Polymerase chain reaction detection of HPV in squamous carcinoma of the oropharynx

American Journal of Clinical Pathology

Volumn 134, Issue 1, 2010, Pages 36-41

  Agoston, Elin S ^a   Robinson, Stephen J ^b   Mehra, Karishma K ^a   Birch, Chandler ^a   Semmel, Dana ^a   Mirkovic, Jelena ^c   Haddad, Robert I ^a   Posner, Marshall R ^a   Kindelberger, David ^a   Krane, Jeffrey F ^a   Brodsky, Joshua ^a   Crum, Christopher P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BOSTON UNIVERSITY   (United States)

^c TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16;

ARTICLE; CONTROLLED STUDY; ECONOMIC EVALUATION; HISTOPATHOLOGY; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERMETHOD COMPARISON; NONHUMAN; OROPHARYNX CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SQUAMOUS CELL CARCINOMA; VIRUS DETECTION; WART VIRUS;

CARCINOMA, SQUAMOUS CELL; DNA, NEOPLASM; DNA, VIRAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; NEOPLASM PROTEINS; OROPHARYNGEAL NEOPLASMS; OROPHARYNX; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; TUMOR MARKERS, BIOLOGICAL;

EID: 77954473796     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCP1AAWXE5JJCLZ     Document Type: Article

References (46)

