Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: Results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database

Journal of Rheumatology

Volumn 37, Issue 7, 2010, Pages 1488-1501

  Avouac, Jerome ^cx   Walker, Ulrich ^ez   Tyndall, Alan ^ez   Kahan, André ^cx   Matucci Cerinic, Marco ^a   Allanore, Yannick ^cx   Miniati, I ^a   Muller A ^b   Iannone, F ^c   Giacomelli, R ^d   Distler, O ^e   Becvar, R ^f   Sierakowsky, S ^g   Kowal Bielecka, O ^g   Coelho, P ^h   Cabane, J ⁱ   Cutolo, M ^j   Shoenfeld, Y ^k   Valentini, G ^l   Rovensky, J ^m   Riemekasten, G ⁿ   Nicoara, I ^o   Vlachoyiannopoulos, P ^p   Caporali, R ^q   Jiri, S ^f   Inanc, M ^r   Gorska, I Zimmermann ^s   Carreira, P ^t   Novak, S ^u   Czirjak, L ^v   Ramos, F Oliveira ^w   Jendro, M ^x   Chizzolini, C ^y   Kucharz, E J ^z   Richter, J ^aa   Cozzi, F ^ab   Rozman, B ^ac   Mallia, C M ^ad   Gabrielli, A ^ae   Farge, D ^af   Kiener, H P ^ag   Schoffel D ^ah   Sticherling, M ^ai   Airo, P ^aj   Wollheim, F ^ak   Martinovic, D ^al   Trotta, F ^am   Hunzelmann, N ^an   Jablonska, S ^ad   Reich, K ^ao   Bombardieri, S ^ap   Siakka, P ^aq   Pellerito, R ^ar   Bambara, L M ^as   Morovic Vergles, J ^at   Denton, C ^au   Hinrichs, R ^av   Van Den Hoogen, F ^aw   Damjanov, N ^ax   Kotter I ^ay   Ortiz, V ^az   Heitmann, S ^ba   Krasowska, D ^bb   Seidel, M ^bc   Hasler, P ^bd   Van Laar, J M ^be   Kaltwasser, J P ^bf   Foeldvari, I ^bg   Juan Mas, A ^bh   Bajocchi, G ^bi   Wislowska, M ^bj   Pereira Da Silva, J A ^bk   Jacobsen, S ^bl   Worm, M ⁿ   Graniger, W ^bm   Kuhn, A ^aa   Stankovic, A ^bn   Cossutta, R ^bo   Majdan, M ^bb   Rajcevska, L Damjanovska ^bp   Tikly, M ^bq   Nasonov, E L ^br   Steinbrink, K ^bs   Herrick, A ^bt   Muller Ladner U ^bu   Dinc, A ^bv   Scorza, R ^bw   Sondergaard, K ^bx   Indiveri, F ^by   Nielsen, H ^ad   Szekanecz, Z ^bz   Silver, R M ^ca   Antivalle, M ^cb   Espinosa, I B ^cc   Garcia De La Pena Lefebvre P ^cd   Midtvedt, O ^ce   Launay, D ^cf   Valesini, F ^cg   Tuvik, P ^ch   Ionescu, R M ^ci   Del Papa, N ^cj   Pinto, S ^ck   Wigley, F ^cl   Mihai, C ^cm   Capranu, M Sinziana ^cn   Sunderkotter C ^co   Jun, J B ^cp   Derk, C ^cq   Alhasani, S ^cr   Distler, J H ^ad   Ton, E ^cs   Soukup, T ^ct   Seibold, J ^cu   Zeni, S ^cv   Nash, P ^cw   Mouthon, L ^cx   De Keyser, F ^cy   Duruoz M T ^cz   Cantatore, F P ^da   Strauss, G ^db   Von Mulhen C A ^dc   Pozzi, M R ^dd   Eyerich, K ^de   Szechinski, J ^df   Keiserman, M ^dg   Houssiau, F A ^dh   Rom Ivorra, J A ^di   Krummel Lorenz, B ^dj   Aringer, M ^dk   Westhovens, R ^dl   Bellisai, F ^dm   Mayer, M ^dn   Stoeckl, F ^do   Uprus M ^dp   Volpe, A ^dq   Buslau, M ^dr   Yavuz, S ^ds   Granel, B ^dt   Feijó, A Valderílio ^du   Del Galdo, F ^cq   Popa, S ^dv   Zenone, T ^dw   Machado, X Ricardo ^dx   Pileckyte, M ^dy   Stebbings, S ^dz   Mathieu, A ^ea   Tulli, A ^eb   Tourinho, T ^ec   Souza, R ^ed   Acayaba De Toledo, R ^ee   Stamp, L ^ef   Solanki, K ^eg   Veale, D ^eh   Neto, J Francisco Marques ^ei   Bagnato, G F ^ej   Loyo, E ^ek   Toloza, S ^el   Li, M ^em   Mohamed, W Ahmed Abdel Atty ^en   Cobankara, V ^eo   Olas, J ^ep   Salsano, F ^cg   Oksel, F ^eq   Tanaseanu, C M ^er   Foti, R ^es   Ancuta, C ^et   Vonk, M ^aw   Caramashi, P ^as   Beretta, L ^cv   Balbir, A ^ad   Shine, B ^ad   Chiala A ^c   Simic, K Pasalic ^ax   Ghio, M ^eu   Stamenkovic, B ^ev   Rednic, S ^o   Host, N ^ew   Hachulla, E ^ex   Furst, D E ^ey   more..

