Systemic antibiotic treatment of clinical endometritis in dairy cows with ceftiofur or two doses of cloprostenol in a 14-d interval

Animal Reproduction Science

Volumn 121, Issue 1-2, 2010, Pages 55-62

  Kaufmann, T B ^a   Westermann, S ^a   Drillich, M ^a   Plontzke J ^a   Heuwieser, W ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Antibiotic treatment; Endometritis; Prostaglandin; Reproductive performance

Indexed keywords

ANTIINFECTIVE AGENT; CEFTIOFUR; CEPHALOSPORIN DERIVATIVE; CLOPROSTENOL; LUTEOLYTIC AGENT;

ANIMAL; ANIMAL DISEASE; ARTICLE; ARTIFICIAL INSEMINATION; CATTLE; CATTLE DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAIRYING; DRUG ADMINISTRATION; DRUG EFFECT; ENDOMETRITIS; FEMALE; INTRAMUSCULAR DRUG ADMINISTRATION; PHYSIOLOGY; PREGNANCY; PREGNANCY RATE; RANDOMIZED CONTROLLED TRIAL; REPRODUCTION; BOVINAE; CATTLE DISEASES; DRUG EFFECTS; VETERINARY;

ANIMALS; ANTI-BACTERIAL AGENTS; CATTLE; CATTLE DISEASES; CEPHALOSPORINS; CLOPROSTENOL; DAIRYING; DRUG ADMINISTRATION SCHEDULE; ENDOMETRITIS; FEMALE; INJECTIONS, INTRAMUSCULAR; INSEMINATION, ARTIFICIAL; LUTEOLYTIC AGENTS; PREGNANCY; PREGNANCY RATE; REPRODUCTION;

BOS;

EID: 77954460169     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2010.04.190     Document Type: Article

References (45)

