lang EJ, Llinás R. Uniform olivocerebellar conduction time underlies Purkinje cell complex spike synchronicity in the rat cerebellum. J Physiol 1993, 470:243-271.
60. Sugihara I, Lang EJ, Llinás R. Serotonin modulation of inferior olivary oscillations and synchronicity: a multiple-electrode study in the rat cerebellum. Eur J Neurosci 1995, 7:521-534.
61. Sugihara I, Wu HS, Shinoda Y. The entire trajectories of single olivocerebellar axons in the cerebellar cortex and their contribution to cerebellar compartmentalization. J Neurosci 2001, 21:7715-7723.
62. Thach WT. Discharge of Purkinje and cerebellar nuclear neurons during rapidly alternating arm movements in the monkey. J Neurophysiol 1968, 31:785-797.
63. Thach WT. Somatosensory receptive fields of single units in cat cerebellar cortex. J Neurophysiol 1967, 30:675-696.
64. Voogd J, Glickstein M. The anatomy of the cerebellum. Trends Neurosci 1998, 21:370-375.
65. Voogd J, Pardoe J, Ruigrok TJ, Apps R. The distribution of climbing and mossy fiber collateral branches from the copula pyramidis and the paramedian lobule: congruence of climbing fiber cortical zones and the pattern of zebrin banding within the rat cerebellum. J Neurosci 2003, 23:4645-4656.
66. Welsh JP, Lang EJ, Sugihara I, Llinás R. Dynamic organization of motor control within the olivocerebellar system. Nature 1995, 374:453-457.
67. Welsh JP, Llinás R. Some organizing principles for the control of movement based on olivocerebellar physiology. Prog Brain Res 1997, 114:449-461.
68. Woodward DJ, Hoffer BJ, Altman J. Physiological and pharmacological properties of Purkinje cells in rat cerebellum degranulated by postnatal x-irradiation. J Neurobiol 1974, 5:283-304.
69. Wylie DR, De Zeeuw CI, Simpson JI. Temporal relations of the complex spike activity of Purkinje cell pairs in the vestibulocerebellum of rabbits. J Neurosci 1995, 15:2875-2887.
70. Xu W, Edgley SA. Climbing fibre-dependent changes in Golgi cell responses to peripheral stimulation. J Physiol 2008, 586:4951-4959.