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c UNIVERSITY OF BARI   (Italy)

^d UNIVERSITY OF L'AQUILA   (Italy)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^f CHARLES UNIVERSITY   (Czech Republic)

^g MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^h INSTITUTO PORTUGUÊS DE REUMATOLOGIA   (Portugal)

ⁱ HÔPITAL SAINT ANTOINE   (France)

^j UNIVERSITY OF GENOA   (Italy)

^k TEL AVIV UNIVERSITY   (Israel)

^l FEDERICO II UNIVERSITY HOSPITAL   (Italy)

^m NATIONAL INSTITUTE OF RHEUMATIC DISEASES   (Slovakia)

ⁿ CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^o IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^p UNIVERSITY OF ATHENS   (Greece)

^q FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^r ISTANBUL UNIVERSITY   (Turkey)

^s POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^t HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^u KBC RIJEKA   (Croatia)

^v UNIVERSITY OF PÉCS   (Hungary)

^w HOSPITAL DE SANTA MARIA   (Portugal)

^x SAARLAND UNIVERSITY   (Germany)

^y UNIVERSITY HOSPITAL   (Switzerland)

^z MEDICAL UNIVERSITY OF SILESIA   (Poland)

^aa HEINRICH HEINE UNIVERSITY   (Germany)

^ab UNIVERSITY OF PADOVA   (Italy)

^ac UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^ad Stella Maris ^*  (Israel)

^ae UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^af SAINT LOUIS HOSPITAL   (France)

^ag UNIVERSITY OF VIENNA   (Austria)

^ah Westpfalz Klinikum GmbH   (Germany)

^ai UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^aj Servizio di Reumatologia e Immunologia Clinica   (Italy)

^ak LUND UNIVERSITY HOSPITAL   (Sweden)

^al UNIVERSITY HOSPITAL SPLIT   (Croatia)

^am UNIVERSITY OF FERRARA   (Italy)

^an UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^ao UNIVERSITY OF GÖTTINGEN   (Germany)

^ap UNIVERSITY OF PISA   (Italy)

^aq Agios Pavlos General Hospital   (Greece)

^ar MAURIZIANO HOSPITAL   (Italy)

^as UNIVERSITY OF VERONA   (Italy)

^at University of Zagreb School of Medicine   (Croatia)

^au ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^av UNIVERSITY OF ULM   (Germany)

^aw RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^ax INSTITUTE OF RHEUMATOLOGY   (Serbia)

^ay UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^az Rheumatology Granollers General Hospital   (Spain)

^ba MARIENHOSPITAL STUTTGART   (Germany)

^bb MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^bc UNIVERSITY HOSPITAL BONN   (Germany)

^bd CANTONAL HOSPITAL AARAU   (Switzerland)

^be LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^bf UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^bg Kinder und Jugendrheumatologie   (Germany)

^bh HOSPITAL SON LLÀTZER   (Spain)

^bi S MARIA NUOVA HOSPITAL   (Italy)

^bj MSW and A Hospital   (Poland)

^bk CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^bl UNIVERSITY OF COPENHAGEN   (Denmark)

^bm MEDICAL UNIVERSITY OF GRAZ   (Austria)

^bn Institute for Prevention Treatment and Rehabilitation Rheumatic and Cardiovascular Disease   (Serbia)

^bo HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^bp SS CYRIL AND METHODIUS UNIVERSITY   (Macedonia)