1. Barlund C.S., Carruthers T.D., Waldner C.L., Palmer C.W. A comparison of diagnostic techniques for postpartum endometritis in dairy cattle. Theriogenology 2008, 69:714-723.
2. Braun M., Zerbe H., Kietzmann M. Tissue concentration of intrauterine and intravenously administered amoxicillin in the isolated hemoperfused bovine uterus model and in healthy cows. Berliner und Munchener tierarztliche Wochenschrift 2009, 122:51-57.
3. Bretzlaff K.N., Ott R.S., Koritz G.D., Bevill R.F.B., Gustafsson K., Davis L.E. Distribution of oxytetracycline in genital tract tissues of postpartum cows given the drug by intravenous and intrauterine routes. Am. J. Vet. Res. 1983, 44:764-769.
4. Cartmill J.A., El-Zarkouny S.Z., Hensley B.A., Lamb G.C., Stevenson J.S. Stage of cycle, incidence, and timing of ovulation, and pregnancy rates in dairy cattle after three timed breeding protocols. J. Dairy Sci. 2001, 84:1051-1059.
5. Chenault J.R., McAllister J.F., Chester S.T., Dame K.J., Kausche F.M., Robb E.J. Efficacy of ceftiofur hydrochloride sterile suspension administered parenterally for the treatment of acute postpartum metritis in dairy cows. J. Am. Vet. Med. Assoc. 2004, 224:1634-1639.
6. Dohmen M.J.W., Lohuis J.A.C.M., Huszenicza G., Nagy P., Gacs M. The relationship between bacteriological and clinical findings in cows with subacute/chronic endometritis. Theriogenology 1995, 43:1379-1388.
7. Drillich M., Arlt S., Kersting S., Bergwerff A.A., Scherpenisse P., Heuwieser W. Ceftiofur derivatives in serum, uterine tissues, cotyledons, and lochia after fetal membrane retention. J. Dairy Sci. 2006, 89:3431-3438.
8. Drillich M., Beetz O., Pfutzner A., Sabin M., Sabin H.J., Kutzer P., Nattermann H., Heuwieser W. Evaluation of a systemic antibiotic treatment of toxic puerperal metritis in dairy cows. J. Dairy Sci. 2001, 84:2010-2017.
9. Drillich M., Raab D., Wittke M., Heuwieser W. Treatment of chronic endometritis in dairy cows with an intrauterine application of enzymes. A field trial. Theriogenology 2005, 63:1811-1823.
10. Drillich M., Wittke M., Tenhagen B.A., Unsicker C., Heuwieser W. Behandlung chronischer Endometritiden bei Milchkühen mit Cephapirin, Tiaprost oder einer Kombination aus beiden Wirkstoffen. Tierärztl Prax 2005, 33:404-410.
11. Falkenberg U., Heuwieser W. Einfluss des Startzzeitpunktes eines Prostaglandin F2alpha Programms bei der Behandlung der chronischen Endometritis beim Milchrind auf die Fruchtbarkeitsleistung. 1. Berliner Tagung " Fruchtbarkeit beim weiblichen Rind" 2005, Tierklinik für Fortpflanzung, FU Berlin, p. 72.
12. Földi J., Kulcsar M., Pecsi A., Huyghe B., de Sa C., Lohuis J.A., Cox P., Huszenicza G. Bacterial complications of postpartum uterine involution in cattle. Anim. Reprod. Sci. 2006, 96:265-281.
13. Gabler C., Drillich M., Fischer C., Holder C., Heuwieser W., Einspanier R. Endometrial expression of selected transcripts involved in prostaglandin synthesis in cows with endometritis. Theriogenology 2009, 71:993-1004.
14. Herath S., Lilly S.T., Fischer D.P., Williams E.J., Dobson H., Bryant C.E., Sheldon I.M. Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F2alpha to prostaglandin E2 in bovine endometrium. Endocrinology 2009, 150:1912-1920.
15. Heuwieser W., Tenhagen B.A., Tischer M., Luhr J., Blum H. Effect of three programmes for the treatment of endometritis on the reproductive performance of a dairy herd. Vet. Rec. 2000, 146:338-341.
16. Janowski T., Zdunczyk S., Mwaanga E.S. Combined gnRH and PGF2alpha application in cows with endometritis puerperalis treated with antibiotics. Reprod. Domest. Anim. 2001, 36:244-246.
17. Kasimanickam R., Duffield T.F., Foster R.A., Gartley C.J., Leslie K.E., Walton J.S., Johnson W.H. Endometrial cytology and ultrasonography for the detection of subclinical endometritis in postpartum dairy cows. Theriogenology 2004, 62:9-23.
18. Kaufmann T.B., Drillich M., Tenhagen B.A., Forderung D., Heuwieser W. Prevalence of bovine subclinical endometritis 4h after insemination and its effects on first service conception rate. Theriogenology 2009, 71:385-391.
19. Knutti B., Kupfer U., Busato A. Reproductive efficiency of cows with endometritis after treatment with intrauterine infusions or prostaglandin injections, or no treatment. J. Vet. Med. Ser. A 2000, 47:609-615.
20. LeBlanc M.M., Causey R.C. Clinical and subclinical endometritis in the mare: both threats to fertility. Reprod. Domest. Anim. 2009, 44(Suppl. 3):10-22.
21. LeBlanc S.J., Duffield T.F., Leslie K.E., Bateman K.G., Keefe G.P., Walton J.S., Johnson W.H. Defining and diagnosing postpartum clinical endometritis and its impact on reproductive performance in dairy cows. J. Dairy Sci. 2002, 85:2223-2236.
