Faecal glucocorticoid metabolites: How to express yourself - Comparison of absolute amounts versus concentrations in samples from a study in laboratory rats

Laboratory Animals

Volumn 44, Issue 3, 2010, Pages 192-198

  Lepschy, M ^a   Touma, C ^b   Palme, R ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

Corticosterone; Expression of results; Laboratory animals; Rodents

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID; HYDROCORTISONE; DEXAMETHASONE;

ACCURACY; ADRENAL CORTEX; ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; COMPARATIVE STUDY; CONTROLLED STUDY; EXPERIMENTAL RAT; FECES; FEMALE; MALE; METABOLITE; NON INVASIVE MEASUREMENT; NONHUMAN; PHARMACOLOGICAL STIMULATION; PROVOCATION TEST; RAT; RELIABILITY; STRESS; VALIDATION PROCESS; VALIDATION STUDY; ANIMAL; CHEMICAL ANALYSIS; CHEMISTRY; DRUG EFFECTS; ENDOCRINE FUNCTION TEST; METABOLISM; PHYSIOLOGICAL STRESS; REPRODUCIBILITY; STANDARDS; STATISTICS AND NUMERICAL DATA;

ANIMALIA; RATTUS; RATTUS NORVEGICUS; RODENTIA;

ADRENAL CORTEX; ADRENAL CORTEX FUNCTION TESTS; ANIMALS; CHEMISTRY TECHNIQUES, ANALYTICAL; DEXAMETHASONE; FECES; FEMALE; GLUCOCORTICOIDS; MALE; RATS; REPRODUCIBILITY OF RESULTS; STRESS, PHYSIOLOGICAL;

EID: 77954429466     PISSN: 00236772     EISSN: None     Source Type: Journal    
DOI: 10.1258/la.2009.009082     Document Type: Article

References (26)

1. Möstl E, Palme R. Hormones as indicators of stress. Domest Anim Endocrinol 2002;23:67-74
2. Palme R, Rettenbacher S, Touma C, El-Bahr SM, Möstl E. Stress hormones in mammals and birds: comparative aspects regarding metabolism, excretion, and noninvasive measurement in fecal samples. Ann N Y Acad Sci 2005;1040:162-71
3. Palme R, Robia C, Messmann S, Hofer J, Möstl E. Measurement of faecal cortisol metabolites in ruminants: a non-invasive parameter of adrenocortical function. Wiener Tierärztliche Monatsschr 1999;86:237-41
4. Touma C, Palme R. Measuring fecal glucocorticoid metabolites in mammals and birds: the importance of validation. Ann N Y Acad Sci 2005;1046:54-74 (Pubitemid 41123863)
5. Blottner D, Serradj N, Salanova M, et al. Morphological, physiological and behavioural evaluation of a 'Mice In Space' housing system. J Comp Physiol B 2009;179:519-33
6. Dallmann R, Touma C, Palme R, Albrecht U, Steinlechner S. Impaired daily glucocorticoid rhythm in Per1Brd mice. J Comp Physiol A 2006;192:769-75
7. Touma C, Ambrée O, Görtz N, et al. Age- and sex-dependent development of adrenocortical hyperactivity in a transgenic mouse model of Alzheimer's disease (TgCRND8). Neurobiol Aging 2004;25:893-904
8. Voigtländer T, Unterberger U, Touma C, et al. Prominent corticosteroid disturbance in experimental prion disease. Eur J Neurosci 2006;23:2723-30
9. Touma C, Bunck M, Glasl L, et al. Mice selected for high versus low stress reactivity: a new animal model for affective disorders. Psychoneuroendocrinology 2008;33:839-10
10. Palme R. Measuring fecal steroids: guidelines for practical application. Ann N Y Acad Sci 2005;1046:75-80
11. Möstl E, Rettenbacher S, Palme R. Measurement of corticosterone metabolites in birds' droppings: an analytical approach. Ann N Y Acad Sci 2005;1046:17-34
12. Touma C, Palme R, Sachser N. Analyzing corticosterone metabolites in fecal samples of mice: a noninvasive technique to monitor stress hormones. Horm Behav 2004;45:10-22
13. Carlsson HE, Lyberg K, Royo F, Hau J. Quantification of stress sensitive markers in single fecal samples do not accurately predict excretion of these in pig. Res Vet Sci 2007;82:423-8 (Pubitemid 46554819)
14. Cavigelli SA, Monfort SL, Whitney TK, Mechref YS, Novotny M, McClintock MK. Frequent serial fecal corticoid measures from rats reflect circadian and ovarian corticosterone rhythms. J Endocrinol 2005;184:153-63
15. Royo F, Björk N, Carlsson HE, Mayo S, Hau J. Impact of chronic catheterization and automated blood sampling (Accusampler) on serum corticosterone and fecal immunoreactive corticosterone metabolites and immunoglobulin A in male rats. J Endocrinol 2004;180:145-53
16. Lepschy M, Touma C, Hruby R, Palme R. Non-invasive measurement of adrenocortical activity in male and female rats. Lab Anim 2007;41:372-87 (Pubitemid 47195609)
17. Lepschy M, Rettenbacher S, Touma C, Palme RG. Excretion of catecholamines in rats, mice and chickens. J Comp Physiol B 2008;178:629-36
18. Touma C, Sachser N, Möstl E, Palme R. Effect of sex and time of day on metabolism and excretion of corticosterone in urine and feces of mice. Gen Comp Endocrinol 2003;130:267-78
19. Siegel S, Castellan NJ. Nonparametric Statistics for the Behavioral Sciences. 2nd edn. New York: McGraw-Hill Book Company, 1988
20. Pihl L, Hau J. Faecal corticosterone and immunoglobulin A in young adult rats. Lab Anim 2003;37:166-71
21. Eriksson E, Royo F, Lyberg K, Carlsson HE, Hau J. Effect of metabolic cage housing on immunoglobulin A and corticosterone excretion in faeces and urine of young male rats. Exp Physiol 2004;89:427-33
22. Paramastri Y, Royo F, Eberova J, et al. Urinary and fecal immunoglobulin A, cortisol and 11-17 dioxoandrostanes, and serum cortisol in metabolic cage housed female cynomolgus monkeys (Macaca fascicularis). J Med Primatol 2007;36:355-64
23. Rabiee AR, Dalley D, Borman JM, Macmillan KL, Schwarzenberger F. Progesterone clearance rate in lactating dairy cows with two levels of dry matter and metabolisable energy intakes. Anim Reprod Sci 2002;72:11-25
24. Ambree O, Touma C, Görtz N, et al. Activity changes and marked stereotypic behavior precede Aß pathology in TgCRND8 Alzheimer mice. Neurobiol Aging 2005;27:955-64
25. Touma C, Fenzl T, Ruschel J, et al. Rhythmicity in mice selected for extremes in stress reactivity: behavioural, endocrine and sleep changes resembling endophenotypes of major depression. PLoS ONE 2009;4:e4325
26. Bamberg E, Palme R, Meingassner JG. Excretion of corticosteroid metabolites in urine and faeces of rats. Lab Anim 2001;35:307-14 (Pubitemid 32929793)