^bq UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^br V A NASONOVA RESEARCH INSTITUTE OF RHEUMATOLOGY   (Russian Federation)

^bs JOHANNES GUTENBERG UNIVERSITY   (Germany)

^bt UNIVERSITY OF MANCHESTER   (United Kingdom)

^bu KERCKHOFF HEART CENTER   (Germany)

^bv GULHANE SCHOOL OF MEDICINE   (Turkey)

^bw UO Immunologia Clinica   (Italy)

^bx AARHUS UNIVERSITY HOSPITAL   (Denmark)

^by UNIVERSITY OF GENOA   (Italy)

^bz UNIVERSITY OF DEBRECEN   (Hungary)

^ca Division of Rheumatology and Immunology   (United States)

^cb FATEBENEFRATELLI HOSPITAL   (Italy)

^cc HOSPITAL DE MENDARO   (Spain)

^cd HOSPITAL RAMÓN Y CAJAL   (Spain)

^ce OSLO UNIVERSITY HOSPITAL   (Norway)

^cf LILLE UNIVERSITY HOSPITAL   (France)

^cg SAPIENZA UNIVERSITY OF ROME   (Italy)

^ch North Estonian Regional Hospital   (Estonia)

^ci CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^cj Rheumatology   (Italy)

^ck HOSPITAL DE SÃO JOÃO   (Portugal)

^cl JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^cm CANTACUZINO INSTITUTE   (Romania)

^cn Department of Rheumatology   (Romania)

^co UNIVERSITY OF MÜNSTER   (Germany)

^cp Hanyang University Hospital for Rheumatic Diseases   (South Korea)

^cq THOMAS JEFFERSON UNIVERSITY   (United States)

^cr UNIVERSITY OF MOSUL   (Iraq)

^cs UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^ct UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

^cu UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^cv UNIVERSITY OF MILAN   (Italy)

^cw Rheumatology Research Unit   (Australia)

^cx Medical Faculty ^*  (France)

^cy GHENT UNIVERSITY   (Belgium)

^cz CELAL BAYAR UNIVERSITY   (Turkey)

^da UNIVERSITY OF FOGGIA   (Italy)

^db Mental Health Services CPH   (Denmark)

^dc Rheuma Clinic   (Brazil)

^dd Universita'degli Studi di Milano Bicocca   (Italy)

^de TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^df WROCLAW MEDICAL UNIVERSITY   (Poland)

^dg PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^dh CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^di HOSPITAL UNIVERSITARIO DR PESET   (Spain)

^dj Endokrinologikum   (Germany)

^dk UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^dl UNIVERSITY OF LEUVEN   (Belgium)

^dm UNIVERSITY OF SIENA   (Italy)

^dn KBC Zagreb   (Croatia)

^do KLINIKUM DARMSTADT   (Germany)

^dp East Tallinn Central Hospital   (Estonia)

^dq SACRO CUORE DON CALABRIA HOSPITAL   (Italy)

^dr Reha Rheinfelden   (Switzerland)

^ds MARMARA UNIVERSITY   (Turkey)

^dt HÔPITAL NORD   (France)

^du FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^dv Department of Rheumatology   (Moldova)

^dw Department of Medicine   (France)

^dx HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^dy KAUNAS UNIVERSITY OF MEDICINE HOSPITAL   (Lithuania)

^dz UNIVERSITY OF OTAGO   (New Zealand)

^ea UNIVERSITY OF CAGLIARI   (Italy)

^eb UNIVERSITY OF CHIETI   (Italy)

^ec Faculdade Federal de Ciências Médicas de Porto Alegre   (Brazil)

^ed UNIVERSITY OF SÃO PAULO   (Brazil)

^ee Faculdade de Medicina de São José Rio Preto   (Brazil)

^ef UNIVERSITY OF OTAGO   (New Zealand)

^eg UNIVERSITY OF WAIKATO   (New Zealand)

^eh ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^ei UNIVERSITY OF CAMPINAS   (Brazil)

^ej UNIVERSITY OF MESSINA   (Italy)

^ek Hospital Regional Universitario Jose Mar?a Cabral y Baez   (Dominican Republic)

^el Hospital San Juan Batista   (Argentina)

^em PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^en ALEXANDRIA UNIVERSITY   (Egypt)

^eo PAMUKKALE UNIVERSITY   (Turkey)

^ep Szpital Specjalistyczny Im J Dietla   (Poland)

^eq EGE UNIVERSITY   (Turkey)

^er St Pantelimon Clinical Emergency Hospital   (Romania)

^es Clinica Medica L Condorelli   (Italy)

^et Rheumatology Department   (Romania)

^eu UNIVERSITY OF GENOA   (Italy)

^ev University of Ni   (Serbia)

^ew BISPEBJERG HOSPITAL   (Denmark)

^ex Service de médecine nucléaire HÔpital Huriez   (France)

^ey UNIVERSITY OF CALIFORNIA   (United States)

^ez Felix Platter Spital   (Switzerland)

more..

