Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type β-lactamase genes in gram-negative isolates

Journal of Clinical Microbiology

Volumn 48, Issue 7, 2010, Pages 2618-2622

  Endimiani, Andrea ^a,b   Hujer, Andrea M ^a,b   Hujer, Kristine M ^a,b   Gatta, Julian A ^a   Schriver, Andrew C ^a   Jacobs, Michael R ^b   Rice, Louis B ^a   Bonomo, Robert A ^a,b  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE CTX M; BETA LACTAMASE KPC; BETA LACTAMASE SHV; BETA LACTAMASE TEM 1; UNCLASSIFIED DRUG; BACTERIAL DNA; BACTERIAL PROTEIN;

ACINETOBACTER BAUMANNII; ARTICLE; BACTERIUM ISOLATE; DNA MICROARRAY; ENTEROBACTERIACEAE; GENE IDENTIFICATION; GRAM NEGATIVE BACTERIUM; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; CHEMISTRY; COMPARATIVE STUDY; DNA SEQUENCE; EVALUATION STUDY; GENETICS; GRAM NEGATIVE INFECTION; HUMAN; MICROBIOLOGY; POLYMERASE CHAIN REACTION; PROCEDURES;

NEGIBACTERIA;

BACTERIAL PROTEINS; BETA-LACTAMASES; DNA, BACTERIAL; EVALUATION STUDIES AS TOPIC; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA;

EID: 77954445751     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00568-10     Document Type: Article

References (23)

1. Bush, K., and G. A. Jacoby. 2010. An updated functional classification of β-lactamases. Antimicrob. Agents Chemother. 54:969-976.
2. Cornaglia, G., and G. M. Rossolini. 2010. The emerging threat of acquired carbapenemases in Gram-negative bacteria. Clin. Microbiol. Infect. 16:99-101.
3. KPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system. J. Antimicrob. Chemother. 64:1102-1110.
4. KPC-containing Klebsiella pneumoniae isolates detected in different institutions in the eastern USA. J. Antimicrob. Chemother. 63:427-437.
5. Endimiani, A., F. Luzzaro, R. Migliavacca, E. Mantengoli, A. M. Hujer, K. M. Hujer, L. Pagani, R. A. Bonomo, G. M. Rossolini, and A. Toniolo. 2007. Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum β-lactamase. Antimicrob. Agents Chemother. 51:2211-2214.
6. Endimiani, A., and D. L. Paterson. 2007. Optimizing therapy for infections caused by enterobacteriaceae producing extended-spectrum β-lactamases. Semin. Respir. Crit. Care Med. 28:646-655.
7. Gniadkowski, M. 2008. Evolution of extended-spectrum β-lactamases by mutation. Clin. Microbiol. Infect. 14(Suppl.)1:11-32.
8. Grimm, V., S. Ezaki, M. Susa, C. Knabbe, R. D. Schmid, and T. T. Bachmann. 2004. Use of DNA microarrays for rapid genotyping of TEM β-lactamases that confer resistance. J. Clin. Microbiol. 42:3766-3774.
9. Kitchel, B., J. K. Rasheed, J. B. Patel, A. Srinivasan, S. Navon-Venezia, Y. Carmeli, A. Brolund, and C. G. Giske. 2009. Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258. Antimicrob. Agents Chemother. 53:3365-3370.
10. Leinberger, D. M., V. Grimm, M. Rubtsova, J. Weile, K. Schroppel, T. A. Wichelhaus, C. Knabbe, R. D. Schmid, and T. T. Bachmann. 2010. Integrated detection of extended-spectrum-β-lactam resistance by DNA microarray-based genotyping of TEM, SHV, and CTX-M genes. J. Clin. Microbiol. 48:460-471.
11. Luzzaro, F., G. Gesu, A. Endimiani, G. Ortisi, S. Malandrin, L. Pagani, and G. M. Rossolini. 2006. Performance in detection and reporting β-lactam resistance phenotypes in Enterobacteriaceae: a nationwide proficiency study in Italian laboratories. Diagn. Microbiol. Infect. Dis. 55:311-318.
12. Miriagou, V., G. Cornaglia, M. Edelstein, I. Galani, C. G. Giske, M. Gniadkowski, E. Malamou-Lada, L. Martinez-Martinez, F. Navarro, P. Nordmann, L. Peixe, S. Pournaras, G. M. Rossolini, A. Tsakris, A. Vatopoulos, and R. Canton. 2010. Acquired carbapenemases in Gram-negative bacterial pathogens: detection and surveillance issues. Clin. Microbiol. Infect. 16:112-122.
13. Nordmann, P., G. Cuzon, and T. Naas. 2009. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect. Dis. 9:228-236.
14. Paterson, D. L., and R. A. Bonomo. 2005. Extended-spectrum β-lactamases: a clinical update. Clin. Microbiol. Rev. 18:657-686.
15. Paterson, D. L., K. M. Hujer, A. M. Hujer, B. Yeiser, M. D. Bonomo, L. B. Rice, and R. A. Bonomo. 2003. Extended-spectrum β-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-type β-lactamases. Antimicrob. Agents Chemother. 47:3554-3560.
16. Pitout, J. D., A. Hossain, and N. D. Hanson. 2004. Phenotypic and molecular detection of CTX-M-β-lactamases produced by Escherichia coli and Klebsiella spp. J. Clin. Microbiol. 42:5715-5721. (Pubitemid 39664358)
17. Pitout, J. D., and K. B. Laupland. 2008. Extended-spectrum β-lactamaseproducing Enterobacteriaceae: an emerging public-health concern. Lancet Infect. Dis. 8:159-166.
18. Poirel, L., C. Heritier, I. Podglajen, W. Sougakoff, L. Gutmann, and P. Nordmann. 2003. Emergence in Klebsiella pneumoniae of a chromosomeencoded SHV β-lactamase that compromises the efficacy of imipenem. Antimicrob. Agents Chemother. 47:755-758.
19. Queenan, A. M., and K. Bush. 2007. Carbapenemases: the versatile β-lactamases. Clin. Microbiol. Rev. 20:440-458.
20. Rasheed, J. K., G. J. Anderson, H. Yigit, A. M. Queenan, A. Domenech- Sanchez, J. M. Swenson, J. W. Biddle, M. J. Ferraro, G. A. Jacoby, and F. C. Tenover. 2000. Characterization of the extended-spectrum β-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18. Antimicrob. Agents Chemother. 44:2382-2388.
21. Tenover, F. C., M. J. Mohammed, T. S. Gorton, and Z. F. Dembek. 1999. Detection and reporting of organisms producing extended-spectrum β-lactamases: survey of laboratories in Connecticut. J. Clin. Microbiol. 37:4065-4070.
22. Wolter, D. J., P. M. Kurpiel, N. Woodford, M. F. Palepou, R. V. Goering, and N. D. Hanson. 2009. Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4. Antimicrob. Agents Chemother. 53:557-562.
23. Zhu, L. X., Z. W. Zhang, D. Liang, D. Jiang, C. Wang, N. Du, Q. Zhang, K. Mitchelson, and J. Cheng. 2007. Multiplex asymmetric PCR-based oligonucleotide microarray for detection of drug resistance genes containing single mutations in Enterobacteriaceae. Antimicrob. Agents Chemother. 51:3707-3713.