Intra-articular hyaluronic acid increases cartilage breakdown biomarker in patients with knee osteoarthritis

Clinical Rheumatology

Volumn 29, Issue 6, 2010, Pages 619-624

  Gonzalez Fuentes, Alexandra M ^b   Green, David M ^a,b   Rossen, Roger D ^a,b   Bernard, Ng ^a,b  

^a MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Collagen type II C telopeptide; Hyaluronic acid; Knee; Osteoarthritis

Indexed keywords

ANALGESIC AGENT; CARBOXY TERMINAL TELOPEPTIDE; CARBOXY TERMINAL TYPE 2 COLLAGEN TELOPEPTIDE; COLLAGEN; HYALURONIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; STEROID; TRAMADOL; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; INJECTION; KINETICS; KNEE OSTEOARTHRITIS; KNEE PAIN; MALE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROTEIN URINE LEVEL; TREATMENT RESPONSE; URINALYSIS;

AGED; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; CARTILAGE, ARTICULAR; COLLAGEN TYPE II; FEMALE; HUMANS; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PATIENT SELECTION; PILOT PROJECTS;

EID: 77954426432     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10067-010-1376-8     Document Type: Article

References (34)

1. Felson DT, Naimark A, Anderson J, Kazis L, Castelli W, Meenan RF (1987) The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum 30(8):914-918
2. National Center for Chronic Disease Prevention and Health Promotion (2008) http://www.cdc.gov/arthritis/arthritis/osteoarthritis.htm. Last revised: January 11
3. Supartz package insert. In: Smith and Nephew, Memphis; Revised: January 30 2007
4. Brzusek D, Petron D (2008) Treating knee osteoarthritis with intra-articular hyaluronans. Curr Med Res Opin 24(12):3307-3322
5. Caborn D, Rush J, Lanzer W, Parenti D, Murray C (2004) A randomized, single-blind comparison of the efficacy and tolerability of hylan G-F 20 and triamcinolone hexacetonide in patients with osteoarthritis of the knee. J Rheumatol 31(2):333-343
6. Lisignoli G, Grassi F, Zini N, Toneguzzi S, Piacentini A, Guidolin D et al (2001) Anti-Fas-induced apoptosis in chondrocytes reduced by hyaluronan: evidence for CD44 and CD54 (intercellular adhesion molecule 1) invovement. Arthritis Rheum 44(8):1800-1807
7. Christgau S, Garnero P, Fledelius C, Moniz C, Ensig M, Gineyts E et al (2001) Collagen type II C-telopeptide fragments as an index of cartilage degradation. Bone 29(3):209-215
8. Garnero P, Ayral X, Rousseau JC, Christgau S, Sandell LJ, Dougados M et al (2002) Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis. Arthritis Rheum 46(10):2613-2624
9. Garnero P, Conrozier T, Christgau S, Mathieu P, Delmas PD, Vignon E (2003) Urinary type II collagen C-telopeptide levels are increased in patients with rapidly destructive hip osteoarthritis. Ann Rheum Dis 62(10):939-943
10. Reijman M, Hazes JM, Bierma-Zeinstra SM, Koes BW, Christgau S, Christiansen C et al (2004) A new marker for osteoarthritis: cross-sectional and longitudinal approach. Arthritis Rheum 50(8):2471-2478
11. Jordan KM, Syddall HE, Garnero P, Gineyts E, Dennison EM, Sayer AA et al (2006) Urinary CTX-II and glucosyl-galactosyl-pyridinoline are associated with the presence and severity of radiographic knee osteoarthritis in men. Ann Rheum Dis 65(7):871-877
12. Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P (2006) Hellio Le Graverand MP, et al. Urinary CTX-II levels are associated with radiographic subtypes of osteoarthritis in hip, knee, hand, and facet joints in subject with familial osteoarthritis at multiple sites: the GARP study. Ann Rheum Dis 65(3):360-365
13. Bruyere O, Collette J, Kothari M, Zaim S, White D, Genant H et al (2006) Osteoarthritis, magnetic resonance imaging, and biochemical markers: a one year prospective study. Ann Rheum Dis 65(8):1050-1054
14. Garnero P, Peterfy C, Zaim S, Schoenharting M (2005) Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis: a three-month longitudinal study. Arthritis Rheum 52(9):2822-2829