Author keywords

Joint contracture; Joint involvement; Synovitis; Systemic sclerosis; Tendon friction rub

Indexed keywords

ADULT; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; DATA BASE; DISEASE ACTIVITY; DISEASE DURATION; ECHOGRAPHY; FEMALE; HAND RADIOGRAPHY; HUMAN; INFLAMMATION; INTERSTITIAL LUNG DISEASE; JOINT CONTRACTURE; JOINT RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RHEUMATIC DISEASE; SCLERODERMA; SKIN DISEASE; SYNOVITIS; SYSTEMIC SCLEROSIS; TENOSYNOVITIS;

ADULT; AGED; CLINICAL TRIALS AS TOPIC; CROSS-SECTIONAL STUDIES; DATABASES, FACTUAL; FEMALE; HUMANS; INFLAMMATION; JOINT DISEASES; JOINTS; MALE; MIDDLE AGED; RANGE OF MOTION, ARTICULAR; SCLERODERMA, LOCALIZED; SCLERODERMA, SYSTEMIC; SYNOVITIS; TENDONS;

EID: 77954436578     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.091165     Document Type: Article

References (37)

1. Allanore Y, Avouac J, Wipff J, Kahan A. New therapeutic strategies in the management of systemic sclerosis. Expert Opin Pharmacother 2007;8:607-15.
2. Richards HL, Herrick AL, Griffin K, Gwilliam PD, Loukes J, Fortune DG. Systemic sclerosis: patients' perceptions of their condition. Arthritis Rheum 2003;49:689-96. (Pubitemid 37296475)
3. Sandqvist G, Eklund M, Akesson A, Nordenskiold U. Daily activities and hand function in women with scleroderma. Scand J Rheumatol 2004;33:102-7.
4. Baron M, Lee P, Keystone EC. The articular manifestations of progressive systemic sclerosis (scleroderma). Ann Rheum Dis 1982;41:147-52. (Pubitemid 12158516)
5. Mau W, Listing J, Huscher D, Zeidler H, Zink A. Employment across chronic inflammatory rheumatic diseases and comparison with the general population. J Rheumatol 2005;32:721-8.
6. Brower LM, Poole JL. Reliability and validity of the Duruoz Hand Index in persons with systemic sclerosis (scleroderma). Arthritis Rheum 2004;51:805-9.
7. Poole JL, Gallegos M, O'Linc S. Reliability and validity of the Arthritis Hand Function Test in adults with systemic sclerosis (scleroderma). Arthritis Care Res 2000;13:69-73.
8. Poole JL, Steen VD. The use of the Health Assessment Questionnaire (HAQ) to determine physical disability in systemic sclerosis. Arthritis Care Res 1991;4:27-31.
9. Avouac J, Guerini H, Wipff J, Assous N, Chevrot A, Kahan A, et al. Radiological hand involvement in systemic sclerosis. Ann Rheum Dis 2006;65:1088-92.
10. La Montagna G, Sodano A, Capurro V, Malesci D, Valentini G. The arthropathy of systemic sclerosis: a 12 month prospective clinical and imaging study. Skeletal Radiol 2005;34:35-41. (Pubitemid 40089752)
11. Brun B, Serup J, Hagdrup H. Radiological changes of the hands in systemic sclerosis. Acta Derm Venereol 1983;63:349-52.
12. Lovell CR, Jayson MI. Joint involvement in systemic sclerosis. Scand J Rheumatol 1979;8:154-60.
13. Cuomo G, Zappia M, Abignano G, Iudici M, Rotondo A, Valentini G. Ultrasonographic features of the hand and wrist in systemic sclerosis. Rheumatology 2009;48:1414-7.
14. Low AH, Lax M, Johnson SR, Lee P. Magnetic resonance imaging of the hand in systemic sclerosis. J Rheumatol 2009;36:961-4.
15. Allanore Y, Seror R, Chevrot A, Kahan A, Drape JL. Hand vascular involvement assessed by magnetic resonance angiography in systemic sclerosis. Arthritis Rheum 2007;56:2747-54.
16. Schumacher HR Jr. Joint and periarticular involvement in systemic sclerosis. Clin Dermatol 1994;12:277-82.
17. Tuffanelli DL, Winkelmann RK. Systemic scleroderma. A clinical study of 727 cases. Arch Dermatol 1961;84:359-71.
