Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs

Virology Journal

Volumn 7, Issue , 2010, Pages

  Suphaphiphat, Pirada ^a,b,c   Franti, Michael ^a,b,c   Hekele, Armin ^a,b,c   Lilja, Anders ^a,b,c   Spencer, Terika ^a,b,c   Settembre, Ethan ^a,b,c   Palmer, Gene ^a,b,c   Crotta, Stefania ^d   Tuccino, Annunziata B ^a,b,c   Keiner, Bjoern ^a,b,c   Trusheim, Heidi ^a,b,c   Balabanis, Kara ^a,b,c   Sackal, Melissa ^a,b,c   Rothfeder, Mithra ^a,b,c   Mandl, Christian W ^a,b,c   Dormitzer, Philip R ^a,b,c   Mason, Peter W ^a,b,c  

^a NOVARTIS VACCINES AND DIAGNOSTICS   (United States)

^b NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^c GSK Marburg Vaccines and Diagnostics   (Germany)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; VIRUS HEMAGGLUTININ; HEMAGGLUTININ H1, H1N1 INFLUENZA VIRUS; INFLUENZA VIRUS HEMAGGLUTININ;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EGG; GENE MUTATION; INFLUENZA; INFLUENZA VIRUS A H1N1; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PANDEMIC; SWINE INFLUENZA VIRUS; VACCINE PRODUCTION; VIROGENESIS; VIRUS CULTURE; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; CHICK EMBRYO; DOG; EPIDEMIC; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; POINT MUTATION; SEQUENCE ALIGNMENT; VIROLOGY;

ORTHOMYXOVIRIDAE; SUIDAE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHICK EMBRYO; DISEASE OUTBREAKS; DOGS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MOLECULAR SEQUENCE DATA; POINT MUTATION; SEQUENCE ALIGNMENT; VIRUS REPLICATION;

EID: 77954485464     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-7-157     Document Type: Article

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