15. Bedson J, Croft PR (2008) The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature. BMC Musculoskelet Disord 9:116
16. Zhai G, Cicuttini F, Ding C, Scott F, Garnero P, Jones G (2007) Correlates of knee pain in younger subjects. Clin Rheumatol 26(1):75-80
17. Gineyts E, Mo JA, Ko A, Henriksen DB, Curtis SP, Gertz BJ et al (2004) Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis. Ann Rheum Dis 63(7):857-861
18. Kong SY, Stabler TV, Criscione LG, Elliott AL, Jordan JM, Kraus VB (2006) Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis. Arthritis Rheum 54(8):2496-2504
19. Qvist P, Munk M, Hoyle N, Christiansen C (2004) Serum and plasma fragments of C-telopeptides of type I collagen (CTX) are stable during storage at low temperatures for 3 years. Clin Chim Acta 350(1-2):167-173
20. Pozo MA, Balazs EA, Belmonte C (1997) Reduction of sensory responses to passive movements of inflamed knee joints by hylan, a hyaluronan derivative. Exp Brain Res 116(1):3-9
21. Gomis A, Miralles A, Schmidt RF, Belmonte C (2007) Nociceptive nerve activity in an experimental model of knee joint osteoarthritis of the guinea pig: effect of intra-articular hyaluronan application. Pain 130(1-2):126-136
22. Gomis A, Miralles A, Schmidt RF, Belmonte C (2009) Intra-articular injections of hyaluronan solutions of different elastoviscosity reduce nociceptive nerve activity in a model of osteoarthritic knee joint of the guinea pig. Osteoarthritis Cartilage 17(6):798-804
23. Knudson W, Casey B, Nishida Y, Eger W, Kuettner KE, Knudson CB (2000) Hyaluronan oligosaccharides perturb cartilage matrix homeostasis and induce chondrocytic chondrolysis. Arthritis Rheum 43(5):1165-1174
24. Termeer CC, Hennies J, Voith U, Ahrens T, Weiss JM, Prehm P et al (2000) Oligosaccharides of hyaluronan are potent activators of dendritic cells. J Immunol 165(4):1863-1870
25. Fernandes JC, Martel-Pelletier J, Pelletier JP (2002) The role of cytokines in osteoarthritis pathophysiology. Biorheology 39(1-2):237-246
26. Lohmander LS, Atley LM, Pietka TA, Eyre DR (2003) The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis. Arthritis Rheum 48(11):3130-3139
27. Nielsen RH, Stoop R, Leeming DJ, Stolina M, Qvist P, Christiansen C et al (2008) Evaluation of cartilage damage by measuring collagen degradation products in joint extracts in a traumatic model of osteoarthritis. Biomarkers 13(1):79-87
28. Kim HJ, Lee YH, Kim CK (2009) Changes in serum cartilage oligomeric matrix protein (COMP), plasma CPK and plasma hs-CRP in relation to running distance in a marathon (42.195 km) and an ultra-marathon (200 km) race. Eur J Appl Physiol 105(5):765-770
29. Garnero P, Piperno M, Gineyts E, Christgau S, Delmas PD, Vignon E (2001) Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage. Ann Rheum Dis 60(6):619-626
30. Depuy Website: http://www.orthoviscline.com/replace-whatmissing/safety
31. Bagger YZ, Tanko LB, Alexandersen P, Karsdal MA, Olson M, Mindeholm L et al (2005) Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis. Bone 37(3):425-430
32. Manicourt DH, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP (2006) Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum 54(10):3205-3211
33. Manicourt DH, Bevilacqua M, Righini V, Famaey JP, Devogelaer JP (2005) Comparative effect of nimesulide and ibuprofen on the urinary levels of collagen type II C-telopeptide degradation products and on the serum levels of hyaluronan and matrix metalloproteinases-3 and -13 in patients with flare-up of osteoarthritis. Drugs R D 6(5):261-271
34. Lehmann HJ, Mouritzen U, Christgau S, Cloos PA, Christiansen C (2002) Effect of bisphosphonates on cartilage turnover assessed with a newly developed assay for collagen type II degradation products. Ann Rheum Dis 61(6):530-533