22. LeBlanc S.J., Duffield T.F., Leslie K.E., Bateman K.G., Keefe G.P., Walton J.S., Johnson W.H. The effect of treatment of clinical endometritis on reproductive performance in dairy cows. J. Dairy Sci. 2002, 85:2237-2249.
23. Leung S.T., Cheng Z., Sheldrick E.L., Derecka K., Derecka K., Flint A.P., Wathes D.C. The effects of lipopolysaccharide and interleukins-1alpha,-2 and -6 on oxytocin receptor expression and prostaglandin production in bovine endometrium. J. Endocrinol. 2001, 168:497-508.
24. Lincke A., Drillich M., Heuwieser W. Subclinical endometritis in dairy cattle and its effect on reproductive performance-a review on recent publications. Berliner und Munchener tierarztliche Wochenschrift 2006, 120:245-250.
25. Masera J., Gustafsson B.K., Afiefy M.M., Stowe C.M., Bergt G.P. Disposition of oxytetracycline in the bovine genital tract: systemic vs intrauterine administration. J. Am. Vet. Med. Assoc. 1980, 176:1099-1102.
26. McDougall S., Macaulay R., Compton C. Association between endometritis diagnosis using a novel intravaginal device and reproductive performance in dairy cattle. Anim. Reprod. Sci. 2007, 99:9-23.
27. Okker H., Schmitt E.J., Vos P.L.A.M., Scherpenisse P., Bergwerff A.A., Jonker F.H. Pharmacokinetics of ceftiofur in plasma and uterine secretions and tissues after subcutaneous postpartum administration in lactating dairy cows. J. Vet. Pharmacol. Ther. 2002, 25:33-38.
28. Paisley L.G., McKelsen W.D., Anderson P.B. Mechanisms and therapy for retained fetal membranes and uterine infections of cows: a review. Theriogenology 1986, 25:353-381.
29. Pepper R.T., Dobson H. Preliminary results of treatment and endocrinology of chronic endometritis in the dairy cow. Vet. Rec. 1987, 120:53-56.
30. Petit T., Spergser J., Rosengarten R., Aurich J. Prevalence of potentially pathogenic bacteria as genital pathogens in dairy cattle. Reprod. Domest. Anim. 2009, 44:88-91.
31. Pleticha S., Drillich M., Heuwieser W. Evaluation of the Metricheck device and the gloved hand for the diagnosis of clinical endometritis in dairy cows. J. Dairy Sci. 2009, 92:5429-5435.
32. Pursley J.R., Kosorok M.R., Wiltbank M.C. Reproductive management of lactating dairy cows using synchronization of ovulation. J. Dairy Sci. 1997, 80:301-306.
33. Runciman D.J., Anderson G.A., Malmo J. Comparison of two methods of detecting purulent vaginal discharge in postpartum dairy cows and effect of intrauterine cephapirin on reproductive performance. Aust. Vet. J. 2009, 87:369-378.
34. Runciman D.J., Anderson G.A., Malmo J., Davis G.M. Use of postpartum vaginoscopic (visual vaginal) examination of dairy cows for the diagnosis of endometritis and the association of endometritis with reduced reproductive performance. Aust. Vet. J. 2008, 86:205-213.
35. Sheldon I.M., Bushnell M., Montgomery J., Rycroft A.N. Minimum inhibitory concentrations of some antimicrobial drugs against bacteria causing uterine infections in cattle. Vet. Rec. 2004, 155:383-387.
36. Sheldon I.M., Lewis G.S., LeBlanc S., Gilbert R.O. Defining postpartum uterine disease in cattle. Theriogenology 2006, 65:1516-1530.
37. Sheldon I.M., Noakes D.E. Comparison of three treatments for bovine endometritis. Vet. Rec. 1998, 142:575-579.
38. Sheldon I.M., Noakes D.E., Rycroft A.N., Dobson H. Effect of postpartum manual examination of the vagina on uterine bacterial contamination in cows. Vet. Rec. 2002, 151:531-534.
39. Sheldon I.M., Price S.B., Cronin J., Gilbert R.O., Gadsby J.E. Mechanisms of infertility associated with clinical and subclinical endometritis in high producing dairy cattle. Reprod. Domest. Anim. 2009, 44(Suppl. 3):1-9.
40. Sheldon I.M., Wathes D.C., Dobson H. The management of bovine reproduction in elite herds. Vet. J. 2006, 171:70-78.
41. Stewart P.S., Costerton J.W. Antibiotic resistance of bacteria in biofilms. Lancet 2001, 358:135-138.
42. Tenhagen B.A., Surholt R., Wittke M., Vogel C., Drillich M., Heuwieser W. Use of Ovsynch in dairy herds-differences between primiparous and multiparous cows. Anim. Reprod. Sci. 2004, 81:1-11.
43. Weems C.W., Weems Y.S., Randel R.D. Prostaglandins and reproduction in female farm animals. Vet. J. 2006, 171:206-228.
44. Williams E.J., Fischer D.P., Pfeiffer D.U., England G.C., Noakes D.E., Dobson H., Sheldon I.M. Clinical evaluation of postpartum vaginal mucus reflects uterine bacterial infection and the immune response in cattle. Theriogenology 2005, 63:102-117.
45. Zhou C., Boucher J.F., Dame K.J., Moreira M., Graham R., Nantel J., Zuidhof S., Arfi L., Flores R., Neubauer G., Olson J. Multilocation trial of ceftiofur for treatment of postpartum cows with fever. J. Am. Vet. Med. Assoc. 2001, 219:805-808.