1. Syrjanen S. HPV infections and tonsillar carcinoma. J Clin Pathol. 2004;57:449-455.
2. Haddad R, Crum C, Chen Z, et al. HPV16 transmission between a couple with HPV-related head and neck cancer. Oral Oncol. 2008;44:812-815. (Pubitemid 351992917)
3. Lee WT, Tubbs RR, Teker AM, et al. Use of in situ hybridization to detect human papillomavirus in head and neck squamous cell carcinoma patients without a history of alcohol or tobacco use. Arch Pathol Lab Med. 2008;132:1653-1656.
4. Nasman A, Attner P, Hammarstedt L, et al. Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma? Int J Cancer. 2009;125:362-366.
5. Romanitan M, Nasman A, Ramqvist T, et al. Human papillomavirus frequency in oral and oropharyngeal cancer in Greece. Anticancer Res. 2008;28:2077-2080.
6. Badaracco G, Rizzo C, Mafera B, et al. Molecular analyses and prognostic relevance of HPV in head and neck tumours. Oncol Rep. 2007;17:931-939.
7. Paz IB, Cook N, Odom-Maryon T, et al. Human papillomavirus (HPV) in head and neck cancer: an association of HPV 16 with squamous cell carcinoma of Waldeyer's tonsillar ring. Cancer. 1997;79:595-604.
8. El-Mofty SK, Lu DW. Prevalence of human papillomavirus type 16 DNA in squamous cell carcinoma of the palatine tonsil, and not the oral cavity, in young patients: a distinct clinicopathologic and molecular disease entity. Am J Surg Pathol. 2003;27:1463-1470.
9. Gillison ML, Koch WM, Shah KV. Human papillomavirus in head and neck squamous cell carcinoma: are some head and neck cancers a sexually transmitted disease? Curr Opin Oncol. 1999;11:191-199.
10. D'Souza G, Kreimer AR, Viscidi R, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007;356:1944-1956.
11. Ryerson AB, Peters ES, Coughlin SS, et al. Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998-2003. Cancer. 2008;113:2901-2909.
12. Smith EM, Wang D, Kim Y, et al. P16INK4a expression, human papillomavirus, and survival in head and neck cancer. Oral Oncol. 2008;44:133-142. (Pubitemid 351179656)
13. Chung YL, Lee MY, Horng CF, et al. Use of combined molecular biomarkers for prediction of clinical outcomes in locally advanced tonsillar cancers treated with chemoradiotherapy alone. Head Neck. 2009;31:9-20.
14. Klozar J, Kratochvil V, Salakova M, et al. HPV status and regional metastasis in the prognosis of oral and oropharyngeal cancer. Eur Arch Otorhinolaryngol. 2008;265(suppl 1):S75-S82.
15. Kuo K-T, Hsiao C-H, Lin C-H, et al. The biomarkers of human papillomavirus infection in tonsillar squamous cell carcinoma: molecular basis and predicting favorable outcome. Mod Pathol. 2008;21:376-386.
16. Cohen MA, Basha SR, Reichenbach DK, et al. Increased viral load correlates with improved survival in HPV-16-associated tonsil carcinoma patients. Acta Otolaryngol. 2008;128:583-589.
17. Dahlstrand H, Nasman A, Romanitan M, et al. Human papillomavirus accounts both for increased incidence and better prognosis in tonsillar cancer. Anticancer Res. 2008;28:1133-1138. (Pubitemid 351578850)
18. Charfi L, Jouffroy T, de Cremoux P, et al. Two types of squamous cell carcinoma of the palatine tonsil characterized by distinct etiology, molecular features and outcome. Cancer Lett. 2008;260:72-78.
19. Sedaghat AR, Zhang Z, Begum S, et al. Prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinomas. Laryngoscope. 2009;119:1542-1549.
20. Lassen P, Eriksen JG, Hamilton-Dutoit S, et al. Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. J Clin Oncol. 2009;27:1992-1998.
21. Rischin D, Young R, Fisher R, et al. Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial [abstract]. J Clin Oncol. 2009;27(suppl):15s. Abstract.
22. Gillison M, Harris J, Westra W, et al. Survival outcomes by tumor human papillomavirus (HPV) status in stage III-IV oropharyngeal cancer (OPC) in RTOG 0129 [abstract]. J Clin Oncol. 2009;27(suppl):15s. Abstract 6003.
23. Begum S, Cao D, Gillison M, et al. Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma. Clin Cancer Res. 2005;11:5694-5699.
24. Goldenberg D, Begum S, Westra WH, et al. Cystic lymph node metastasis in patients with head and neck cancer: an HPV-associated phenomenon. Head Neck. 2008;30:898-903.
25. Pai RK, Erickson J, Pourmand N, et al. p16(INK4A) immunohistochemical staining may be helpful in distinguishing branchial cleft cysts from cystic squamous cell carcinomas originating in the oropharynx. Cancer. 2009;117:108-119.
26. Stenson K. Epidemiology and risk factors for head and neck squamous cell cancer. In: Basow DS, ed. UpToDate. Waltham, MA: UpToDate; 2009. Available at UpToDate.com.
27. Tate JE, Yang YC, Shen J, et al. A comparison of early (E7) and late (L1) primer-mediated amplification of papillomaviral DNA in cervical neoplasia. Mol Cell Probes. 1996;10:347-351.
28. Manos MM, Wright DK, Lewis AJ, et al. The use of polymerase chain reaction amplification for the detection of genital human papillomaviruses. In: Furth M, Greaves M, eds. Molecular Diagnostics of Human Cancer. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1989:209-214.
29. Genden EM, Ferlito A, Scully C, et al. Current management of tonsillar cancer. Oral Oncol. 2003;39:337-342.
30. Begum S, Gillison ML, Ansari-Lari MA, et al. Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin. Clin Cancer Res. 2003;9:6469-6475. (Pubitemid 38031835)
31. Shibata DK, Arnheim N, Martin WJ. Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction. J Exp Med. 1988;167:225-230. (Pubitemid 18093706)
32. Resnick RM, Cornelissen MT, Wright DK, et al. Detection and typing of human papillomavirus in archival cervical cancer specimens by DNA amplification with consensus primers. J Natl Cancer Inst. 1990;82:1477-1484.
33. Lungu O, Wright TC Jr, Silverstein S. Typing of human papillomaviruses by polymerase chain reaction amplification with L1 consensus primers and RFLP analysis. Mol Cell Probes. 1992;6:145-152.
34. Diagnostic and therapeutic technology assessment. Human papillomavirus DNA testing in the management of cervical neoplasia. JAMA. 1993;270:2975-2981.
35. Zitz JC, McLachlin CM, Tate JE, et al. Restriction fragment length polymorphism analysis of isotype-labeled polymerase chain reaction-amplified human papillomavirus DNA combines sensitivity with built-in contaminant detection. Mod Pathol. 1994;7:407-411.
36. Howley PM. Role of the human papillomaviruses in human cancer. Cancer Res. 1991;51(18 suppl):5019s-5022s.
37. Yang YC, Shen J, Tate JE, et al. Cervical cancer in young women in Taiwan: prognosis is independent of papillomavirus or tumor cell type. Gynecol Oncol. 1997;64:59-63.
38. Jeon S, Lambert PF. Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis. Proc Natl Acad Sci U S A. 1995;92:1654-1658.
39. Cullen AP, Reid R, Campion M, et al. Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm. J Virol. 1991;65:606-612.
40. Ernster JA, Sciotto CG, O'Brien MM, et al. Prevalence of oncogenic human papillomavirus 16 and 18 in the palatine tonsils of the general adult population. Arch Otolaryngol Head Neck Surg. 2009;135:554-557.
41. Andl T, Kahn T, Pfuhl A, et al. Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control. Cancer Res. 1998;58:5-13.
42. Chen R, Aaltonen LM, Vaheri A. Human papillomavirus type 16 in head and neck carcinogenesis. Rev Med Virol. 2005;15:351-363. (Pubitemid 41598001)
43. Ottinger M, Christalla T, Nathan K, et al. Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4-and BRD2/RING3-induced G1 cell cycle arrest. J Virol. 2006;80:10772-10786.
44. An FQ, Compitello N, Horwitz E, et al. The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest. J Biol Chem. 2005;280:3862-3874.
45. Moens U, Johannessen M. Human polyomaviruses and cancer: expanding repertoire. J Dtsch Dermatol Ges. 2008;6:704-708.
46. Reimers N, Kasper HU, Weissenborn SJ, et al. Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. Int J Cancer. 2007;120:1731-1738.