18. Walker UA, Tyndall A, Czirjak L, Denton C, Farge-Bancel D, Kowal-Bielecka O, et al. Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Ann Rheum Dis 2007;66:754-63.
19. Allanore Y, Meune C, Vonk MC, Airò P, Hachulla E, Caramaschi P, et al. Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis. Ann Rheum Dis 2010;69:218-21.
20. Tyndall A, Mueller-Ladner U, Matucci-Cerinic M. Systemic sclerosis in Europe: first report from the EULAR Scleroderma Trials And Research (EUSTAR) group database. Ann Rheum Dis 2005;64:1107.
21. LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr, et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5. (Pubitemid 18073738)
22. Blocka KL, Bassett LW, Furst DE, Clements PJ, Paulus HE. The arthropathy of advanced progressive systemic sclerosis. A radiographic survey. Arthritis Rheum 1981;24:874-84.
23. Walker UA, Tyndall A, Czirjak L, Denton CP, Farge-Bancel D, Kowal-Bielecka O, et al. Geographical variation of disease manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials and Research (EUSTAR) group database. Ann Rheum Dis 2009;68:856-62.
24. Resnick D. Scleroderma (progressive systemic sclerosis). In: Diagnosis of bone and joint disorders. 2nd ed. Philadelphia: W.B. Saunders Company; 1988:1191-216.
25. Cohen MJ, Persellin RH. Coexistence of rheumatoid arthritis and systemic sclerosis in four patients. Scand J Rheumatol 1982;11:241-5.
26. Armstrong RD, Gibson T. Scleroderma and erosive polyarthritis: a disease entity? Ann Rheum Dis 1982;41:141-6.
27. Baron M, Srolovitz H, Lander P, Kapusta M. The coexistence of rheumatoid arthritis and scleroderma: a case report and review of the literature. J Rheumatol 1982;9:947-50. (Pubitemid 13119708)
28. Avouac J, Airò P, Dieude P, Caramaschi P, Tiev K, Diot E, et al. Associated autoimmune diseases in systemic sclerosis define a subset of patients with milder disease: results from 2 large cohorts of European Caucasian patients. J Rheumatol 2010;37:608-14.
29. Jinnin M, Ihn H, Yamane K, Asano Y, Yazawa N, Tamaki K. Clinical features of patients with systemic sclerosis accompanied by rheumatoid arthritis. Clin Exp Rheumatol 2003;21:91-4. (Pubitemid 36267538)
30. Szucs G, Szekanecz Z, Zilahi E, Kapitany A, Barath S, Szamosi S, et al. Systemic sclerosis-rheumatoid arthritis overlap syndrome: a unique combination of features suggests a distinct genetic, serological and clinical entity. Rheumatology 2007;46:989-93.
31. Avouac J, Gossec L, Dougados M. Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systematic literature review. Ann Rheum Dis 2006;65:845-51.
32. Morita Y, Muro Y, Sugiura K, Tomita Y. Anti-cyclic citrullinated peptide antibody in systemic sclerosis. Clin Exp Rheumatol 2008;26:542-7.
33. Marrone M, Chiala A, Tampoia M, Iannone F, Raho L, Covelli M, et al. [Prevalence of anti-CCP antibodies in systemic sclerosis]. Reumatismo 2007;59:20-4.
34. Schumacher HR Jr. Joint involvement in progressive systemic sclerosis (scleroderma): a light and electron microscopic study of synovial membrane and fluid. Am J Clin Pathol 1973;60:593-600.
35. Steen VD, Medsger TA Jr. The palpable tendon friction rub: an important physical examination finding in patients with systemic sclerosis. Arthritis Rheum 1997;40:1146-51.
36. Radic M, Martinovic Kaliterna D, Ljutic D. The level of anti-topoisomerase I antibodies highly correlates with metacarpophalangeal and proximal interphalangeal joints flexion contractures in patients with systemic sclerosis. Clin Exp Rheumatol 2006;24:407-12. (Pubitemid 44363542)
37. Valentini G, Silman AJ, Veale D. Assessment of disease activity. Clin Exp Rheumatol 2003;21:S39-41.